Detail Information

Basic Information:


  VIRBase ID:  

HHID00075059

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-365b-5p:           ATP13A3:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-365b-5p ATP13A3
miRBase
Accession/Entrez ID		 MIMAT0022833 79572
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - AFURS1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-365b-5p
rs367566254 chr17:31575447    T/C
rs374487127 chr17:31575456    G/A
rs752977263 chr17:31575459    G/A
rs752977263 chr17:31575459    G/C
rs755134697 chr17:31575448    C/T
rs767877480 chr17:31575457    CTG/C
rs889256848 chr17:31575450    G/A
rs1245222811 chr17:31575440    G/A
rs1315675828 chr17:31575442    G/A
rs759650574 chr17:31575439    AG/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ATP13A3
chr3:194192271(-) A-I      intronic
chr3:194138638(-) A-I      intronic
chr3:194184723(-) A-I      intronic
chr3:194184807(-) A-I      intronic
chr3:194203068(-) A-I      intronic
chr3:194203072(-) A-I      intronic
chr3:194203445(-) A-I      intronic
chr3:194203736(-) A-I      intronic
chr3:194204062(-) A-I      intronic
chr3:194204068(-) A-I      intronic
chr3:194204098(-) A-I      intronic
chr3:194185619(-) A-I      intronic
chr3:194187497(-) A-I      intronic
chr3:194192180(-) A-I      intronic
chr3:194192207(-) A-I      intronic
chr3:194192227(-) A-I      intronic
chr3:194192231(-) A-I      intronic
chr3:194192276(-) A-I      intronic
chr3:194203029(-) A-I      intronic
chr3:194203049(-) A-I      intronic
chr3:194129045(-) A-I      intronic
chr3:194205678(-) A-I      intronic
chr3:194127024(-) A-I      intronic
chr3:194204219(-) A-I      intronic
chr3:194184790(-) A-I      intronic
chr3:194175367(-) A-I      intronic
chr3:194203054(-) A-I      intronic
chr3:194205540(-) A-I      intronic
chr3:194190175(-) A-I      intronic
chr3:194185524(-) A-I      intronic
chr3:194203484(-) A-I      intronic
chr3:194205528(-) A-I      intronic
chr3:194159495(-) A-I      intronic
chr3:194129023(-) A-I      intronic
chr3:194178691(-) A-I      intronic
chr3:194192260(-) A-I      intronic
chr3:194186628(-) A-I      intronic
chr3:194178675(-) A-I      intronic
chr3:194205617(-) A-I      intronic
chr3:194192369(-) A-I      intronic
chr3:194127021(-) A-I      intronic
chr3:194129022(-) A-I      intronic
chr3:194148795(-) A-I      intronic
chr3:194190071(-) A-I      intronic
chr3:194179211(-) A-I      intronic
chr3:194189763(-) A-I      intronic
chr3:194192325(-) A-I      intronic
chr3:194192193(-) A-I      intronic
chr3:194192159(-) A-I      intronic
chr3:194192282(-) A-I      intronic
chr3:194189755(-) A-I      intronic
chr3:194184724(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ATP13A3
chr3:194129045(-) A-I intron -    21960545   //22327324
chr3:194129022(-) A-I intron -    21960545
chr3:194129023(-) A-I intron -    21960545
chr3:194155235(-) A-C intron -    22484847
chr3:194129022(-) A-G intron -    22484847
chr3:194129023(-) A-G intron -    22484847
chr3:194129045(-) A-G intron -    22484847
chr3:194142281(-) G-T intron -    22484847
chr3:194179237(-) T-C intron -    22484847
chr3:194184724(-) A-G intron -    22484847
chr3:194184790(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ATP13A3
chr3:194125092-194125093(-) m6A 3'UTR//exon//intron       26404942
chr3:194125124-194125125(-) m6A 3'UTR//exon//intron       26404942
chr3:194125252-194125253(-) m6A 3'UTR//exon//intron       26404942
chr3:194125261-194125262(-) m6A 3'UTR//exon//intron       26404942
chr3:194126490-194126491(-) m6A 3'UTR//exon//intron       26404942
chr3:194180680-194180681(-) Y CDS       26075521
chr3:194182908-194182909(-) Am CDS       -
chr3:194214877-194214878(-) m6A 5'UTR       -
chr3:194214908-194214909(-) m6A 5'UTR       -
chr3:194218177-194218178(-) m6A intron       24209618
chr3:194218221-194218222(-) m6A intron       24209618
chr3:194218553-194218554(-) m6A intron       24209618
chr3:194218581-194218582(-) m6A 5'UTR       24209618
chr3:194218728-194218729(-) m6A 5'UTR       24209618
chr3:194218782-194218783(-) m6A 5'UTR       24209618
chr3:194218846-194218847(-) m6A 5'UTR       24209618
chr3:194218925-194218926(-) m6A 5'UTR       24209618
chr3:194219061-194219062(-) m6A 5'UTR       24209618

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-365b-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle cells     27563705
ATP13A3
Chromatin K562 cells     -
Cytosol K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells|K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-365b-5p
Interactor2: ATP13A3

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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