Basic Information:

  VIRBase ID:  

HHID00074295

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3682-3p:  MIMAT0018110          FBXW11:  NM_001378980     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3682-3p	FBXW11
miRBase Accession/Entrez ID	MIMAT0018110	23291
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	BTRC2//BTRCP2//Fbw11//FBW1B//FBXW1B//Hos//NEDJED

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3682-3p	rs1054334622 chr2:53849141    T/G rs1294406945 chr2:53849146    C/T rs1342831019 chr2:53849145    C/A rs1409713352 chr2:53849148    G/A rs184679526 chr2:53849139    C/T rs893651893 chr2:53849143    C/T rs1348115721 chr2:53849149    TATC/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FBXW11	chr5:171350112(-) A-I      intronic chr5:171350106(-) A-I      intronic chr5:171429870(-) A-I      intronic chr5:171396913(-) A-I      intronic chr5:171374107(-) A-I      intronic chr5:171373998(-) A-I      intronic chr5:171396877(-) A-I      intronic chr5:171350100(-) A-I      intronic chr5:171350097(-) A-I      intronic chr5:171350096(-) A-I      intronic chr5:171429882(-) A-I      intronic chr5:171399033(-) A-I      intronic chr5:171399019(-) A-I      intronic chr5:171399018(-) A-I      intronic chr5:171399015(-) A-I      intronic chr5:171399014(-) A-I      intronic chr5:171398990(-) A-I      intronic chr5:171398770(-) A-I      intronic chr5:171396981(-) A-I      intronic chr5:171374042(-) A-I      intronic chr5:171396979(-) A-I      intronic chr5:171387302(-) A-I      intronic chr5:171373989(-) A-I      intronic chr5:171365348(-) A-I      intronic chr5:171365291(-) A-I      intronic chr5:171378440(-) A-I      intronic chr5:171365269(-) A-I      intronic chr5:171365183(-) A-I      intronic chr5:171365165(-) A-I      intronic chr5:171365164(-) A-I      intronic chr5:171365159(-) A-I      intronic chr5:171365091(-) A-I      intronic chr5:171364756(-) A-I      intronic chr5:171364750(-) A-I      intronic chr5:171364732(-) A-I      intronic chr5:171331847(-) A-I      intronic chr5:171364648(-) A-I      intronic chr5:171362166(-) A-I      intronic chr5:171362156(-) A-I      intronic chr5:171362122(-) A-I      intronic chr5:171362118(-) A-I      intronic chr5:171362050(-) A-I      intronic chr5:171359154(-) A-I      intronic chr5:171359116(-) A-I      intronic chr5:171359056(-) A-I      intronic chr5:171399265(-) A-I      intronic chr5:171399136(-) A-I      intronic chr5:171359043(-) A-I      intronic chr5:171378465(-) A-I      intronic chr5:171378479(-) A-I      intronic chr5:171380066(-) A-I      intronic chr5:171429849(-) A-I      intronic chr5:171429841(-) A-I      intronic chr5:171429827(-) A-I      intronic chr5:171429794(-) A-I      intronic chr5:171425765(-) A-I      intronic chr5:171425701(-) A-I      intronic chr5:171425411(-) A-I      intronic chr5:171423620(-) A-I      intronic chr5:171423539(-) A-I      intronic chr5:171421985(-) A-I      intronic chr5:171419349(-) A-I      intronic chr5:171419348(-) A-I      intronic chr5:171419344(-) A-I      intronic chr5:171419336(-) A-I      intronic chr5:171419320(-) A-I      intronic chr5:171419284(-) A-I      intronic chr5:171419283(-) A-I      intronic chr5:171419266(-) A-I      intronic chr5:171418118(-) A-I      intronic chr5:171352582(-) A-I      intronic chr5:171418094(-) A-I      intronic chr5:171418062(-) A-I      intronic chr5:171418057(-) A-I      intronic chr5:171399105(-) A-I      intronic chr5:171418012(-) A-I      intronic chr5:171417978(-) A-I      intronic chr5:171416119(-) A-I      intronic chr5:171399044(-) A-I      intronic chr5:171377646(-) A-I      intronic chr5:171350121(-) A-I      intronic chr5:171331668(-) A-I      intronic chr5:171331261(-) A-I      intronic chr5:171331242(-) A-I      intronic chr5:171396876(-) A-I      intronic chr5:171396791(-) A-I      intronic chr5:171396772(-) A-I      