Detail Information

Basic Information:


  VIRBase ID:  

HHID00076002

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-101-2-5p:           FZD6:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-101-2-5p FZD6
miRBase
Accession/Entrez ID		 MIMAT0037312 8323
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - FZ-6//FZ6//HFZ6//NDNC1//NDNC10

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-101-2-5p
rs1189997653 chr9:4850323    C/G
rs1411860402 chr9:4850328    G/C
rs1472339708 chr9:4850325    G/A
rs374692878 chr9:4850308    T/C
rs752365347 chr9:4850320    G/C
rs758036961 chr9:4850324    C/T
rs777507775 chr9:4850326    A/G
rs570832031 chr9:4850310    G/A
rs570832031 chr9:4850310    G/T
rs766953168 chr9:4850309    C/T
rs779213487 chr9:4850315    T/C
rs894878476 chr9:4850314    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR FZD6
chr8:104322548(+) A-I      intronic
chr8:104343872(+) A-I      3'UTR
chr8:104343870(+) A-I      3'UTR
chr8:104343871(+) A-I      3'UTR
chr8:104343876(+) A-I      3'UTR
chr8:104322783(+) A-I      intronic
chr8:104322740(+) A-I      intronic
chr8:104323737(+) A-I      intronic
chr8:104323784(+) A-I      intronic
chr8:104323780(+) A-I      intronic
chr8:104322578(+) A-I      intronic
chr8:104323711(+) A-I      intronic
chr8:104323791(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED FZD6
chr8:104323711(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase FZD6
chr8:104311197-104311198(+) m6A 5'UTR//intron       24981863
chr8:104312196-104312197(+) m6A 5'UTR       24981863
chr8:104312250-104312251(+) m6A 5'UTR       24981863
chr8:104330862-104330863(+) m6A 3'UTR//CDS//intron       24284625
chr8:104330900-104330901(+) m6A 3'UTR//CDS//intron       24284625
chr8:104330930-104330931(+) m6A 3'UTR//CDS//intron       24284625
chr8:104336727-104336728(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//22608085
chr8:104336781-104336782(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//26404942//22608085
chr8:104336786-104336787(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//26404942//22608085
chr8:104336800-104336801(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//26404942//22608085
chr8:104336832-104336833(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//26404942//22608085
chr8:104336843-104336844(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//26404942//22608085
chr8:104336943-104336944(+) m6A 3'UTR//CDS//intron       24284625//24209618//24981863//22608085
chr8:104337029-104337030(+) m6A 3'UTR//CDS//intron       24284625//24209618//24981863//22608085
chr8:104337333-104337334(+) m6A 3'UTR//CDS       24284625//24981863//22575960//22608085
chr8:104337370-104337371(+) m6A 3'UTR//CDS       24284625//24981863//22575960//22608085
chr8:104337385-104337386(+) m6A 3'UTR//CDS       24284625//24981863//22575960//22608085
chr8:104341954-104341955(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22608085
chr8:104341975-104341976(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22608085
chr8:104342018-104342019(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22608085
chr8:104342086-104342087(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr8:104342093-104342094(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr8:104342111-104342112(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr8:104342123-104342124(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr8:104342176-104342177(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr8:104342181-104342182(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr8:104342191-104342192(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr8:104342221-104342222(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr8:104342233-104342234(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr8:104343643-104343644(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22608085
chr8:104343740-104343741(+) m6A 3'UTR       24284625//24209618//24981863//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate FZD6
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HeLa-S3 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-101-2-5p
Interactor2: FZD6

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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