Detail Information

Basic Information:


  VIRBase ID:  

HHID00074968

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-365b-5p:           BAG6:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-365b-5p BAG6
miRBase
Accession/Entrez ID		 MIMAT0022833 7917
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - BAG-6//BAT3//D6S52E//G3

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-365b-5p
rs367566254 chr17:31575447    T/C
rs374487127 chr17:31575456    G/A
rs752977263 chr17:31575459    G/A
rs752977263 chr17:31575459    G/C
rs755134697 chr17:31575448    C/T
rs767877480 chr17:31575457    CTG/C
rs889256848 chr17:31575450    G/A
rs1245222811 chr17:31575440    G/A
rs1315675828 chr17:31575442    G/A
rs759650574 chr17:31575439    AG/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR BAG6
chr6:31613849(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase BAG6
chr6:31606968-31606969(-) m6A CDS//exon       27773535
chr6:31607316-31607317(-) m6A CDS//exon//intron       27773535
chr6:31607553-31607554(-) m6A exon//intron       24284625
chr6:31608185-31608186(-) m6A CDS//exon//intron       27773536//22575960
chr6:31608190-31608191(-) m6A CDS//exon//intron       27773536//22575960
chr6:31608212-31608213(-) m6A CDS//exon//intron       27773536//22575960
chr6:31608277-31608278(-) m6A CDS//exon//intron       27773536//22575960
chr6:31608895-31608896(-) Y CDS//exon       26075521
chr6:31609685-31609686(-) m6A CDS//exon       27773535
chr6:31610035-31610036(-) Y CDS//exon       26075521
chr6:31610170-31610171(-) m6A CDS//exon//intron       27773535
chr6:31610883-31610884(-) m6A CDS//exon       24284625//22575960
chr6:31611863-31611864(-) m6A CDS//exon//intron       24284625//22575960
chr6:31611969-31611970(-) m6A CDS//exon//intron       24284625
chr6:31612307-31612308(-) m6A CDS//exon//intron       24284625//27773536
chr6:31612326-31612327(-) m6A CDS//exon//intron       24284625//27773535//27773536
chr6:31612730-31612731(-) m6A CDS//exon       24284625//27773535//22575960
chr6:31612753-31612754(-) m6A CDS//exon       24284625//27773535//22575960
chr6:31612935-31612936(-) m6A CDS//exon       24284625//27773535//22575960
chr6:31612962-31612963(-) m6A CDS//exon       24284625//27773535//22575960
chr6:31614183-31614184(-) m6A CDS       24284625//27773535//22575960
chr6:31615380-31615381(-) m6A CDS       24284625//24981863//27773535//27773536//22575960
chr6:31615433-31615434(-) m6A CDS       24284625//24981863//28052920//27773535//27773536//22575960
chr6:31615507-31615508(-) m6A CDS       24284625//24981863//27773535//22575960
chr6:31615515-31615516(-) m6A CDS       24284625//24981863//27773535//22575960
chr6:31616473-31616474(-) m6A CDS       24284625//27773535
chr6:31616702-31616703(-) m6A CDS//intron       24284625
chr6:31616989-31616990(-) m6A CDS       24284625
chr6:31619458-31619459(-) m6A CDS       24284625
chr6:31619466-31619467(-) m6A CDS       24284625
chr6:31619473-31619474(-) m6A CDS       24284625//22575960
chr6:31619550-31619551(-) m6A 5'UTR       24284625//22575960
chr6:31619650-31619651(-) m6A 5'UTR//intron       24284625
chr6:31619681-31619682(-) m6A 5'UTR//intron       24981863
chr6:31620188-31620189(-) m6A 5'UTR//intron       24284625
chr6:31620275-31620276(-) m6A 5'UTR//intron       24284625//24981863//22575960
chr6:31620312-31620313(-) m6A 5'UTR       24284625//24981863//22575960
chr6:31620333-31620334(-) m6A 5'UTR       24284625//24981863//22575960

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-365b-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle cells     27563705
BAG6
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-365b-5p
Interactor2: BAG6

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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