intronic chr5:171396124(-) A-I      intronic chr5:171331138(-) A-I      intronic chr5:171331127(-) A-I      intronic chr5:171396123(-) A-I      intronic chr5:171394647(-) A-I      intronic chr5:171388824(-) A-I      intronic chr5:171388788(-) A-I      intronic chr5:171399722(-) A-I      intronic chr5:171388762(-) A-I      intronic chr5:171330193(-) A-I      intronic chr5:171314826(-) A-I      intronic chr5:171314799(-) A-I      intronic chr5:171313979(-) A-I      intronic chr5:171380079(-) A-I      intronic chr5:171330801(-) A-I      intronic chr5:171330778(-) A-I      intronic chr5:171379658(-) A-I      intronic chr5:171378754(-) A-I      intronic chr5:171373996(-) A-I      intronic chr5:171378668(-) A-I      intronic chr5:171378632(-) A-I      intronic chr5:171377673(-) A-I      intronic chr5:171377655(-) A-I      intronic chr5:171374031(-) A-I      intronic chr5:171374845(-) A-I      intronic chr5:171373987(-) A-I      intronic chr5:171364770(-) A-I      intronic chr5:171364763(-) A-I      intronic chr5:171348998(-) A-I      intronic chr5:171348991(-) A-I      intronic chr5:171348989(-) A-I      intronic chr5:171416112(-) A-I      intronic chr5:171416099(-) A-I      intronic chr5:171416098(-) A-I      intronic chr5:171415766(-) A-I      intronic chr5:171415727(-) A-I      intronic chr5:171415721(-) A-I      intronic chr5:171415646(-) A-I      intronic chr5:171413393(-) A-I      intronic chr5:171413329(-) A-I      intronic chr5:171413300(-) A-I      intronic chr5:171413290(-) A-I      intronic chr5:171413280(-) A-I      intronic chr5:171412545(-) A-I      intronic chr5:171412437(-) A-I      intronic chr5:171409546(-) A-I      intronic chr5:171409448(-) A-I      intronic chr5:171406177(-) A-I      intronic chr5:171406176(-) A-I      intronic chr5:171402048(-) A-I      intronic chr5:171401661(-) A-I      intronic chr5:171401653(-) A-I      intronic chr5:171313897(-) A-I      intronic chr5:171399844(-) A-I      intronic chr5:171399830(-) A-I      intronic chr5:171399816(-) A-I      intronic chr5:171399805(-) A-I      intronic chr5:171399742(-) A-I      intronic chr5:171399737(-) A-I      intronic chr5:171399731(-) A-I      intronic chr5:171399728(-) A-I      intronic chr5:171399725(-) A-I      intronic chr5:171399719(-) A-I      intronic chr5:171399717(-) A-I      intronic chr5:171399713(-) A-I      intronic chr5:171399709(-) A-I      intronic chr5:171399687(-) A-I      intronic chr5:171399677(-) A-I      intronic chr5:171399655(-) A-I      intronic chr5:171399467(-) A-I      intronic chr5:171399279(-) A-I      intronic chr5:171359082(-) A-I      intronic chr5:171399001(-) A-I      intronic chr5:171314683(-) A-I      intronic chr5:171369559(-) A-I      intronic chr5:171423559(-) A-I      intronic chr5:171377791(-) A-I      intronic chr5:171416167(-) A-I      intronic chr5:171402025(-) A-I      intronic chr5:171331223(-) A-I      intronic chr5:171378497(-) A-I      intronic chr5:171352482(-) A-I      intronic chr5:171370600(-) A-I      intronic chr5:171378508(-) A-I      intronic chr5:171374754(-) A-I      intronic chr5:171418048(-) A-I      intronic chr5:171351022(-) A-I      intronic chr5:171309378(-) A-I      intronic chr5:171344053(-) A-I      intronic chr5:171388742(-) A-I      intronic chr5:171425598(-) A-I      intronic chr5:171395375(-) A-I      intronic chr5:171410112(-) A-I      intronic chr5:171378391(-) A-I      intronic chr5:171429923(-) A-I      intronic chr5:171379595(-) A-I      intronic chr5:171425556(-) A-I      intronic chr5:171362061(-) A-I      intronic chr5:171347550(-) A-I      intronic chr5:171410188(-) A-I      intronic chr5:171369770(-) A-I      intronic chr5:171417967(-) A-I      intronic chr5:171423545(-) A-I      intronic chr5:171398814(-) A-I      intronic chr5:171378322(-) A-I      intronic chr5:171374890(-) A-I      intronic chr5:171358981(-) A-I      