Basic Information:

  VIRBase ID:  

HHID00075755

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-103a-1-5p:  MIMAT0037306          CYB5D1:  NM_144607     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-103a-1-5p	CYB5D1
miRBase Accession/Entrez ID	MIMAT0037306	124637
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-103a-1-5p	rs1031876357 chr5:168560948    G/A rs1257538371 chr5:168560953    G/A rs201456319 chr5:168560963    C/T rs763264678 chr5:168560952    T/C rs771317046 chr5:168560954    T/C rs773654610 chr5:168560950    A/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CYB5D1	chr17:7778330(+) A-I      intronic chr17:7778325(+) A-I      intronic chr17:7778319(+) A-I      intronic chr17:7765936(+) A-I      intronic chr17:7775953(+) A-I      intronic chr17:7778501(+) A-I      intronic chr17:7778419(+) A-I      intronic chr17:7775941(+) A-I      intronic chr17:7775940(+) A-I      intronic chr17:7778465(+) A-I      intronic chr17:7778495(+) A-I      intronic chr17:7778497(+) A-I      intronic chr17:7778454(+) A-I      intronic chr17:7778288(+) A-I      intronic chr17:7778273(+) A-I      intronic chr17:7778258(+) A-I      intronic chr17:7765896(+) A-I      intronic chr17:7775903(+) A-I      intronic chr17:7778304(+) A-I      intronic chr17:7765897(+) A-I      intronic chr17:7765937(+) A-I      intronic chr17:7766022(+) A-I      intronic chr17:7765934(+) A-I      intronic chr17:7765946(+) A-I      intronic chr17:7765880(+) A-I      intronic chr17:7765877(+) A-I      intronic chr17:7765869(+) A-I      intronic chr17:7778305(+) A-I      intronic chr17:7778500(+) A-I      intronic chr17:7778332(+) A-I      intronic chr17:7768163(+) A-I      intronic chr17:7767798(+) A-I      intronic chr17:7767953(+) A-I      intronic chr17:7767902(+) A-I      intronic chr17:7770924(+) A-I      intronic chr17:7765906(+) A-I      intronic chr17:7778873(+) A-I      intronic chr17:7778427(+) A-I      intronic chr17:7769697(+) A-I      intronic chr17:7778271(+) A-I      intronic chr17:7765891(+) A-I      intronic chr17:7767835(+) A-I      intronic chr17:7769633(+) A-I      intronic chr17:7778792(+) A-I      intronic chr17:7778786(+) A-I      intronic chr17:7768064(+) A-I      intronic chr17:7765806(+) A-I      intronic chr17:7778718(+) A-I      intronic chr17:7778426(+) A-I      intronic chr17:7778083(+) A-I      intronic chr17:7778093(+) A-I      intronic chr17:7767781(+) A-I      intronic chr17:7778844(+) A-I      intronic chr17:7768015(+) A-I      intronic chr17:7767889(+) A-I      intronic chr17:7778274(+) A-I      intronic chr17:7778468(+) A-I      intronic chr17:7767825(+) A-I      intronic chr17:7770840(+) A-I      intronic chr17:7765870(+) A-I      intronic chr17:7778915(+) A-I      intronic chr17:7777949(+) A-I      intronic chr17:7770737(+) A-I      intronic chr17:7767788(+) A-I      intronic chr17:7778441(+) A-I      intronic chr17:7767892(+) A-I      intronic chr17:7778362(+) A-I      intronic chr17:7778084(+) A-I      intronic chr17:7763599(+) A-I      3'UTR chr17:7778361(+) A-I      intronic chr17:7778393(+) A-I      intronic chr17:7778496(+) A-I      intronic chr17:7778149(+) A-I      intronic chr17:7778838(+) A-I      intronic chr17:7765792(+) A-I      intronic chr17:7767738(+) A-I      intronic chr17:7765905(+) A-I      intronic chr17:7765977(+) A-I      intronic chr17:7768105(+) A-I      intronic chr17:7778089(+) A-I      intronic chr17:7778685(+) A-I      intronic chr17:7765800(+) A-I      intronic chr17:7777971(+) A-I      intronic chr17:7778717(+) A-I      intronic chr17:7767780(+) A-I      intronic chr17:7778438(+) A-I      intronic chr17:7768040(+) A-I      intronic chr17:7765778(+) A-I      intronic chr17:7778313(+) A-I      intronic chr17:7778415(+) A-I      intronic chr17:7770677(+) A-I      intronic chr17:7778723(+) A-I      intronic chr17:7767708(+) A-I      intronic chr17:7778782(+) A-I      intronic chr17:7778312(+) A-I      intronic chr17:7778929(+) A-I      intronic chr17:7770713(+) A-I      intronic chr17:7770837(+) A-I      intronic chr17:7778853(+) A-I      intronic chr17:7778888(+) A-I      intronic chr17:7778825(+) A-I      intronic chr17:7778409(+) A-I      intronic chr17:7763649(+) A-I      3'UTR

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CYB5D1	chr17:7761236-7761237(+) m6A 5'UTR       24981863 chr17:7761258-7761259(+) m6A 5'UTR       24981863//22608085 chr17:7761273-7761274(+) m6A 5'UTR       24981863//22608085 chr17:7761318-7761319(+) m6A 5'UTR       24284625//24981863//22608085 chr17:7761788-7761789(+) m6A 3'UTR//CDS//exon//intron       24284625 chr17:7761812-7761813(+) m6A exon//intron       24284625 chr17:7761909-7761910(+) m6A exon//intron       24284625//25456834//22608085 chr17:7762017-7762018(+) m6A 3'UTR//CDS//exon//intron       24284625//25456834//24981863//22608085 chr17:7762088-7762089(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr17:7762423-7762424(+) m6A intron       - chr17:7762434-7762435(+) m6A intron       - chr17:7762477-7762478(+) m6A intron       - chr17:7762536-7762537(+) m6A intron       - chr17:7762793-7762794(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr17:7762799-7762800(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr17:7762954-7762955(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr17:7763025-7763026(+) m6A 3'UTR       24209618//25456834//24981863//22575960//22608085 chr17:7763209-7763210(+) m6A 3'UTR       24981863//27773535//22608085 chr17:7763260-7763261(+) m6A 3'UTR       24981863//27773535//22575960//22608085 chr17:7763388-7763389(+) m6A 3'UTR       27773535//22608085 chr17:7764206-7764207(+) m6A 3'UTR       24981863 chr17:7764294-7764295(+) m6A 3'UTR       24981863 chr17:7764348-7764349(+) m6A 3'UTR       24981863 chr17:7764373-7764374(+) m6A 3'UTR       24981863 chr17:7764396-7764397(+) m6A 3'UTR       24981863 chr17:7764624-7764625(+) m6A 3'UTR       24981863 chr17:7764636-7764637(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CYB5D1	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-103a-1-5p
Interactor2: CYB5D1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.