Basic Information:

  VIRBase ID:  

HHID00073853

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3662:  MIMAT0018083          UBE2Q2:  NM_001145335     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3662	UBE2Q2
miRBase Accession/Entrez ID	MIMAT0018083	92912
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3662	rs1269591251 chr6:134979367    C/T rs1392974872 chr6:134979361    T/C rs779534942 chr6:134979360    G/A rs748588809 chr6:134979372    C/A rs748588809 chr6:134979372    C/T rs763349803 chr6:134979371    TC/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	UBE2Q2	chr15:76177656(+) A-I      intronic chr15:76138812(+) A-I      intronic chr15:76185878(+) A-I      intronic chr15:76168356(+) A-I      intronic chr15:76166754(+) A-I      intronic chr15:76138682(+) A-I      intronic chr15:76166140(+) A-I      intronic chr15:76177565(+) A-I      intronic chr15:76158755(+) A-I      intronic chr15:76158730(+) A-I      intronic chr15:76177561(+) A-I      intronic chr15:76158703(+) A-I      intronic chr15:76170908(+) A-I      intronic chr15:76162483(+) A-I      intronic chr15:76162489(+) A-I      intronic chr15:76162508(+) A-I      intronic chr15:76162512(+) A-I      intronic chr15:76164510(+) A-I      intronic chr15:76172620(+) A-I      intronic chr15:76172628(+) A-I      intronic chr15:76173039(+) A-I      intronic chr15:76178626(+) A-I      intronic chr15:76170923(+) A-I      intronic chr15:76178641(+) A-I      intronic chr15:76172637(+) A-I      intronic chr15:76178644(+) A-I      intronic chr15:76178670(+) A-I      intronic chr15:76179063(+) A-I      intronic chr15:76179070(+) A-I      intronic chr15:76179077(+) A-I      intronic chr15:76166805(+) A-I      intronic chr15:76191345(+) A-I      intronic chr15:76178627(+) A-I      intronic chr15:76170903(+) A-I      intronic chr15:76179134(+) A-I      intronic chr15:76179140(+) A-I      intronic chr15:76179153(+) A-I      intronic chr15:76186637(+) A-I      intronic chr15:76187273(+) A-I      intronic chr15:76166808(+) A-I      intronic chr15:76166814(+) A-I      intronic chr15:76166825(+) A-I      intronic chr15:76166901(+) A-I      intronic chr15:76168192(+) A-I      intronic chr15:76169427(+) A-I      intronic chr15:76170793(+) A-I      intronic chr15:76187278(+) A-I      intronic chr15:76187319(+) A-I      intronic chr15:76170901(+) A-I      intronic chr15:76187380(+) A-I      intronic chr15:76187430(+) A-I      intronic chr15:76187626(+) A-I      intronic chr15:76187655(+) A-I      intronic chr15:76170895(+) A-I      intronic chr15:76191346(+) A-I      intronic chr15:76191494(+) A-I      intronic chr15:76191497(+) A-I      intronic chr15:76191502(+) A-I      intronic chr15:76191523(+) A-I      intronic chr15:76172619(+) A-I      intronic chr15:76170872(+) A-I      intronic chr15:76169417(+) A-I      intronic chr15:76179050(+) A-I      intronic chr15:76178658(+) A-I      intronic chr15:76189747(+) A-I      intronic chr15:76187439(+) A-I      intronic chr15:76172971(+) A-I      intronic chr15:76179125(+) A-I      intronic chr15:76178650(+) A-I      intronic chr15:76164514(+) A-I      intronic chr15:76145635(+) A-I      intronic chr15:76189834(+) A-I      intronic chr15:76166082(+) A-I      intronic chr15:76189767(+) A-I      intronic chr15:76179081(+) A-I      intronic chr15:76168254(+) A-I      intronic chr15:76186811(+) A-I      intronic chr15:76168296(+) A-I      intronic chr15:76187660(+) A-I      intronic chr15:76189745(+) A-I      intronic chr15:76189821(+) A-I      intronic chr15:76145718(+) A-I      intronic chr15:76169289(+) A-I      intronic chr15:76187447(+) A-I      intronic chr15:76179049(+) A-I      intronic chr15:76155045(+) A-I      intronic chr15:76187652(+) A-I      intronic