Detail Information

Basic Information:


  VIRBase ID:  

HHID00074308

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3682-3p:           PPP1R3B:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3682-3p PPP1R3B
miRBase
Accession/Entrez ID		 MIMAT0018110 79660
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - GL//PPP1R4//PTG

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3682-3p
rs1054334622 chr2:53849141    T/G
rs1294406945 chr2:53849146    C/T
rs1342831019 chr2:53849145    C/A
rs1409713352 chr2:53849148    G/A
rs184679526 chr2:53849139    C/T
rs893651893 chr2:53849143    C/T
rs1348115721 chr2:53849149    TATC/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PPP1R3B
chr8:9001009(-) A-I      intronic
chr8:9001125(-) A-I      intronic
chr8:8999767(-) A-I      intronic
chr8:9001126(-) A-I      intronic
chr8:8999775(-) A-I      intronic
chr8:9001200(-) A-I      intronic
chr8:9001202(-) A-I      intronic
chr8:9001204(-) A-I      intronic
chr8:8999766(-) A-I      intronic
chr8:9002372(-) A-I      intronic
chr8:9001136(-) A-I      intronic
chr8:9001130(-) A-I      intronic
chr8:9001082(-) A-I      intronic
chr8:8999808(-) A-I      intronic
chr8:8999806(-) A-I      intronic
chr8:8999774(-) A-I      intronic
chr8:8999771(-) A-I      intronic
chr8:9001008(-) A-I      intronic
chr8:9001112(-) A-I      intronic
chr8:8996557(-) A-I      3'UTR
chr8:8997119(-) A-I      3'UTR
chr8:8997130(-) A-I      3'UTR
chr8:8997131(-) A-I      3'UTR
chr8:8996491(-) A-I      3'UTR
chr8:8997137(-) A-I      3'UTR
chr8:8997097(-) A-I      3'UTR
chr8:8996683(-) A-I      3'UTR
chr8:8996603(-) A-I      3'UTR
chr8:9003508(-) A-I      intronic
chr8:9001046(-) A-I      intronic
chr8:8996605(-) A-I      3'UTR
chr8:8996722(-) A-I      3'UTR
chr8:9004601(-) A-I      intronic
chr8:9001027(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PPP1R3B
chr8:8993769-8993770(-) m6A 3'UTR       27773535
chr8:8993774-8993775(-) m6A 3'UTR       27773535
chr8:8993956-8993957(-) m6A 3'UTR       24981863//27773535
chr8:8993963-8993964(-) m6A 3'UTR       24981863//27773535
chr8:8994028-8994029(-) m6A 3'UTR       24981863//27773535//22608085
chr8:8994036-8994037(-) m6A 3'UTR       24981863//27773535//22608085
chr8:8994140-8994141(-) m6A 3'UTR       24209618//25456834//24981863//27773535//27371828//22608085
chr8:8994150-8994151(-) m6A 3'UTR       24209618//25456834//24981863//27773535//27371828//22608085
chr8:8994164-8994165(-) m6A 3'UTR       24209618//25456834//24981863//27773535//27371828//22608085
chr8:8994200-8994201(-) m6A 3'UTR       24209618//25456834//24981863//27773535//27371828//22608085
chr8:8994245-8994246(-) m6A 3'UTR       25456834//24981863//27371828//22608085
chr8:8995260-8995261(-) m6A 3'UTR       27773535
chr8:8995281-8995282(-) m6A 3'UTR       24284625//27773535
chr8:8995422-8995423(-) m6A 3'UTR       27773535
chr8:8995489-8995490(-) m6A 3'UTR       27773535
chr8:8995677-8995678(-) m6A 3'UTR       24981863
chr8:8995694-8995695(-) m6A 3'UTR       24981863
chr8:8995715-8995716(-) m6A 3'UTR       24981863
chr8:8996402-8996403(-) m6A 3'UTR       25456834//24981863//27773535//27371828
chr8:8996427-8996428(-) m6A 3'UTR       25456834//24981863//27773535//27371828
chr8:8996436-8996437(-) m6A 3'UTR       25456834//24981863//27773535//27371828
chr8:8996455-8996456(-) m6A 3'UTR       25456834//24981863//27773535//27371828
chr8:8996524-8996525(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085
chr8:8996620-8996621(-) m6A 3'UTR       24209618//25456834//24981863//27773535//22608085
chr8:8996643-8996644(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr8:8996734-8996735(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr8:8996769-8996770(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr8:8996851-8996852(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr8:8996901-8996902(-) m6A 3'UTR       24209618//24981863//27773535//22575960//22608085
chr8:8996907-8996908(-) m6A 3'UTR       24209618//24981863//27773535//22575960//22608085
chr8:8996928-8996929(-) m6A 3'UTR       24209618//24981863//27773535//22575960//22608085
chr8:8996975-8996976(-) m6A 3'UTR       24284625//24209618//24981863//27773535//27371828//22608085
chr8:8997008-8997009(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr8:8997073-8997074(-) m6A 3'UTR       24209618//25456834//24981863//27773535//27371828//22608085
chr8:8997085-8997086(-) m6A 3'UTR       24209618//25456834//24981863//27773535//27371828//22608085
chr8:8997129-8997130(-) m6A 3'UTR       24209618//25456834//24981863//27773535//27371828//22608085
chr8:8997154-8997155(-) m6A 3'UTR       24209618//25456834//24981863//27371828
chr8:8997253-8997254(-) m6A 3'UTR       24209618//24981863
chr8:8997276-8997277(-) m6A 3'UTR       24209618//24981863
chr8:8997510-8997511(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085
chr8:8997526-8997527(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085
chr8:8997578-8997579(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr8:8997651-8997652(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr8:8997905-8997906(-) m6A 3'UTR       24284625//25456834//24981863//27371828//22608085
chr8:8997950-8997951(-) m6A 3'UTR       24284625//25456834//27371828//22608085
chr8:8998149-8998150(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr8:8998205-8998206(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr8:8998265-8998266(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr8:8998414-8998415(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr8:8998475-8998476(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr8:8998493-8998494(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr8:8998507-8998508(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr8:8998592-8998593(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr8:8998598-8998599(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr8:8998616-8998617(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr8:8998640-8998641(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr8:8998686-8998687(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr8:8998703-8998704(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr8:8998736-8998737(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr8:8998751-8998752(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr8:8998793-8998794(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr8:8998871-8998872(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr8:8998961-8998962(-) m6A CDS       27773535
chr8:8999065-8999066(-) m6A CDS       27773535
chr8:8999147-8999148(-) m6A CDS       24981863
chr8:9008167-9008168(-) m6A 5'UTR//intron       24981863//27371828
chr8:9008192-9008193(-) m6A 5'UTR//intron       24981863//27371828
chr8:9008860-9008861(-) m6A 5'UTR       24981863//27371828//27773536
chr8:9008873-9008874(-) m6A 5'UTR       27773536
chr8:9008965-9008966(-) m6A 5'UTR       24981863//27773536
chr8:9008990-9008991(-) m6A 5'UTR       24981863//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3682-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
PPP1R3B
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3682-3p
Interactor2: PPP1R3B

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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