Detail Information

Basic Information:


  VIRBase ID:  

HHID00073804

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3662:           KLHL11:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3662 KLHL11
miRBase
Accession/Entrez ID		 MIMAT0018083 55175
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3662
rs1269591251 chr6:134979367    C/T
rs1392974872 chr6:134979361    T/C
rs779534942 chr6:134979360    G/A
rs748588809 chr6:134979372    C/A
rs748588809 chr6:134979372    C/T
rs763349803 chr6:134979371    TC/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR KLHL11
chr17:40008517(-) A-I      3'UTR
chr17:40008482(-) A-I      3'UTR
chr17:40008474(-) A-I      3'UTR
chr17:40008447(-) A-I      3'UTR
chr17:40007612(-) A-I      3'UTR
chr17:40007602(-) A-I      3'UTR
chr17:40008911(-) A-I      3'UTR
chr17:40008921(-) A-I      3'UTR
chr17:40012207(-) A-I      intronic
chr17:40015915(-) A-I      intronic
chr17:40008369(-) A-I      3'UTR
chr17:40008141(-) A-I      3'UTR
chr17:40008533(-) A-I      3'UTR
chr17:40008488(-) A-I      3'UTR
chr17:40007802(-) A-I      3'UTR
chr17:40008472(-) A-I      3'UTR
chr17:40008470(-) A-I      3'UTR
chr17:40008547(-) A-I      3'UTR
chr17:40007621(-) A-I      3'UTR
chr17:40008448(-) A-I      3'UTR
chr17:40008343(-) A-I      3'UTR
chr17:40007754(-) A-I      3'UTR
chr17:40008383(-) A-I      3'UTR
chr17:40008306(-) A-I      3'UTR
chr17:40007674(-) A-I      3'UTR
chr17:40007791(-) A-I      3'UTR
chr17:40008462(-) A-I      3'UTR
chr17:40008393(-) A-I      3'UTR
chr17:40008035(-) A-I      3'UTR
chr17:40007650(-) A-I      3'UTR
chr17:40018403(-) A-I      intronic
chr17:40019556(-) A-I      intronic
chr17:40019613(-) A-I      intronic
chr17:40008433(-) A-I      3'UTR
chr17:40013220(-) A-I      intronic
chr17:40008894(-) A-I      3'UTR
chr17:40019628(-) A-I      intronic
chr17:40007848(-) A-I      3'UTR
chr17:40008436(-) A-I      3'UTR
chr17:40008877(-) A-I      3'UTR
chr17:40008487(-) A-I      3'UTR
chr17:40007583(-) A-I      3'UTR
chr17:40017772(-) A-I      intronic
chr17:40008895(-) A-I      3'UTR
chr17:40008116(-) A-I      3'UTR
chr17:40007849(-) A-I      3'UTR
chr17:40007722(-) A-I      3'UTR
chr17:40012667(-) A-I      intronic
chr17:40007590(-) A-I      3'UTR
chr17:40008439(-) A-I      3'UTR
chr17:40008786(-) A-I      3'UTR
chr17:40008495(-) A-I      3'UTR
chr17:40008451(-) A-I      3'UTR
chr17:40008041(-) A-I      3'UTR
chr17:40008341(-) A-I      3'UTR
chr17:40007444(-) A-I      3'UTR
chr17:40017829(-) A-I      intronic
chr17:40008464(-) A-I      3'UTR
chr17:40008863(-) A-I      3'UTR
chr17:40008428(-) A-I      3'UTR
chr17:40008100(-) A-I      3'UTR
chr17:40008860(-) A-I      3'UTR
chr17:40008403(-) A-I      3'UTR
chr17:40007599(-) A-I      3'UTR
chr17:40008560(-) A-I      3'UTR
chr17:40008960(-) A-I      3'UTR
chr17:40007990(-) A-I      3'UTR
chr17:40007671(-) A-I      3'UTR
chr17:40008880(-) A-I      3'UTR
chr17:40017821(-) A-I      intronic
chr17:40007706(-) A-I      3'UTR
chr17:40008536(-) A-I      3'UTR
chr17:40008542(-) A-I      3'UTR
chr17:40008541(-) A-I      3'UTR
chr17:40008437(-) A-I      3'UTR
chr17:40008808(-) A-I      3'UTR
chr17:40007649(-) A-I      3'UTR
chr17:40008438(-) A-I      3'UTR
chr17:40008420(-) A-I      3'UTR
chr17:40008446(-) A-I      3'UTR
chr17:40014913(-) A-I      intronic
chr17:40018438(-) A-I      intronic
chr17:40018437(-) A-I      intronic
chr17:40014334(-) A-I      intronic
chr17:40017891(-) A-I      intronic
chr17:40017816(-) A-I      intronic
chr17:40014016(-) A-I      intronic
chr17:40007907(-) A-I      3'UTR
chr17:40008382(-) A-I      3'UTR
chr17:40008449(-) A-I      3'UTR
chr17:40007611(-) A-I      3'UTR
chr17:40008465(-) A-I      3'UTR
chr17:40008509(-) A-I      3'UTR
chr17:40008051(-) A-I      3'UTR
chr17:40007966(-) A-I      3'UTR
chr17:40008943(-) A-I      3'UTR
chr17:40008980(-) A-I      3'UTR
chr17:40007975(-) A-I      3'UTR
chr17:40008468(-) A-I      3'UTR
chr17:40008413(-) A-I      3'UTR
chr17:40008931(-) A-I      3'UTR
chr17:40008063(-) A-I      3'UTR
chr17:40007850(-) A-I      3'UTR
chr17:40005424(-) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase KLHL11
chr17:40009832-40009833(-) m6A 3'UTR       24981863//27773535//22575960//22608085
chr17:40009847-40009848(-) m6A 3'UTR       24981863//27773535//22575960//22608085
chr17:40009885-40009886(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085
chr17:40009966-40009967(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr17:40010028-40010029(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr17:40010060-40010061(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr17:40010070-40010071(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr17:40010088-40010089(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr17:40010243-40010244(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr17:40010262-40010263(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr17:40010437-40010438(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr17:40010448-40010449(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr17:40010527-40010528(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr17:40010574-40010575(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr17:40010580-40010581(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr17:40010616-40010617(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr17:40010738-40010739(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr17:40010777-40010778(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr17:40010816-40010817(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr17:40010854-40010855(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr17:40010921-40010922(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr17:40010964-40010965(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr17:40011003-40011004(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr17:40011048-40011049(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr17:40011134-40011135(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr17:40011197-40011198(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr17:40011224-40011225(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr17:40011257-40011258(-) m6A CDS       24284625//24981863//27773535//22608085
chr17:40011313-40011314(-) m6A CDS       24284625//24981863//27773535//22608085
chr17:40011366-40011367(-) m6A CDS       24284625//24981863//22608085
chr17:40021173-40021174(-) m6A CDS       27773536
chr17:40021483-40021484(-) m6A CDS       24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr17:40021518-40021519(-) m6A CDS       24209618//25456834//24981863//27371828//27773536//22575960//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3662
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
KLHL11
Exosome Blood     -
Nucleolus K562 cells     -
Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3662
Interactor2: KLHL11

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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