Detail Information

Basic Information:


  VIRBase ID:  

HHID00073395

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3653-3p CFL2
miRBase
Accession/Entrez ID		 MIMAT0018073 1073
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - NEM7

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CFL2
chr14:35179597-35179598(-) m6A 3'UTR       27773535
chr14:35179614-35179615(-) m6A 3'UTR       27773535
chr14:35181516-35181517(-) Y 3'UTR       26075521
chr14:35181827-35181828(-) m6A 3'UTR       26404942
chr14:35181863-35181864(-) m6A 3'UTR       26404942
chr14:35181892-35181893(-) m6A 3'UTR       26404942
chr14:35182079-35182080(-) m6A 3'UTR//CDS       24981863//26404942
chr14:35182118-35182119(-) Gm 3'UTR//CDS       -
chr14:35182137-35182138(-) m6A 3'UTR//CDS       24981863//26404942
chr14:35182175-35182176(-) m6A 3'UTR//CDS       24981863//26404942
chr14:35182477-35182478(-) m6A CDS//intron       27773535
chr14:35182499-35182500(-) m6A CDS//intron       27773535
chr14:35182573-35182574(-) m6A CDS//intron       24981863//26404942//27773535//22608085
chr14:35182635-35182636(-) m6A CDS//intron       24981863//27773535//22608085
chr14:35182942-35182943(-) m6A 5'UTR//intron       24981863//22608085
chr14:35182979-35182980(-) m6A 5'UTR//intron       24981863
chr14:35183934-35183935(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3653-3p
Exosome Plasma     23663360
Mitochondrion Cell line (HEK-293)     22984580
CFL2
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HeLa-S3 cells     -
Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3653-3p
Interactor2: CFL2

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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