Detail Information

Basic Information:


  VIRBase ID:  

HHID00075489

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-128-2-5p:           TGOLN2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-128-2-5p TGOLN2
miRBase
Accession/Entrez ID		 MIMAT0031095 10618
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - hTGN46//hTGN48//hTGN51//TGN38//TGN46//TGN48//TGN51//TTGN2

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-128-2-5p
rs1300414924 chr3:35744490    G/A
rs1305340991 chr3:35744500    A/G
rs773585541 chr3:35744508    C/T
rs1273290796 chr3:35744497    G/A
rs748691104 chr3:35744494    G/A
rs769991861 chr3:35744496    C/T
rs920224719 chr3:35744492    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TGOLN2
chr2:85546354(-) A-I      3'UTR
chr2:85550545(-) A-I      intronic
chr2:85546422(-) A-I      3'UTR
chr2:85546480(-) A-I      3'UTR
chr2:85550353(-) A-I      intronic
chr2:85550247(-) A-I      intronic
chr2:85546472(-) A-I      3'UTR
chr2:85550645(-) A-I      intronic
chr2:85550532(-) A-I      intronic
chr2:85550509(-) A-I      intronic
chr2:85550472(-) A-I      intronic
chr2:85550261(-) A-I      intronic
chr2:85550206(-) A-I      intronic
chr2:85550197(-) A-I      intronic
chr2:85550190(-) A-I      intronic
chr2:85550130(-) A-I      intronic
chr2:85550169(-) A-I      intronic
chr2:85551419(-) A-I      intronic
chr2:85546504(-) A-I      3'UTR
chr2:85546514(-) A-I      3'UTR
chr2:85546416(-) A-I      3'UTR
chr2:85546527(-) A-I      3'UTR
chr2:85546468(-) A-I      3'UTR
chr2:85546525(-) A-I      3'UTR
chr2:85546483(-) A-I      3'UTR
chr2:85546384(-) A-I      3'UTR
chr2:85546366(-) A-I      3'UTR
chr2:85546495(-) A-I      3'UTR
chr2:85546358(-) A-I      3'UTR
chr2:85546496(-) A-I      3'UTR
chr2:85546353(-) A-I      3'UTR
chr2:85546566(-) A-I      3'UTR
chr2:85546471(-) A-I      3'UTR
chr2:85546533(-) A-I      3'UTR
chr2:85551427(-) A-I      intronic
chr2:85551289(-) A-I      intronic
chr2:85550534(-) A-I      intronic
chr2:85550446(-) A-I      intronic
chr2:85550626(-) A-I      intronic
chr2:85550362(-) A-I      intronic
chr2:85550432(-) A-I      intronic
chr2:85550526(-) A-I      intronic
chr2:85550264(-) A-I      intronic
chr2:85550620(-) A-I      intronic
chr2:85550186(-) A-I      intronic
chr2:85551443(-) A-I      intronic
chr2:85550315(-) A-I      intronic
chr2:85550269(-) A-I      intronic
chr2:85550318(-) A-I      intronic
chr2:85550168(-) A-I      intronic
chr2:85550497(-) A-I      intronic
chr2:85550687(-) A-I      intronic
chr2:85550270(-) A-I      intronic
chr2:85550541(-) A-I      intronic
chr2:85546426(-) A-I      3'UTR
chr2:85546429(-) A-I      3'UTR
chr2:85546368(-) A-I      3'UTR
chr2:85546479(-) A-I      3'UTR
chr2:85546406(-) A-I      3'UTR
chr2:85546373(-) A-I      3'UTR
chr2:85546477(-) A-I      3'UTR
chr2:85546536(-) A-I      3'UTR
chr2:85546433(-) A-I      3'UTR
chr2:85546478(-) A-I      3'UTR
chr2:85546572(-) A-I      3'UTR
chr2:85546571(-) A-I      3'UTR
chr2:85546494(-) A-I      3'UTR
chr2:85546457(-) A-I      3'UTR
chr2:85546412(-) A-I      3'UTR
chr2:85546465(-) A-I      3'UTR
chr2:85546517(-) A-I      3'UTR
chr2:85546390(-) A-I      3'UTR
chr2:85550643(-) A-I      intronic
chr2:85550470(-) A-I      intronic
chr2:85550232(-) A-I      intronic
chr2:85550606(-) A-I      intronic
chr2:85550273(-) A-I      intronic
chr2:85550603(-) A-I      intronic
chr2:85550540(-) A-I      intronic
chr2:85551395(-) A-I      intronic
chr2:85550216(-) A-I      intronic
chr2:85550286(-) A-I      intronic
chr2:85550285(-) A-I      intronic
chr2:85550267(-) A-I      intronic
chr2:85550370(-) A-I      intronic
chr2:85550577(-) A-I      intronic
chr2:85550651(-) A-I      intronic
chr2:85550268(-) A-I      intronic
chr2:85550372(-) A-I      intronic
chr2:85550221(-) A-I      intronic
chr2:85550309(-) A-I      intronic
chr2:85551382(-) A-I      intronic
