Basic Information:

  VIRBase ID:  

HHID00073878

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3662:  MIMAT0018083          FAM91A1:  NM_001317917     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3662	FAM91A1
miRBase Accession/Entrez ID	MIMAT0018083	157769
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3662	rs1269591251 chr6:134979367    C/T rs1392974872 chr6:134979361    T/C rs779534942 chr6:134979360    G/A rs748588809 chr6:134979372    C/A rs748588809 chr6:134979372    C/T rs763349803 chr6:134979371    TC/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FAM91A1	chr8:124788229(+) A-I      intronic chr8:124787973(+) A-I      intronic chr8:124788098(+) A-I      intronic chr8:124809149(+) A-I      intronic chr8:124815276(+) A-I      intronic chr8:124816497(+) A-I      intronic chr8:124816611(+) A-I      intronic chr8:124809216(+) A-I      intronic chr8:124809048(+) A-I      intronic chr8:124809049(+) A-I      intronic chr8:124809174(+) A-I      intronic chr8:124795391(+) A-I      intronic chr8:124809180(+) A-I      intronic chr8:124809189(+) A-I      intronic chr8:124795148(+) A-I      intronic chr8:124809213(+) A-I      intronic chr8:124809207(+) A-I      intronic chr8:124815693(+) A-I      intronic chr8:124809233(+) A-I      intronic chr8:124824241(+) A-I      intronic chr8:124816524(+) A-I      intronic chr8:124808844(+) A-I      intronic chr8:124795323(+) A-I      intronic chr8:124793939(+) A-I      intronic chr8:124815349(+) A-I      intronic chr8:124793934(+) A-I      intronic chr8:124795336(+) A-I      intronic chr8:124816525(+) A-I      intronic chr8:124816610(+) A-I      intronic chr8:124815362(+) A-I      intronic chr8:124793999(+) A-I      intronic chr8:124815343(+) A-I      intronic chr8:124815298(+) A-I      intronic chr8:124808761(+) A-I      intronic chr8:124815651(+) A-I      intronic chr8:124808764(+) A-I      intronic chr8:124815680(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FAM91A1	chr8:124782226(+) C-T intron -    22484847 chr8:124793999(+) A-G intron -    22484847 chr8:124795336(+) A-G intron -    22484847 chr8:124804203(+) T-C intron -    22484847 chr8:124808761(+) A-G intron -    22484847 chr8:124808764(+) A-G intron -    22484847 chr8:124809233(+) A-G intron -    22484847 chr8:124815349(+) A-G intron -    22484847 chr8:124815651(+) A-G intron -    22484847 chr8:124815680(+) A-G intron -    22484847 chr8:124815693(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FAM91A1	chr8:124780701-124780702(+) m6A 5'UTR       24981863 chr8:124780712-124780713(+) m6A 5'UTR       24981863 chr8:124780785-124780786(+) m6A 5'UTR       24981863 chr8:124811798-124811799(+) Y 3'UTR//CDS       26075521 chr8:124818370-124818371(+) m6A 3'UTR//CDS       - chr8:124818379-124818380(+) m6A 3'UTR//CDS       - chr8:124818443-124818444(+) m6A 3'UTR//CDS       - chr8:124820515-124820516(+) m6A 3'UTR//CDS       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3662	Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     - Mitochondrion Cell line (HEK-293|HeLa)     22984580
	FAM91A1	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3662
Interactor2: FAM91A1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.