Basic Information:

  VIRBase ID:  

HHID00073582

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3662:  MIMAT0018083          AHR:  NM_001621     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3662	AHR
miRBase Accession/Entrez ID	MIMAT0018083	196
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	bHLHe76//RP85

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3662	rs1269591251 chr6:134979367    C/T rs1392974872 chr6:134979361    T/C rs779534942 chr6:134979360    G/A rs748588809 chr6:134979372    C/A rs748588809 chr6:134979372    C/T rs763349803 chr6:134979371    TC/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	AHR	chr7:17384944(+) A-I      3'UTR chr7:17384943(+) A-I      3'UTR chr7:17384942(+) A-I      3'UTR chr7:17384897(+) A-I      3'UTR chr7:17384859(+) A-I      3'UTR chr7:17384841(+) A-I      3'UTR chr7:17384500(+) A-I      3'UTR chr7:17384835(+) A-I      3'UTR chr7:17384824(+) A-I      3'UTR chr7:17384789(+) A-I      3'UTR chr7:17384788(+) A-I      3'UTR chr7:17384762(+) A-I      3'UTR chr7:17384755(+) A-I      3'UTR chr7:17384749(+) A-I      3'UTR chr7:17384732(+) A-I      3'UTR chr7:17384729(+) A-I      3'UTR chr7:17384702(+) A-I      3'UTR chr7:17384524(+) A-I      3'UTR chr7:17384513(+) A-I      3'UTR chr7:17384473(+) A-I      3'UTR chr7:17384450(+) A-I      3'UTR chr7:17384415(+) A-I      3'UTR chr7:17384406(+) A-I      3'UTR chr7:17384399(+) A-I      3'UTR chr7:17384333(+) A-I      3'UTR chr7:17384317(+) A-I      3'UTR chr7:17384315(+) A-I      3'UTR chr7:17384304(+) A-I      3'UTR chr7:17384299(+) A-I      3'UTR chr7:17384285(+) A-I      3'UTR chr7:17384279(+) A-I      3'UTR chr7:17384277(+) A-I      3'UTR chr7:17384275(+) A-I      3'UTR chr7:17384273(+) A-I      3'UTR chr7:17384915(+) A-I      3'UTR chr7:17384902(+) A-I      3'UTR chr7:17384850(+) A-I      3'UTR chr7:17384409(+) A-I      3'UTR chr7:17384441(+) A-I      3'UTR chr7:17384354(+) A-I      3'UTR chr7:17384777(+) A-I      3'UTR chr7:17384818(+) A-I      3'UTR chr7:17384886(+) A-I      3'UTR chr7:17384926(+) A-I      3'UTR chr7:17384420(+) A-I      3'UTR chr7:17384437(+) A-I      3'UTR chr7:17384778(+) A-I      3'UTR chr7:17384774(+) A-I      3'UTR chr7:17384474(+) A-I      3'UTR chr7:17384724(+) A-I      3'UTR chr7:17384677(+) A-I      3'UTR chr7:17384880(+) A-I      3'UTR chr7:17384941(+) A-I      3'UTR chr7:17384811(+) A-I      3'UTR chr7:17384853(+) A-I      3'UTR chr7:17384889(+) A-I      3'UTR chr7:17384462(+) A-I      3'UTR chr7:17384529(+) A-I      3'UTR chr7:17384792(+) A-I      3'UTR chr7:17384393(+) A-I      3'UTR chr7:17384527(+) A-I      3'UTR chr7:17384851(+) A-I      3'UTR chr7:17384845(+) A-I      3'UTR chr7:17384940(+) A-I      3'UTR chr7:17384781(+) A-I      3'UTR chr7:17384371(+) A-I      3'UTR chr7:17384395(+) A-I      3'UTR chr7:17384740(+) A-I      3'UTR chr7:17384380(+) A-I      3'UTR chr7:17384515(+) A-I      3'UTR chr7:17384334(+) A-I      3'UTR chr7:17384685(+) A-I      3'UTR chr7:17384358(+) A-I      3'UTR chr7:17384882(+) A-I      3'UTR chr7:17384694(+) A-I      3'UTR chr7:17384440(+) A-I      3'UTR chr7:17384298(+) A-I      3'UTR chr7:17384482(+) A-I      3'UTR chr7:17384780(+) A-I      3'UTR chr7:17384730(+) A-I      3'UTR chr7:17384738(+) A-I      3'UTR chr7:17384434(+) A-I      3'UTR

