Basic Information:

  VIRBase ID:  

HHID00074523

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3150b-3p:  MIMAT0018194          POU2F1:  NR_037163     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3150b-3p	POU2F1
miRBase Accession/Entrez ID	MIMAT0018194	5451
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	oct-1B//OCT1//Oct1Z//OTF1

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3150b-3p	rs886360149 chr8:95072925    C/T rs1256195314 chr8:95072943    C/T rs1484412577 chr8:95072939    T/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	POU2F1	chr1:167202030(+) A-I      intronic chr1:167202473(+) A-I      intronic chr1:167216443(+) A-I      intronic chr1:167238990(+) A-I      intronic chr1:167293033(+) A-I      intronic chr1:167350527(+) A-I      intronic chr1:167208369(+) A-I      intronic chr1:167360411(+) A-I      intronic chr1:167238985(+) A-I      intronic chr1:167391437(+) A-I      3'UTR chr1:167203877(+) A-I      intronic chr1:167203874(+) A-I      intronic chr1:167203828(+) A-I      intronic chr1:167203824(+) A-I      intronic chr1:167346781(+) A-I      intronic chr1:167346776(+) A-I      intronic chr1:167346765(+) A-I      intronic chr1:167209027(+) A-I      intronic chr1:167238991(+) A-I      intronic chr1:167238989(+) A-I      intronic chr1:167203811(+) A-I      intronic chr1:167203810(+) A-I      intronic chr1:167203807(+) A-I      intronic chr1:167360438(+) A-I      intronic chr1:167201904(+) A-I      intronic chr1:167201915(+) A-I      intronic chr1:167201933(+) A-I      intronic chr1:167201949(+) A-I      intronic chr1:167212815(+) A-I      intronic chr1:167254763(+) A-I      intronic chr1:167334068(+) A-I      intronic chr1:167212812(+) A-I      intronic chr1:167267326(+) A-I      intronic chr1:167212806(+) A-I      intronic chr1:167346574(+) A-I      intronic chr1:167212787(+) A-I      intronic chr1:167215014(+) A-I      intronic chr1:167210329(+) A-I      intronic chr1:167346631(+) A-I      intronic chr1:167210300(+) A-I      intronic chr1:167346640(+) A-I      intronic chr1:167222762(+) A-I      intronic chr1:167212987(+) A-I      intronic chr1:167210291(+) A-I      intronic chr1:167269771(+) A-I      intronic chr1:167269782(+) A-I      intronic chr1:167210290(+) A-I      intronic chr1:167269802(+) A-I      intronic chr1:167210227(+) A-I      intronic chr1:167203948(+) A-I      intronic chr1:167202649(+) A-I      intronic chr1:167269841(+) A-I      intronic chr1:167202636(+) A-I      intronic chr1:167212973(+) A-I      intronic chr1:167222756(+) A-I      intronic chr1:167202597(+) A-I      intronic chr1:167202521(+) A-I      intronic chr1:167202515(+) A-I      intronic chr1:167379894(+) A-I      intronic chr1:167333948(+) A-I      intronic chr1:167379892(+) A-I      intronic chr1:167212935(+) A-I      intronic chr1:167212879(+) A-I      intronic chr1:167269868(+) A-I      intronic chr1:167271478(+) A-I      intronic chr1:167271605(+) A-I      intronic chr1:167246543(+) A-I      intronic chr1:167277807(+) A-I      intronic chr1:167374729(+) A-I      intronic chr1:167269867(+) A-I      intronic chr1:167277856(+) A-I      intronic chr1:167277862(+) A-I      intronic chr1:167277892(+) A-I      intronic chr1:167248834(+) A-I      intronic chr1:167333989(+) A-I      intronic chr1:167346669(+) A-I      intronic chr1:167346693(+) A-I      intronic chr1:167346730(+) A-I      intronic chr1:167283216(+) A-I      intronic chr1:167212878(+) A-I      intronic chr1:167333941(+) A-I      intronic chr1:167283224(+) A-I      intronic chr1:167348089(+) A-I      intronic chr1:167220487(+) A-I      intronic chr1:167283232(+) A-I      intronic chr1:167248841(+) A-I      intronic chr1:167379955(+) A-I      intronic chr1:167283250(+) A-I      intronic chr1:167348116(+) A-I      intronic chr1:167283278(+) A-I      intronic chr1:167239031(+) A-I      intronic chr1:167348184(+) A-I      intronic chr1:167348309(+) A-I      intronic chr1:167286209(+) A-I      intronic chr1:167348392(+) A-I      intronic