chr2:85550163(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TGOLN2
chr2:85546373(-) A-I exon 3'UTR    22327324
chr2:85546465(-) A-I exon 3'UTR    22327324
chr2:85546474(-) A-I exon 3'UTR    22327324
chr2:85546517(-) A-I exon 3'UTR    22327324
chr2:85550186(-) A-I intron -    21960545   //22327324
chr2:85550221(-) A-I intron -    22327324
chr2:85550273(-) A-I intron -    22327324
chr2:85550589(-) A-I intron -    22327324
chr2:85550606(-) A-I intron -    22327324
chr2:85550168(-) A-I intron -    21960545
chr2:85546457(-) A-I exon 3'UTR    21960545
chr2:85546474(-) A-G exon 3'UTR    21725310   //22484847
chr2:85546301(-) G-A exon 3'UTR    22484847
chr2:85546373(-) A-G exon 3'UTR    22484847
chr2:85546397(-) A-G exon 3'UTR    22484847
chr2:85546398(-) A-G exon 3'UTR    22484847
chr2:85546439(-) A-G exon 3'UTR    22484847
chr2:85546451(-) A-G exon 3'UTR    22484847
chr2:85546457(-) A-G exon 3'UTR    22484847
chr2:85546465(-) A-G exon 3'UTR    22484847
chr2:85546470(-) A-G exon 3'UTR    22484847
chr2:85546476(-) A-G exon 3'UTR    22484847
chr2:85546477(-) A-G exon 3'UTR    22484847
chr2:85546478(-) A-G exon 3'UTR    22484847
chr2:85546517(-) A-G exon 3'UTR    22484847
chr2:85546519(-) A-G exon 3'UTR    22484847
chr2:85546536(-) A-G exon 3'UTR    22484847
chr2:85546571(-) A-G exon 3'UTR    22484847
chr2:85546572(-) A-G exon 3'UTR    22484847
chr2:85550134(-) A-G intron -    22484847
chr2:85550136(-) A-G intron -    22484847
chr2:85550158(-) A-G intron -    22484847
chr2:85550163(-) A-G intron -    22484847
chr2:85550186(-) A-G intron -    22484847
chr2:85550198(-) A-G intron -    22484847
chr2:85550216(-) A-G intron -    22484847
chr2:85550221(-) A-G intron -    22484847
chr2:85550225(-) A-G intron -    22484847
chr2:85550268(-) A-G intron -    22484847
chr2:85550269(-) A-G intron -    22484847
chr2:85550270(-) A-G intron -    22484847
chr2:85550273(-) A-G intron -    22484847
chr2:85550318(-) A-G intron -    22484847
chr2:85550323(-) A-G intron -    22484847
chr2:85550497(-) A-G intron -    22484847
chr2:85550526(-) A-G intron -    22484847
chr2:85550534(-) A-G intron -    22484847
chr2:85550540(-) A-G intron -    22484847
chr2:85550541(-) A-G intron -    22484847
chr2:85550549(-) G-A intron -    22484847
chr2:85550589(-) A-G intron -    22484847
chr2:85550603(-) A-G intron -    22484847
chr2:85550606(-) A-G intron -    22484847
chr2:85550607(-) A-G intron -    22484847
chr2:85550620(-) A-G intron -    22484847
chr2:85550642(-) A-G intron -    22484847
chr2:85550643(-) A-G intron -    22484847
chr2:85550651(-) A-G intron -    22484847
chr2:85550687(-) A-G intron -    22484847
chr2:85551427(-) A-G intron -    22484847
chr2:85551443(-) A-G intron -    22484847
chr2:85551460(-) A-G intron -    22484847
chr2:85551483(-) A-G intron -    22484847
chr2:85551496(-) A-G intron -    22484847
chr2:85551507(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TGOLN2
chr2:85545423-85545424(-) m6A 3'UTR       26404942
chr2:85545477-85545478(-) m6A 3'UTR       26404942
chr2:85545663-85545664(-) m6A 3'UTR       24284625//26404942
chr2:85545709-85545710(-) m6A 3'UTR       24284625//26404942
chr2:85545734-85545735(-) m6A 3'UTR       24284625//26404942
chr2:85545819-85545820(-) m6A 3'UTR       24284625//26404942
chr2:85545899-85545900(-) m6A 3'UTR       26404942
chr2:85546328-85546329(-) m6A 3'UTR       24981863//26404942
chr2:85546352-85546353(-) m6A 3'UTR       24981863
chr2:85546493-85546494(-) m6A 3'UTR       24209618
chr2:85546516-85546517(-) m6A 3'UTR       24209618
chr2:85547023-85547024(-) m6A 3'UTR       24284625
chr2:85547034-85547035(-) m6A 3'UTR       24284625
chr2:85547623-85547624(-) m6A 3'UTR       27773535
chr2:85547656-85547657(-) m6A 3'UTR       27773535
chr2:85548292-85548293(-) m6A 3'UTR       24284625//24981863//27773535
