Detail Information

Basic Information:


  VIRBase ID:  

HHID00075638

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-103a-1-5p:           NFKBIA:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-103a-1-5p NFKBIA
miRBase
Accession/Entrez ID		 MIMAT0037306 4792
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - EDAID2//IKBA//MAD-3//NFKBI

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-103a-1-5p
rs1031876357 chr5:168560948    G/A
rs1257538371 chr5:168560953    G/A
rs201456319 chr5:168560963    C/T
rs763264678 chr5:168560952    T/C
rs771317046 chr5:168560954    T/C
rs773654610 chr5:168560950    A/C

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase NFKBIA
chr14:35870732-35870733(-) m6A 3'UTR       27773535
chr14:35870932-35870933(-) m6A 3'UTR       24981863//26404942//27773535
chr14:35870984-35870985(-) m6A 3'UTR       24284625//25456834//24981863//26404942//27773535
chr14:35870995-35870996(-) m6A 3'UTR       24284625//25456834//24981863//26404942//27773535//22608085
chr14:35871038-35871039(-) m6A 3'UTR       24284625//25456834//24981863//26404942//27773535//22608085
chr14:35871128-35871129(-) Y 3'UTR       26075521
chr14:35871192-35871193(-) m6A 3'UTR//exon       24284625//24981863//28052920//26404942//27773535//27371828//22608085
chr14:35871198-35871199(-) m6A 3'UTR//exon       24284625//24981863//28052920//26404942//27773535//27371828//22608085
chr14:35871678-35871679(-) m6A 3'UTR//CDS//exon       24284625//26404942//27773535//22575960
chr14:35871828-35871829(-) m6A 3'UTR//CDS//exon//intron       27773535
chr14:35871850-35871851(-) m6A 3'UTR//CDS//exon//intron       27773535
chr14:35872480-35872481(-) m6A 3'UTR//CDS//exon       24284625//27773535//22575960
chr14:35872565-35872566(-) m6A CDS//exon       27773535//22575960
chr14:35872623-35872624(-) m6A exon//intron       27773535
chr14:35872908-35872909(-) m6A CDS//exon//intron       27773535
chr14:35872932-35872933(-) m6A CDS//exon//intron       27773535
chr14:35873151-35873152(-) m6A 5'UTR//intron       -
chr14:35873626-35873627(-) m6A CDS//exon       27371828
chr14:35873746-35873747(-) m6A CDS//exon       24284625//26404942//27371828//27773536
chr14:35873786-35873787(-) m1A CDS//exon       26863196//26863410

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate NFKBIA
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-103a-1-5p
Interactor2: NFKBIA

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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