chr1:167293029(+) A-I      intronic chr1:167293030(+) A-I      intronic chr1:167249352(+) A-I      intronic chr1:167360366(+) A-I      intronic chr1:167360439(+) A-I      intronic chr1:167360451(+) A-I      intronic chr1:167360936(+) A-I      intronic chr1:167293059(+) A-I      intronic chr1:167361004(+) A-I      intronic chr1:167361337(+) A-I      intronic chr1:167361385(+) A-I      intronic chr1:167361467(+) A-I      intronic chr1:167374728(+) A-I      intronic chr1:167319837(+) A-I      intronic chr1:167239019(+) A-I      intronic chr1:167319994(+) A-I      intronic chr1:167254750(+) A-I      intronic chr1:167320334(+) A-I      intronic chr1:167320484(+) A-I      intronic chr1:167320488(+) A-I      intronic chr1:167216582(+) A-I      intronic chr1:167254762(+) A-I      intronic chr1:167216517(+) A-I      intronic chr1:167215029(+) A-I      intronic chr1:167326765(+) A-I      intronic chr1:167257806(+) A-I      intronic chr1:167207117(+) A-I      intronic chr1:167348107(+) A-I      intronic chr1:167346709(+) A-I      intronic chr1:167203848(+) A-I      intronic chr1:167376353(+) A-I      intronic chr1:167237060(+) A-I      intronic chr1:167221337(+) A-I      intronic chr1:167268250(+) A-I      intronic chr1:167286352(+) A-I      intronic chr1:167237063(+) A-I      intronic chr1:167306463(+) A-I      intronic chr1:167374810(+) A-I      intronic chr1:167346769(+) A-I      intronic chr1:167220404(+) A-I      intronic chr1:167203714(+) A-I      intronic chr1:167271460(+) A-I      intronic chr1:167348290(+) A-I      intronic chr1:167260040(+) A-I      intronic chr1:167360360(+) A-I      intronic chr1:167221162(+) A-I      intronic chr1:167238892(+) A-I      intronic chr1:167346774(+) A-I      intronic chr1:167350901(+) A-I      intronic chr1:167210165(+) A-I      intronic chr1:167203850(+) A-I      intronic chr1:167260082(+) A-I      intronic chr1:167350449(+) A-I      intronic chr1:167347917(+) A-I      intronic chr1:167201960(+) A-I      intronic chr1:167348353(+) A-I      intronic chr1:167239027(+) A-I      intronic chr1:167346713(+) A-I      intronic chr1:167231023(+) A-I      intronic chr1:167346717(+) A-I      intronic chr1:167360445(+) A-I      intronic chr1:167269750(+) A-I      intronic chr1:167333889(+) A-I      intronic chr1:167210194(+) A-I      intronic chr1:167203857(+) A-I      intronic chr1:167232623(+) A-I      intronic chr1:167259536(+) A-I      intronic chr1:167320689(+) A-I      intronic chr1:167281676(+) A-I      intronic chr1:167201959(+) A-I      intronic chr1:167260184(+) A-I      intronic chr1:167268242(+) A-I      intronic chr1:167249337(+) A-I      intronic chr1:167212497(+) A-I      intronic chr1:167237084(+) A-I      intronic chr1:167274572(+) A-I      intronic chr1:167281599(+) A-I      intronic chr1:167211178(+) A-I      intronic chr1:167355658(+) A-I      intronic chr1:167376415(+) A-I      intronic chr1:167293144(+) A-I      intronic chr1:167268240(+) A-I      intronic chr1:167320493(+) A-I      intronic chr1:167210125(+) A-I      intronic chr1:167360961(+) A-I      intronic chr1:167347843(+) A-I      intronic chr1:167277939(+) A-I      intronic chr1:167333995(+) A-I      intronic chr1:167348273(+) A-I      intronic chr1:167374778(+) A-I      intronic chr1:167207193(+) A-I      intronic chr1:167360860(+) A-I      intronic chr1:167348115(+) A-I      intronic chr1:167281586(+) A-I      intronic chr1:167268186(+) A-I      intronic chr1:167348422(+) A-I      intronic chr1:167208982(+) A-I      intronic chr1:167260189(+) A-I      intronic chr1:167227106(+) A-I      intronic chr1:167346569(+) A-I      intronic chr1:167344157(+) A-I      intronic chr1:167294979(+) A-I      intronic chr1:167208978(+) A-I      intronic chr1:167346703(+) A-I      intronic chr1:167374802(+) A-I      intronic chr1:167374713(+) A-I      intronic chr1:167202486(+) A-I      intronic chr1:167360951(+) A-I      intronic chr1:167201957(+) A-I      intronic chr1:167211221(+) A-I      intronic chr1:167361332(+) A-I      intronic chr1:167209078(+) A-I      