Basic Information:

  VIRBase ID:  

HHID00073869

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3662:  MIMAT0018083          FAM199X:  NM_207318     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3662	FAM199X
miRBase Accession/Entrez ID	MIMAT0018083	139231
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CXorf39

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3662	rs1269591251 chr6:134979367    C/T rs1392974872 chr6:134979361    T/C rs779534942 chr6:134979360    G/A rs748588809 chr6:134979372    C/A rs748588809 chr6:134979372    C/T rs763349803 chr6:134979371    TC/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FAM199X	chrX:103414483(+) A-I      intronic chrX:103414464(+) A-I      intronic chrX:103417716(+) A-I      intronic chrX:103414446(+) A-I      intronic chrX:103414438(+) A-I      intronic chrX:103418785(+) A-I      intronic chrX:103418700(+) A-I      intronic chrX:103422980(+) A-I      intronic chrX:103423571(+) A-I      intronic chrX:103417675(+) A-I      intronic chrX:103417707(+) A-I      intronic chrX:103416902(+) A-I      intronic chrX:103416996(+) A-I      intronic chrX:103417735(+) A-I      intronic chrX:103417700(+) A-I      intronic chrX:103423750(+) A-I      intronic chrX:103417857(+) A-I      intronic chrX:103417002(+) A-I      intronic chrX:103418862(+) A-I      intronic chrX:103414423(+) A-I      intronic chrX:103418770(+) A-I      intronic chrX:103422917(+) A-I      intronic chrX:103414329(+) A-I      intronic chrX:103414274(+) A-I      intronic chrX:103418777(+) A-I      intronic chrX:103423610(+) A-I      intronic chrX:103414421(+) A-I      intronic chrX:103423045(+) A-I      intronic chrX:103423752(+) A-I      intronic chrX:103414429(+) A-I      intronic chrX:103414388(+) A-I      intronic chrX:103422922(+) A-I      intronic chrX:103422977(+) A-I      intronic chrX:103423609(+) A-I      intronic chrX:103423087(+) A-I      intronic chrX:103417676(+) A-I      intronic chrX:103414297(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FAM199X	chrX:103435264(+) T-G intron -    21725310 chrX:103417676(+) A-G intron -    22484847 chrX:103417700(+) A-G intron -    22484847 chrX:103418770(+) A-G intron -    22484847 chrX:103418777(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FAM199X	chrX:103411386-103411387(+) m6A 5'UTR       - chrX:103432895-103432896(+) m6A CDS//intron       22575960 chrX:103432907-103432908(+) m6A CDS//intron       22575960 chrX:103434427-103434428(+) m6A CDS//exon       24284625//25456834//24981863//22608085 chrX:103435673-103435674(+) m6A 3'UTR//exon       - chrX:103435701-103435702(+) m6A 3'UTR//exon       - chrX:103435818-103435819(+) m6A 3'UTR//exon       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3662	Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     - Mitochondrion Cell line (HEK-293|HeLa)     22984580
	FAM199X	Chromatin K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3662
Interactor2: FAM199X

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.