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	AHR	chr7:17384298(+) A-I exon 3'UTR    15342557 chr7:17384318(+) A-I exon 3'UTR    15342557 chr7:17384334(+) A-I exon 3'UTR    15342557 chr7:17384353(+) A-I exon 3'UTR    15342557   //21960545   //22327324 chr7:17384354(+) A-I exon 3'UTR    15342557   //22327324 chr7:17384358(+) A-I exon 3'UTR    15342557   //15258596 chr7:17384371(+) A-I exon 3'UTR    15342557 chr7:17384380(+) A-I exon 3'UTR    15342557 chr7:17384393(+) A-I exon 3'UTR    15258596 chr7:17384395(+) A-I exon 3'UTR    15258596   //21960545 chr7:17384434(+) A-I exon 3'UTR    15342557 chr7:17384437(+) A-I exon 3'UTR    15342557 chr7:17384440(+) A-I exon 3'UTR    15342557 chr7:17384462(+) A-I exon 3'UTR    15342557 chr7:17384482(+) A-I exon 3'UTR    15342557 chr7:17384514(+) A-I exon 3'UTR    15342557   //22327324 chr7:17384515(+) A-I exon 3'UTR    15342557 chr7:17384527(+) A-I exon 3'UTR    15342557 chr7:17384669(+) A-I exon 3'UTR    15342557 chr7:17384730(+) A-I exon 3'UTR    15342557   //22028664   //22327324 chr7:17384763(+) A-I exon 3'UTR    15342557 chr7:17384774(+) A-I exon 3'UTR    15342557   //22028664   //22327324 chr7:17384777(+) A-I exon 3'UTR    15342557   //22028664   //22327324 chr7:17384778(+) A-I exon 3'UTR    15342557   //22028664   //22327324 chr7:17384779(+) A-I exon 3'UTR    15342557   //22327324 chr7:17384780(+) A-I exon 3'UTR    15342557 chr7:17384783(+) A-I exon 3'UTR    15342557   //22028664 chr7:17384785(+) A-I exon 3'UTR    15342557 chr7:17384792(+) A-I exon 3'UTR    15342557   //22028664   //22327324 chr7:17384818(+) A-I exon 3'UTR    15342557   //22028664   //21960545   //22327324 chr7:17384832(+) A-I exon 3'UTR    15342557   //22028664   //21960545 chr7:17384880(+) A-I exon 3'UTR    15342557   //22028664 chr7:17384882(+) A-I exon 3'UTR    15342557 chr7:17384887(+) A-I exon 3'UTR    15342557   //22028664   //21960545   //22327324 chr7:17384940(+) A-I exon 3'UTR    15342557 chr7:17384845(+) A-I intron -    22028664 chr7:17384860(+) A-I intron -    22028664 chr7:17350176(+) G-T intron -    22484847 chr7:17350232(+) C-T intron -    22484847 chr7:17384272(+) G-T intron -    22484847 chr7:17384334(+) A-G intron -    22484847 chr7:17384353(+) A-G intron -    22484847 chr7:17384354(+) A-G intron -    22484847 chr7:17384358(+) A-G intron -    22484847 chr7:17384371(+) A-G intron -    22484847 chr7:17384393(+) A-G intron -    22484847 chr7:17384395(+) A-G intron -    22484847 chr7:17384428(+) A-G intron -    22484847 chr7:17384437(+) A-G intron -    22484847 chr7:17384440(+) A-G intron -    22484847 chr7:17384441(+) A-G intron -    22484847 chr7:17384453(+) A-G intron -    22484847 chr7:17384504(+) T-C intron -    22484847 chr7:17384514(+) A-G intron -    22484847 chr7:17384515(+) A-G intron -    22484847 chr7:17384527(+) A-G intron -    22484847 chr7:17384669(+) A-G intron -    22484847 chr7:17384677(+) A-G intron -    22484847 chr7:17384685(+) A-G intron -    22484847 chr7:17384686(+) A-G intron -    22484847 chr7:17384691(+) A-G intron -    22484847 chr7:17384694(+) A-G intron -    22484847 chr7:17384730(+) A-G intron -    22484847 chr7:17384763(+) A-G intron -    22484847 chr7:17384774(+) A-G intron -    22484847 chr7:17384777(+) A-G intron -    22484847 chr7:17384778(+) A-G intron -    22484847 chr7:17384779(+) A-G intron -    22484847 chr7:17384780(+) A-G intron -    22484847 chr7:17384781(+) A-G intron -    22484847 chr7:17384783(+) A-G intron -    22484847 chr7:17384792(+) A-G intron -    22484847 chr7:17384811(+) A-G intron -    22484847 chr7:17384818(+) A-G intron -    22484847 chr7:17384828(+) A-G intron -    22484847 chr7:17384832(+) A-G intron -    22484847 chr7:17384860(+) A-G intron -    22484847 chr7:17384880(+) A-G intron -    22484847 chr7:17384882(+) A-G intron -    22484847 chr7:17384887(+) A-G intron -    22484847 chr7:17384889(+) A-G intron -    22484847 chr7:17384926(+) A-G intron -    22484847 