chr2:85549101-85549102(-) m6A 3'UTR       27773535
chr2:85549106-85549107(-) m6A 3'UTR       27773535
chr2:85549147-85549148(-) m6A 3'UTR       27773535
chr2:85549243-85549244(-) m6A 3'UTR       24284625//24981863//26404942//27773535
chr2:85549249-85549250(-) m6A 3'UTR       24284625//24981863//26404942//27773535
chr2:85549262-85549263(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//27371828//22608085
chr2:85549326-85549327(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr2:85549390-85549391(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr2:85549402-85549403(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr2:85549534-85549535(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr2:85549700-85549701(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr2:85549769-85549770(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr2:85552044-85552045(-) m6A CDS       24284625
chr2:85553782-85553783(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22608085
chr2:85553793-85553794(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22608085
chr2:85553858-85553859(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22608085
chr2:85553950-85553951(-) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//27371828//22608085
chr2:85553968-85553969(-) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//27371828//22608085
chr2:85554012-85554013(-) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//27371828//22608085
chr2:85554072-85554073(-) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//27371828//22608085
chr2:85554114-85554115(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//27371828//22608085
chr2:85554124-85554125(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//27371828//22608085
chr2:85554208-85554209(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr2:85554250-85554251(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr2:85554292-85554293(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr2:85554334-85554335(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr2:85554366-85554367(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr2:85554376-85554377(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr2:85554408-85554409(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr2:85554418-85554419(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr2:85554450-85554451(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr2:85554460-85554461(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr2:85554492-85554493(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr2:85554502-85554503(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr2:85554544-85554545(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr2:85554576-85554577(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr2:85554586-85554587(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr2:85554618-85554619(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr2:85554628-85554629(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr2:85554660-85554661(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr2:85554670-85554671(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr2:85554765-85554766(-) m1A CDS       26863196
chr2:85555151-85555152(-) m6A 5'UTR       25456834//24981863//27371828//27773536
chr2:85555179-85555180(-) m6A 5'UTR       24981863//27371828
chr2:85555287-85555288(-) m1A 5'UTR       26863196
chr2:85555296-85555297(-) m6A 5'UTR       24209618//24981863//27371828
chr2:85555324-85555325(-) m6A 5'UTR       24981863//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-128-2-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
TGOLN2
Chromatin K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-128-2-5p
Interactor2: TGOLN2

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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