Detail Information

Basic Information:


  VIRBase ID:  

HHID00073863

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3662:           CD200R1:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3662 CD200R1
miRBase
Accession/Entrez ID		 MIMAT0018083 131450
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CD200R//HCRTR2//MOX2R//OX2R

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3662
rs1269591251 chr6:134979367    C/T
rs1392974872 chr6:134979361    T/C
rs779534942 chr6:134979360    G/A
rs748588809 chr6:134979372    C/A
rs748588809 chr6:134979372    C/T
rs763349803 chr6:134979371    TC/T

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CD200R1
chr3:112642399-112642400(-) m6A 3'UTR       -
chr3:112642437-112642438(-) m6A 3'UTR       -
chr3:112642498-112642499(-) m6A 3'UTR       -
chr3:112642514-112642515(-) m6A 3'UTR       -
chr3:112642539-112642540(-) m6A 3'UTR//CDS       -
chr3:112642584-112642585(-) m6A 3'UTR//CDS       -
chr3:112642608-112642609(-) m6A 3'UTR//CDS       -
chr3:112693709-112693710(-) m6A 5'UTR       -
chr3:112693877-112693878(-) m6A 5'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3662
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
CD200R1
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3662
Interactor2: CD200R1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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