intronic chr5:171314919(-) A-I      intronic chr5:171414694(-) A-I      intronic chr5:171331704(-) A-I      intronic chr5:171409471(-) A-I      intronic chr5:171420505(-) A-I      intronic chr5:171373997(-) A-I      intronic chr5:171406238(-) A-I      intronic chr5:171401247(-) A-I      intronic chr5:171421898(-) A-I      intronic chr5:171331109(-) A-I      intronic chr5:171414660(-) A-I      intronic chr5:171348811(-) A-I      intronic chr5:171401611(-) A-I      intronic chr5:171396150(-) A-I      intronic chr5:171378763(-) A-I      intronic chr5:171416059(-) A-I      intronic chr5:171401901(-) A-I      intronic chr5:171365134(-) A-I      intronic chr5:171331135(-) A-I      intronic chr5:171361498(-) A-I      intronic chr5:171414729(-) A-I      intronic chr5:171401997(-) A-I      intronic chr5:171425633(-) A-I      intronic chr5:171378368(-) A-I      intronic chr5:171377815(-) A-I      intronic chr5:171359074(-) A-I      intronic chr5:171379627(-) A-I      intronic chr5:171331268(-) A-I      intronic chr5:171396852(-) A-I      intronic chr5:171429885(-) A-I      intronic chr5:171398769(-) A-I      intronic chr5:171429843(-) A-I      intronic chr5:171396845(-) A-I      intronic chr5:171417941(-) A-I      intronic chr5:171401640(-) A-I      intronic chr5:171379594(-) A-I      intronic chr5:171378665(-) A-I      intronic chr5:171399686(-) A-I      intronic chr5:171359861(-) A-I      intronic chr5:171401236(-) A-I      intronic chr5:171418023(-) A-I      intronic chr5:171396908(-) A-I      intronic chr5:171398794(-) A-I      intronic chr5:171375479(-) A-I      intronic chr5:171379626(-) A-I      intronic chr5:171317306(-) A-I      intronic chr5:171418102(-) A-I      intronic chr5:171331846(-) A-I      intronic chr5:171314856(-) A-I      intronic chr5:171412411(-) A-I      intronic chr5:171399264(-) A-I      intronic chr5:171374424(-) A-I      intronic chr5:171374864(-) A-I      intronic chr5:171401654(-) A-I      intronic chr5:171399743(-) A-I      intronic chr5:171374838(-) A-I      intronic chr5:171401966(-) A-I      intronic chr5:171305553(-) A-I      intronic chr5:171373956(-) A-I      intronic chr5:171415677(-) A-I      intronic chr5:171374485(-) A-I      intronic chr5:171378323(-) A-I      intronic chr5:171331714(-) A-I      intronic chr5:171331189(-) A-I      intronic chr5:171401937(-) A-I      intronic chr5:171377860(-) A-I      intronic chr5:171331097(-) A-I      intronic chr5:171395271(-) A-I      intronic chr5:171425452(-) A-I      intronic chr5:171331044(-) A-I      intronic chr5:171347575(-) A-I      intronic chr5:171330147(-) A-I      intronic chr5:171337207(-) A-I      intronic chr5:171331050(-) A-I      intronic chr5:171374446(-) A-I      intronic chr5:171380232(-) A-I      intronic chr5:171331841(-) A-I      intronic chr5:171415787(-) A-I      intronic chr5:171361489(-) A-I      intronic chr5:171429956(-) A-I      intronic chr5:171374765(-) A-I      intronic chr5:171331216(-) A-I      intronic chr5:171314800(-) A-I      intronic chr5:171386816(-) A-I      intronic chr5:171419369(-) A-I      intronic chr5:171347558(-) A-I      intronic chr5:171374113(-) A-I      intronic chr5:171359151(-) A-I      intronic chr5:171386601(-) A-I      intronic chr5:171365130(-) A-I      intronic chr5:171418111(-) A-I      intronic chr5:171417990(-) A-I      intronic chr5:171375497(-) A-I      intronic chr5:171314679(-) A-I      intronic chr5:171396241(-) A-I      intronic chr5:171364583(-) A-I      intronic chr5:171374021(-) A-I      intronic chr5:171337357(-) A-I      intronic chr5:171348939(-) A-I      intronic chr5:171429857(-) A-I      intronic chr5:171377779(-) A-I      intronic chr5:171410186(-) A-I      intronic chr5:171374064(-) A-I      intronic chr5:171305514(-) A-I      intronic chr5:171378428(-) A-I      intronic chr5:171425451(-) A-I      intronic chr5:171425435(-) A-I      intronic