Detail Information

Basic Information:


  VIRBase ID:  

HHID00075911

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-196a-1-3p:           MED10:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-196a-1-3p MED10
miRBase
Accession/Entrez ID		 MIMAT0037307 84246
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - L6//NUT2//TRG20

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-196a-1-3p
rs1312793718 chr17:48632506    A/G
rs1408763134 chr17:48632499    G/A
rs186449583 chr17:48632497    G/A
rs751860800 chr17:48632495    TC/T
rs373603936 chr17:48632514    T/C
rs374872332 chr17:48632510    T/C
rs556956624 chr17:48632513    T/C
rs759524926 chr17:48632507    ATGT/A

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MED10
chr5:6372463-6372464(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960//22608085
chr5:6372507-6372508(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr5:6372519-6372520(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr5:6372556-6372557(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr5:6372580-6372581(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr5:6372664-6372665(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr5:6372687-6372688(-) m6A CDS//exon       24284625//24209618//27773535//22608085
chr5:6378543-6378544(-) m6A CDS//exon       24284625//24981863//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate MED10
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-196a-1-3p
Interactor2: MED10

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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