Detail Information

Basic Information:


  VIRBase ID:  

HHID00075331

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-128-1-5p:           SEMA7A:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-128-1-5p SEMA7A
miRBase
Accession/Entrez ID		 MIMAT0026477 8482
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CD108//CDw108//H-SEMA-K1//H-Sema-L//JMH//SEMAK1//SEMAL

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-128-1-5p
rs1421580157 chr2:135665426    G/C
rs1484545550 chr2:135665425    T/C
rs759451365 chr2:135665421    G/A
rs762767177 chr2:135665411    C/T
rs117812383 chr2:135665418    G/A
rs1258427834 chr2:135665412    G/A
rs1258427834 chr2:135665412    G/C
rs1258427834 chr2:135665412    G/T
rs368374639 chr2:135665414    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SEMA7A
chr15:74713512(-) A-I      intronic
chr15:74719849(-) A-I      intronic
chr15:74719918(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SEMA7A
chr15:74701854-74701855(-) m6A 3'UTR       26404942
chr15:74701875-74701876(-) m6A 3'UTR       26404942
chr15:74702301-74702302(-) m6A 3'UTR       26404942
chr15:74702429-74702430(-) m6A 3'UTR       24209618//25456834
chr15:74702495-74702496(-) m6A 3'UTR       24209618//25456834//28052920//27371828
chr15:74702562-74702563(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27371828//22575960//22608085
chr15:74702603-74702604(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr15:74702678-74702679(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr15:74702687-74702688(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr15:74702715-74702716(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr15:74702852-74702853(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27371828//22608085
chr15:74703289-74703290(-) m6A CDS       -
chr15:74703325-74703326(-) m6A CDS//exon       -
chr15:74703387-74703388(-) m6A exon//intron       -
chr15:74703639-74703640(-) m6A CDS//exon       -
chr15:74703932-74703933(-) m6A CDS//exon       -
chr15:74703950-74703951(-) m6A CDS//exon       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-128-1-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
SEMA7A
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-128-1-5p
Interactor2: SEMA7A

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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