chr15:76186651(+) A-I      intronic chr15:76172923(+) A-I      intronic chr15:76169236(+) A-I      intronic chr15:76170785(+) A-I      intronic chr15:76178590(+) A-I      intronic chr15:76166202(+) A-I      intronic chr15:76187581(+) A-I      intronic chr15:76173051(+) A-I      intronic chr15:76166218(+) A-I      intronic chr15:76178484(+) A-I      intronic chr15:76173022(+) A-I      intronic chr15:76191351(+) A-I      intronic chr15:76187607(+) A-I      intronic chr15:76191496(+) A-I      intronic chr15:76187606(+) A-I      intronic chr15:76184945(+) A-I      intronic chr15:76178979(+) A-I      intronic chr15:76178480(+) A-I      intronic chr15:76166899(+) A-I      intronic chr15:76169288(+) A-I      intronic chr15:76149174(+) A-I      intronic chr15:76179076(+) A-I      intronic chr15:76155058(+) A-I      intronic chr15:76177639(+) A-I      intronic chr15:76166711(+) A-I      intronic chr15:76178982(+) A-I      intronic chr15:76178560(+) A-I      intronic chr15:76168352(+) A-I      intronic chr15:76189842(+) A-I      intronic chr15:76186681(+) A-I      intronic chr15:76189836(+) A-I      intronic chr15:76177541(+) A-I      intronic chr15:76170789(+) A-I      intronic chr15:76187479(+) A-I      intronic chr15:76169354(+) A-I      intronic chr15:76184952(+) A-I      intronic chr15:76145652(+) A-I      intronic chr15:76173042(+) A-I      intronic chr15:76158562(+) A-I      intronic chr15:76186804(+) A-I      intronic chr15:76168255(+) A-I      intronic chr15:76169283(+) A-I      intronic chr15:76184946(+) A-I      intronic chr15:76187406(+) A-I      intronic chr15:76187789(+) A-I      intronic chr15:76155062(+) A-I      intronic chr15:76145610(+) A-I      intronic chr15:76191412(+) A-I      intronic chr15:76179149(+) A-I      intronic chr15:76177563(+) A-I      intronic chr15:76144353(+) A-I      intronic chr15:76144415(+) A-I      intronic chr15:76169240(+) A-I      intronic chr15:76145557(+) A-I      intronic chr15:76169265(+) A-I      intronic chr15:76187776(+) A-I      intronic chr15:76168256(+) A-I      intronic chr15:76187281(+) A-I      intronic chr15:76145737(+) A-I      intronic chr15:76187630(+) A-I      intronic chr15:76179108(+) A-I      intronic chr15:76191513(+) A-I      intronic chr15:76178974(+) A-I      intronic chr15:76166130(+) A-I      intronic chr15:76166141(+) A-I      intronic chr15:76168148(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	UBE2Q2	chr15:76166082(+) A-I intron -    22327324 chr15:76177024(+) A-I intron -    21960545 chr15:76166082(+) A-G intron -    22484847 chr15:76179049(+) A-G intron -    22484847 chr15:76179081(+) A-G intron -    22484847 chr15:76187652(+) A-G intron -    22484847 chr15:76187660(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	UBE2Q2	chr15:76136065-76136066(+) m6A CDS       - chr15:76152250-76152251(+) m6A CDS//intron       27773535 chr15:76161297-76161298(+) m6A CDS//intron       24981863//27773535//22608085 chr15:76165778-76165779(+) m6A CDS//intron       24981863//27773535//22608085 chr15:76165885-76165886(+) m6A CDS//intron       24981863//27773535 chr15:76165898-76165899(+) m6A CDS//intron       24981863//27773535 chr15:76168562-76168563(+) m6A CDS//intron       24981863//27773535 chr15:76168582-76168583(+) m6A CDS//intron       24981863//27773535 chr15:76168589-76168590(+) Cm CDS//intron       - chr15:76168608-76168609(+) m6A CDS//intron       24981863 chr15:76170317-76170318(+) m6A CDS//intron       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3662	Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     - Mitochondrion Cell line (HEK-293|HeLa)     22984580
	UBE2Q2	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3662
Interactor2: UBE2Q2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.