Detail Information

Basic Information:


  VIRBase ID:  

HHID00074616

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3928-3p:           LACTB2:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3928-3p LACTB2
miRBase
Accession/Entrez ID		 MIMAT0018205 51110
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CGI-83

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3928-3p
rs1005500306 chr22:31160075    G/A
rs1459321820 chr22:31160064    C/G
rs368833031 chr22:31160071    C/CTTTGA
rs60197191 chr22:31160064    C/CAAAGCTCTTTGAAAAGCTGCG
rs879134097 chr22:31160065    G/A
rs879163389 chr22:31160062    G/C
rs890609194 chr22:31160068    G/A
rs908683590 chr22:31160069    C/A
rs940282100 chr22:31160073    A/G
rs1274136392 chr22:31160081    T/C
rs1342810760 chr22:31160076    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR LACTB2
chr8:71551471(-) A-I      intronic
chr8:71552137(-) A-I      intronic
chr8:71551622(-) A-I      intronic
chr8:71551437(-) A-I      intronic
chr8:71562362(-) A-I      intronic
chr8:71556754(-) A-I      intronic
chr8:71556745(-) A-I      intronic
chr8:71551533(-) A-I      intronic
chr8:71551559(-) A-I      intronic
chr8:71556736(-) A-I      intronic
chr8:71552097(-) A-I      intronic
chr8:71556020(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase LACTB2
chr8:71574015-71574016(-) Gm CDS       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3928-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
LACTB2
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3928-3p
Interactor2: LACTB2

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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