Detail Information

Basic Information:


  VIRBase ID:  

HHID00075540

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-128-2-5p:           USP46:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-128-2-5p USP46
miRBase
Accession/Entrez ID		 MIMAT0031095 64854
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-128-2-5p
rs1300414924 chr3:35744490    G/A
rs1305340991 chr3:35744500    A/G
rs773585541 chr3:35744508    C/T
rs1273290796 chr3:35744497    G/A
rs748691104 chr3:35744494    G/A
rs769991861 chr3:35744496    C/T
rs920224719 chr3:35744492    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR USP46
chr4:53472550(-) A-I      intronic
chr4:53506806(-) A-I      intronic
chr4:53506854(-) A-I      intronic
chr4:53502810(-) A-I      intronic
chr4:53502688(-) A-I      intronic
chr4:53500780(-) A-I      intronic
chr4:53500768(-) A-I      intronic
chr4:53500759(-) A-I      intronic
chr4:53482748(-) A-I      intronic
chr4:53482735(-) A-I      intronic
chr4:53472549(-) A-I      intronic
chr4:53472517(-) A-I      intronic
chr4:53472534(-) A-I      intronic
chr4:53472548(-) A-I      intronic
chr4:53503074(-) A-I      intronic
chr4:53503061(-) A-I      intronic
chr4:53502790(-) A-I      intronic
chr4:53500441(-) A-I      intronic
chr4:53502787(-) A-I      intronic
chr4:53503178(-) A-I      intronic
chr4:53500484(-) A-I      intronic
chr4:53502761(-) A-I      intronic
chr4:53505966(-) A-I      intronic
chr4:53520771(-) A-I      intronic
chr4:53506861(-) A-I      intronic
chr4:53503147(-) A-I      intronic
chr4:53506887(-) A-I      intronic
chr4:53500864(-) A-I      intronic
chr4:53503150(-) A-I      intronic
chr4:53503015(-) A-I      intronic
chr4:53503116(-) A-I      intronic
chr4:53505992(-) A-I      intronic
chr4:53503045(-) A-I      intronic
chr4:53500455(-) A-I      intronic
chr4:53503098(-) A-I      intronic
chr4:53502773(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED USP46
chr4:53500864(-) A-G intron -    22484847
chr4:53502761(-) A-G intron -    22484847
chr4:53502787(-) A-G intron -    22484847
chr4:53502790(-) A-G intron -    22484847
chr4:53506861(-) A-G intron -    22484847
chr4:53506887(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase USP46
chr4:53457140-53457141(-) m6A 3'UTR       27773535
chr4:53457197-53457198(-) m6A 3'UTR       27773535
chr4:53457329-53457330(-) m6A 3'UTR       24209618//27773535//22608085
chr4:53457368-53457369(-) m6A 3'UTR       24209618//27773535//22608085
chr4:53457383-53457384(-) m6A 3'UTR       24209618//27773535//22608085
chr4:53457508-53457509(-) m6A 3'UTR       27773535
chr4:53457514-53457515(-) m6A 3'UTR       27773535
chr4:53461038-53461039(-) m6A 3'UTR       24981863//22608085
chr4:53461486-53461487(-) m6A 3'UTR       24981863
chr4:53462268-53462269(-) m6A 3'UTR       24981863
chr4:53462298-53462299(-) m6A 3'UTR       24981863//22608085
chr4:53462371-53462372(-) m6A 3'UTR       24981863//22608085
chr4:53462389-53462390(-) m6A 3'UTR       24981863//22608085
chr4:53462397-53462398(-) m6A 3'UTR       24981863//22608085
chr4:53462431-53462432(-) m6A 3'UTR       24981863//22608085
chr4:53462438-53462439(-) m6A 3'UTR       24981863//22608085
chr4:53463669-53463670(-) m6A 3'UTR       24284625//25456834//24981863//27371828//22608085
chr4:53463788-53463789(-) m6A 3'UTR       24284625//25456834//24981863//27371828//22608085
chr4:53463797-53463798(-) m6A 3'UTR       24284625//25456834//24981863//27371828//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-128-2-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
USP46
Chromatin K562 cells     -
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-128-2-5p
Interactor2: USP46

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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