chr7:17384941(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	AHR	chr7:17338323-17338324(+) m6A 5'UTR       24284625//25456834//24981863//22608085 chr7:17338337-17338338(+) m6A 5'UTR       24284625//25456834//24981863//22575960//22608085 chr7:17338381-17338382(+) m6A 5'UTR       24284625//25456834//24981863//22575960//22608085 chr7:17338790-17338791(+) m6A 5'UTR       24284625 chr7:17338839-17338840(+) m6A 5'UTR       24284625 chr7:17338892-17338893(+) m6A CDS       24284625 chr7:17349615-17349616(+) m6A CDS       26404942 chr7:17349636-17349637(+) m6A CDS       26404942 chr7:17349687-17349688(+) m6A CDS       26404942 chr7:17373573-17373574(+) m6A CDS//exon       27773535 chr7:17373673-17373674(+) m6A CDS       27773535 chr7:17375409-17375410(+) Cm CDS//exon       - chr7:17378622-17378623(+) m6A CDS//exon       24284625//24981863 chr7:17378739-17378740(+) m6A CDS//exon       24284625//25456834//24981863//26404942//27773535//22575960//22608085 chr7:17378764-17378765(+) m6A CDS//exon       24284625//25456834//24981863//26404942//27773535//22575960//22608085 chr7:17378794-17378795(+) m6A CDS//exon       24284625//25456834//24981863//26404942//27773535//22575960//22608085 chr7:17378896-17378897(+) m6A CDS//exon       24284625//24981863//26404942//27773535//22575960//22608085 chr7:17378978-17378979(+) m6A CDS//exon       24284625//25456834//24981863//26404942//27773535//22575960//22608085 chr7:17379010-17379011(+) m6A CDS//exon       24284625//25456834//24981863//26404942//27773535//22575960//22608085 chr7:17379055-17379056(+) m6A CDS//exon       24284625//25456834//24981863//26404942//27773535//22575960//22608085 chr7:17379082-17379083(+) m6A CDS//exon       24284625//25456834//24981863//26404942//27773535//22575960//22608085 chr7:17379103-17379104(+) m6A CDS//exon       24284625//25456834//24981863//26404942//27773535//22575960//22608085 chr7:17379110-17379111(+) m6A CDS//exon       24284625//24981863//26404942//27773535//22575960//22608085 chr7:17379169-17379170(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:17379271-17379272(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:17379293-17379294(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:17379308-17379309(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:17379412-17379413(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:17379451-17379452(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:17379478-17379479(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:17379544-17379545(+) m6A CDS       24284625//24981863//26404942//27773535//22575960//22608085 chr7:17379601-17379602(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:17379623-17379624(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:17379688-17379689(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:17379735-17379736(+) m6A CDS       24284625//24981863//26404942//22608085 chr7:17379779-17379780(+) m6A CDS       24284625//24981863//27773535//22608085 chr7:17379847-17379848(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:17382568-17382569(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:17382607-17382608(+) m6A CDS       24284625//24981863//27773535//22608085 chr7:17382651-17382652(+) m6A CDS       24284625//24981863//27773535//22608085 chr7:17382755-17382756(+) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085 chr7:17382823-17382824(+) m6A 3'UTR       24284625//24981863//22608085 chr7:17384110-17384111(+) m6A 3'UTR//intron       27773535 chr7:17384137-17384138(+) m6A 3'UTR//intron       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3662	Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     - Mitochondrion Cell line (HEK-293|HeLa)     22984580
	AHR	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol HeLa-S3 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Colon cancer cells     24393600 Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3662
Interactor2: AHR

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.