Detail Information

Basic Information:


  VIRBase ID:  

HHID00073877

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3662:           TMEM161B:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3662 TMEM161B
miRBase
Accession/Entrez ID		 MIMAT0018083 153396
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - FLB3342//PRO1313

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3662
rs1269591251 chr6:134979367    C/T
rs1392974872 chr6:134979361    T/C
rs779534942 chr6:134979360    G/A
rs748588809 chr6:134979372    C/A
rs748588809 chr6:134979372    C/T
rs763349803 chr6:134979371    TC/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TMEM161B
chr5:87525678(-) A-I      intronic
chr5:87525658(-) A-I      intronic
chr5:87517234(-) A-I      intronic
chr5:87507510(-) A-I      intronic
chr5:87517264(-) A-I      intronic
chr5:87517954(-) A-I      intronic
chr5:87525740(-) A-I      intronic
chr5:87530671(-) A-I      intronic
chr5:87517153(-) A-I      intronic
chr5:87517240(-) A-I      intronic
chr5:87518024(-) A-I      intronic
chr5:87528664(-) A-I      intronic
chr5:87522897(-) A-I      intronic
chr5:87517181(-) A-I      intronic
chr5:87525684(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TMEM161B
chr5:87517240(-) A-G intron -    22484847
chr5:87517264(-) A-G intron -    22484847
chr5:87525684(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TMEM161B
chr5:87485541-87485542(-) m6A 3'UTR       27773535
chr5:87491557-87491558(-) Y 3'UTR//intron       26075521
chr5:87491917-87491918(-) m6A 3'UTR//intron       24981863//27773535//22608085
chr5:87491951-87491952(-) m6A 3'UTR//intron       24981863//27773535//22608085
chr5:87492079-87492080(-) Y 3'UTR//CDS//intron       26075521
chr5:87492120-87492121(-) m6A 3'UTR//CDS//intron       24284625//24981863//27773535//22608085
chr5:87564589-87564590(-) m6A 5'UTR//exon//intron       24981863
chr5:87564611-87564612(-) m6A 5'UTR//exon       24981863
chr5:87564650-87564651(-) m6A 5'UTR//exon       24981863
chr5:87564693-87564694(-) m6A exon       25456834//24981863
chr5:87565183-87565184(-) m6A exon       24284625//24981863//22608085
chr5:87565200-87565201(-) m6A exon       24284625//24981863//22608085
chr5:87565266-87565267(-) m6A exon       24284625

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3662
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
TMEM161B
Chromatin K562 cells     -
Cytosol K562 cells     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3662
Interactor2: TMEM161B

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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