intronic chr1:167309755(+) A-I      intronic chr1:167220506(+) A-I      intronic chr1:167270147(+) A-I      intronic chr1:167361468(+) A-I      intronic chr1:167374657(+) A-I      intronic chr1:167211170(+) A-I      intronic chr1:167283181(+) A-I      intronic chr1:167315265(+) A-I      intronic chr1:167325249(+) A-I      intronic chr1:167202610(+) A-I      intronic chr1:167346568(+) A-I      intronic chr1:167211220(+) A-I      intronic chr1:167267295(+) A-I      intronic chr1:167361043(+) A-I      intronic chr1:167231061(+) A-I      intronic chr1:167220529(+) A-I      intronic chr1:167264237(+) A-I      intronic chr1:167320190(+) A-I      intronic chr1:167376488(+) A-I      intronic chr1:167274590(+) A-I      intronic chr1:167347864(+) A-I      intronic chr1:167347529(+) A-I      intronic chr1:167361005(+) A-I      intronic chr1:167320375(+) A-I      intronic chr1:167220502(+) A-I      intronic chr1:167212564(+) A-I      intronic chr1:167208985(+) A-I      intronic chr1:167208259(+) A-I      intronic chr1:167239029(+) A-I      intronic chr1:167259622(+) A-I      intronic chr1:167259511(+) A-I      intronic chr1:167359753(+) A-I      intronic chr1:167320706(+) A-I      intronic chr1:167271389(+) A-I      intronic chr1:167207199(+) A-I      intronic chr1:167347826(+) A-I      intronic chr1:167361530(+) A-I      intronic chr1:167249296(+) A-I      intronic chr1:167216413(+) A-I      intronic chr1:167348431(+) A-I      intronic chr1:167270107(+) A-I      intronic chr1:167374804(+) A-I      intronic chr1:167239071(+) A-I      intronic chr1:167347863(+) A-I      intronic chr1:167259513(+) A-I      intronic chr1:167221137(+) A-I      intronic chr1:167347852(+) A-I      intronic chr1:167281602(+) A-I      intronic chr1:167374733(+) A-I      intronic chr1:167212539(+) A-I      intronic chr1:167348094(+) A-I      intronic chr1:167203787(+) A-I      intronic chr1:167283219(+) A-I      intronic chr1:167361331(+) A-I      intronic chr1:167267147(+) A-I      intronic chr1:167376469(+) A-I      intronic chr1:167374660(+) A-I      intronic chr1:167383203(+) A-I      intronic chr1:167244498(+) A-I      intronic chr1:167344193(+) A-I      intronic chr1:167270120(+) A-I      intronic chr1:167270125(+) A-I      intronic chr1:167249320(+) A-I      intronic chr1:167238988(+) A-I      intronic chr1:167376407(+) A-I      intronic chr1:167333512(+) A-I      intronic chr1:167394442(+) A-I      3'UTR

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	POU2F1	chr1:167385287(+) A-I exon 3'UTR    15342557 chr1:167385299(+) A-I exon 3'UTR    15342557 chr1:167385306(+) A-I exon 3'UTR    15342557 chr1:167211170(+) A-I intron -    21960545 chr1:167212497(+) A-I intron -    21960545 chr1:167212538(+) A-I intron -    21960545 chr1:167212539(+) A-I intron -    21960545 chr1:167201957(+) A-G intron -    22484847 chr1:167201959(+) A-G intron -    22484847 chr1:167201960(+) A-G intron -    22484847 chr1:167202486(+) A-G intron -    22484847 chr1:167203714(+) A-G intron -    22484847 chr1:167210125(+) A-G intron -    22484847 chr1:167220404(+) A-G intron -    22484847 chr1:167220502(+) A-G intron -    22484847 chr1:167220506(+) A-G intron -    22484847 chr1:167220529(+) A-G intron -    22484847 chr1:167221162(+) A-G intron -    22484847 chr1:167221337(+) A-G intron -    22484847 chr1:167260184(+) A-G intron -    22484847 chr1:167267295(+) A-G intron -    22484847 chr1:167269750(+) A-G intron -    22484847 chr1:167271460(+) A-G intron -    22484847 chr1:167281599(+) A-G intron -    22484847 chr1:167281602(+) A-G intron -    22484847 chr1:167294979(+) A-G intron -    22484847 chr1:167309379(+) C-T intron -    22484847 chr1:167325249(+) A-G intron -    22484847 chr1:167333889(+) A-G intron -    22484847 chr1:167333995(+) A-G intron -    22484847 chr1:167346703(+) A-G intron -    22484847 chr1:167346709(+) A-G intron -    22484847 chr1:167346717(+) A-G intron -    22484847 chr1:167347545(+) C-T intron -    22484847 chr1:167347826(+) A-G intron -    22484847 