Detail Information

Basic Information:


  VIRBase ID:  

HHID00075881

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-196a-1-3p:           OTUD6B:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-196a-1-3p OTUD6B
miRBase
Accession/Entrez ID
MIMAT0037307 51633
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CGI-77//DUBA-5//DUBA5//IDDFSDA

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-196a-1-3p
rs1312793718 chr17:48632506    A/G
rs1408763134 chr17:48632499    G/A
rs186449583 chr17:48632497    G/A
rs751860800 chr17:48632495    TC/T
rs373603936 chr17:48632514    T/C
rs374872332 chr17:48632510    T/C
rs556956624 chr17:48632513    T/C
rs759524926 chr17:48632507    ATGT/A

RNA Editing:


Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED OTUD6B
chr8:92083424(+) A-I exon CDS    19478186
chr8:92083861(+) C-T intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase OTUD6B
chr8:92082681-92082682(+) m1A 5'UTR//CDS//exon       26863196//26863410
chr8:92083462-92083463(+) m6A 5'UTR//CDS//exon       24981863//27773535
chr8:92083468-92083469(+) m6A 5'UTR//CDS//exon       24981863//27773535
chr8:92083480-92083481(+) m6A 5'UTR//CDS//exon       24981863//27773535
chr8:92086086-92086087(+) m6A 5'UTR//CDS//exon       24981863
chr8:92090644-92090645(+) m6A 3'UTR//CDS//exon       24981863//22608085
chr8:92090660-92090661(+) m6A 3'UTR//CDS//exon       24981863//22608085
chr8:92090678-92090679(+) m6A 3'UTR//CDS//exon       24981863//22608085
chr8:92090702-92090703(+) m6A 3'UTR//CDS//exon       24981863//22608085
chr8:92090717-92090718(+) m6A 3'UTR//CDS//exon       24981863//22608085
chr8:92090814-92090815(+) m6A 3'UTR//CDS//exon       22608085
chr8:92090845-92090846(+) m6A 3'UTR//CDS//exon       22608085
chr8:92090866-92090867(+) m6A 3'UTR//CDS//exon       22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate OTUD6B
Exosome Urine     25135963
Exosome Blood     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-196a-1-3p
Interactor2: OTUD6B

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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