chr5:171394699(-) A-I      intronic chr5:171378770(-) A-I      intronic chr5:171414593(-) A-I      intronic chr5:171412650(-) A-I      intronic chr5:171419331(-) A-I      intronic chr5:171331056(-) A-I      intronic chr5:171409526(-) A-I      intronic chr5:171378633(-) A-I      intronic chr5:171399064(-) A-I      intronic chr5:171398742(-) A-I      intronic chr5:171380216(-) A-I      intronic chr5:171429911(-) A-I      intronic chr5:171331769(-) A-I      intronic chr5:171331795(-) A-I      intronic chr5:171373994(-) A-I      intronic chr5:171317405(-) A-I      intronic chr5:171373992(-) A-I      intronic chr5:171364710(-) A-I      intronic chr5:171365267(-) A-I      intronic chr5:171386634(-) A-I      intronic chr5:171380199(-) A-I      intronic chr5:171378662(-) A-I      intronic chr5:171378663(-) A-I      intronic chr5:171414658(-) A-I      intronic chr5:171361493(-) A-I      intronic chr5:171378355(-) A-I      intronic chr5:171425397(-) A-I      intronic chr5:171398730(-) A-I      intronic chr5:171331687(-) A-I      intronic chr5:171369599(-) A-I      intronic chr5:171417859(-) A-I      intronic chr5:171396872(-) A-I      intronic chr5:171396846(-) A-I      intronic chr5:171413336(-) A-I      intronic chr5:171418971(-) A-I      intronic chr5:171365182(-) A-I      intronic chr5:171378664(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FBXW11	chr5:171314800(-) A-G intron -    22484847 chr5:171314856(-) A-G intron -    22484847 chr5:171314919(-) A-G intron -    22484847 chr5:171330302(-) A-G intron -    22484847 chr5:171331050(-) A-G intron -    22484847 chr5:171331189(-) A-G intron -    22484847 chr5:171331202(-) G-C intron -    22484847 chr5:171331223(-) A-G intron -    22484847 chr5:171331687(-) A-G intron -    22484847 chr5:171331704(-) A-G intron -    22484847 chr5:171331714(-) A-G intron -    22484847 chr5:171331769(-) A-G intron -    22484847 chr5:171331795(-) A-G intron -    22484847 chr5:171331841(-) A-G intron -    22484847 chr5:171331846(-) A-G intron -    22484847 chr5:171348939(-) A-G intron -    22484847 chr5:171351022(-) A-G intron -    22484847 chr5:171358981(-) A-G intron -    22484847 chr5:171359074(-) A-G intron -    22484847 chr5:171361598(-) A-G intron -    22484847 chr5:171362061(-) A-G intron -    22484847 chr5:171362096(-) A-G intron -    22484847 chr5:171364583(-) A-G intron -    22484847 chr5:171364710(-) A-G intron -    22484847 chr5:171364749(-) A-G intron -    22484847 chr5:171364796(-) A-G intron -    22484847 chr5:171365267(-) A-G intron -    22484847 chr5:171365340(-) A-G intron -    22484847 chr5:171365362(-) A-G intron -    22484847 chr5:171369599(-) A-G intron -    22484847 chr5:171369770(-) A-G intron -    22484847 chr5:171370600(-) A-G intron -    22484847 chr5:171373956(-) A-G intron -    22484847 chr5:171374001(-) A-G intron -    22484847 chr5:171374064(-) A-G intron -    22484847 chr5:171374113(-) A-G intron -    22484847 chr5:171374861(-) A-G intron -    22484847 chr5:171374864(-) A-G intron -    22484847 chr5:171378322(-) A-G intron -    22484847 chr5:171378336(-) A-G intron -    22484847 chr5:171378368(-) A-G intron -    22484847 chr5:171378497(-) A-G intron -    22484847 chr5:171378508(-) A-G intron -    22484847 chr5:171378659(-) A-G intron -    22484847 chr5:171378662(-) A-G intron -    22484847 chr5:171378664(-) A-G intron -    22484847 chr5:171378665(-) A-G intron -    22484847 chr5:171378770(-) A-G intron -    22484847 chr5:171395271(-) A-G intron -    22484847 chr5:171396150(-) A-G intron -    22484847 chr5:171396220(-) A-G intron -    22484847 chr5:171396845(-) A-G intron -    22484847 chr5:171396872(-) A-G intron -    22484847 chr5:171396908(-) A-G intron -    22484847 chr5:171396951(-) A-G intron -    22484847 chr5:171396972(-) C-T intron -    22484847 chr5:171398730(-) A-G intron -    22484847 chr5:171398742(-) A-G intron -    