chr1:167347843(+) A-G intron -    22484847 chr1:167347852(+) A-G intron -    22484847 chr1:167347863(+) A-G intron -    22484847 chr1:167348107(+) A-G intron -    22484847 chr1:167348115(+) A-G intron -    22484847 chr1:167348273(+) A-G intron -    22484847 chr1:167348290(+) A-G intron -    22484847 chr1:167348422(+) A-G intron -    22484847 chr1:167350449(+) A-G intron -    22484847 chr1:167360360(+) A-G intron -    22484847 chr1:167360445(+) A-G intron -    22484847 chr1:167360860(+) A-G intron -    22484847 chr1:167361005(+) A-G intron -    22484847 chr1:167361332(+) A-G intron -    22484847 chr1:167369296(+) C-T intron -    22484847 chr1:167369323(+) C-T intron -    22484847 chr1:167389494(+) G-A intron -    22484847 chr1:167211170(+) A-G intron -    22484847 chr1:167211221(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	POU2F1	chr1:167210660-167210661(+) m6A exon//intron       24284625//24981863 chr1:167298522-167298523(+) m6A CDS//intron       24981863 chr1:167301718-167301719(+) m6A 3'UTR//CDS//exon       24981863 chr1:167301732-167301733(+) m6A 3'UTR//CDS//exon       24981863 chr1:167301740-167301741(+) m6A 3'UTR//CDS//exon       24981863 chr1:167307211-167307212(+) m6A exon//intron       24981863 chr1:167307256-167307257(+) m1A exon//intron       26863196 chr1:167345797-167345798(+) m6A exon//intron       - chr1:167345812-167345813(+) m6A exon//intron       - chr1:167358866-167358867(+) m6A 3'UTR//CDS//exon//intron       24284625//24981863 chr1:167358959-167358960(+) m6A 3'UTR//CDS//exon//intron       24981863 chr1:167368554-167368555(+) m6A 3'UTR//CDS//exon       - chr1:167381204-167381205(+) m6A 3'UTR//CDS//exon       24284625 chr1:167381335-167381336(+) m6A 3'UTR//CDS//exon       24284625//24981863 chr1:167381350-167381351(+) m6A 3'UTR//CDS//exon       24284625 chr1:167381383-167381384(+) m6A 3'UTR//CDS//exon       24284625 chr1:167381419-167381420(+) m6A 3'UTR//CDS//exon       24284625 chr1:167381499-167381500(+) m6A 3'UTR//CDS//exon       24284625 chr1:167381504-167381505(+) m6A 3'UTR//CDS//exon       24284625 chr1:167382290-167382291(+) m6A 3'UTR//CDS//exon       24284625 chr1:167384787-167384788(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//24981863//22608085 chr1:167384847-167384848(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//22608085 chr1:167384856-167384857(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//22608085 chr1:167384919-167384920(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//22608085 chr1:167384976-167384977(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//22608085 chr1:167385099-167385100(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr1:167385119-167385120(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr1:167385192-167385193(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr1:167385246-167385247(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr1:167385270-167385271(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//27773535//22608085 chr1:167385306-167385307(+) m6A 3'UTR//CDS//exon       24284625//25456834//24981863//27773535//22608085 chr1:167385346-167385347(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr1:167385361-167385362(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr1:167385383-167385384(+) m6A 3'UTR//exon       24981863//27773535//22608085 chr1:167392787-167392788(+) m6A 3'UTR//exon       - chr1:167392802-167392803(+) m6A 3'UTR//exon       - chr1:167392899-167392900(+) m6A 3'UTR//exon       - chr1:167392906-167392907(+) m6A 3'UTR//exon       - chr1:167392925-167392926(+) m6A 3'UTR//exon       - chr1:167394552-167394553(+) m6A 3'UTR//exon       24981863 chr1:167394641-167394642(+) m6A 3'UTR//exon       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3150b-3p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	POU2F1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Membrane HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3150b-3p
Interactor2: POU2F1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.