22484847 chr5:171398769(-) A-G intron -    22484847 chr5:171398794(-) A-G intron -    22484847 chr5:171398814(-) A-G intron -    22484847 chr5:171398815(-) A-G intron -    22484847 chr5:171399001(-) A-G intron -    22484847 chr5:171399023(-) G-A intron -    22484847 chr5:171399064(-) A-G intron -    22484847 chr5:171399149(-) A-G intron -    22484847 chr5:171399247(-) A-G intron -    22484847 chr5:171399264(-) A-G intron -    22484847 chr5:171399686(-) A-G intron -    22484847 chr5:171399743(-) A-G intron -    22484847 chr5:171399786(-) A-G intron -    22484847 chr5:171399822(-) A-G intron -    22484847 chr5:171401236(-) A-G intron -    22484847 chr5:171401247(-) A-G intron -    22484847 chr5:171401611(-) A-G intron -    22484847 chr5:171401997(-) A-G intron -    22484847 chr5:171402025(-) A-G intron -    22484847 chr5:171404039(-) G-T intron -    22484847 chr5:171409471(-) A-G intron -    22484847 chr5:171409526(-) A-G intron -    22484847 chr5:171410112(-) A-G intron -    22484847 chr5:171410188(-) A-G intron -    22484847 chr5:171413268(-) G-A intron -    22484847 chr5:171413336(-) A-G intron -    22484847 chr5:171413456(-) A-G intron -    22484847 chr5:171413742(-) T-C intron -    22484847 chr5:171414593(-) A-G intron -    22484847 chr5:171414594(-) A-G intron -    22484847 chr5:171414607(-) A-G intron -    22484847 chr5:171414658(-) A-G intron -    22484847 chr5:171414694(-) A-G intron -    22484847 chr5:171414743(-) A-G intron -    22484847 chr5:171415787(-) A-G intron -    22484847 chr5:171416059(-) A-G intron -    22484847 chr5:171416167(-) A-G intron -    22484847 chr5:171417941(-) A-G intron -    22484847 chr5:171417967(-) A-G intron -    22484847 chr5:171417968(-) A-G intron -    22484847 chr5:171417990(-) A-G intron -    22484847 chr5:171417994(-) A-G intron -    22484847 chr5:171418023(-) A-G intron -    22484847 chr5:171418049(-) A-G intron -    22484847 chr5:171418076(-) A-G intron -    22484847 chr5:171418097(-) A-G intron -    22484847 chr5:171418102(-) A-G intron -    22484847 chr5:171418971(-) A-G intron -    22484847 chr5:171419124(-) C-T intron -    22484847 chr5:171419132(-) C-T intron -    22484847 chr5:171419331(-) A-G intron -    22484847 chr5:171419369(-) A-G intron -    22484847 chr5:171421898(-) A-G intron -    22484847 chr5:171423545(-) A-G intron -    22484847 chr5:171425633(-) A-G intron -    22484847 chr5:171425800(-) G-T intron -    22484847 chr5:171429911(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FBXW11	chr5:171288946-171288947(-) Y 3'UTR       26075521 chr5:171288981-171288982(-) m6A 3'UTR       - chr5:171289019-171289020(-) m6A 3'UTR       - chr5:171290737-171290738(-) m6A 3'UTR       24981863 chr5:171290786-171290787(-) m6A 3'UTR       24981863 chr5:171290903-171290904(-) m6A 3'UTR       24284625 chr5:171290930-171290931(-) m6A 3'UTR       24284625 chr5:171294874-171294875(-) m6A exon//intron       27773535 chr5:171294929-171294930(-) m6A exon//intron       27773535 chr5:171294944-171294945(-) m6A exon//intron       27773535 chr5:171337595-171337596(-) m6A 3'UTR//CDS       27773535//22608085 chr5:171337633-171337634(-) m6A 3'UTR//CDS       24981863//27773535//22608085 chr5:171337669-171337670(-) m6A 3'UTR//CDS       24981863//27773535//22608085 chr5:171337727-171337728(-) m6A 3'UTR//CDS       24981863//27773535//22608085 chr5:171337745-171337746(-) m6A 3'UTR//CDS//exon       24981863//22608085 chr5:171337788-171337789(-) m6A 3'UTR//CDS//exon       24981863//22608085 chr5:171433475-171433476(-) m6A CDS//exon       27371828//27773536 chr5:171433480-171433481(-) m6A CDS//exon       27371828//27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3682-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	FBXW11	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3682-3p
Interactor2: FBXW11

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.