Basic Information:

  VIRBase ID:  

HHID00073201

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3613-5p:  MIMAT0017990          RPF1:  NM_025065     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3613-5p	RPF1
miRBase Accession/Entrez ID	MIMAT0017990	80135
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	BXDC5

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3613-5p	rs1279899144 chr13:49996468    C/A rs1327340301 chr13:49996476    A/G rs1363404935 chr13:49996465    G/A rs1438135163 chr13:49996469    A/C rs201796222 chr13:49996468    CA/CAA rs201796222 chr13:49996468    CA/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RPF1	chr1:84959074(+) A-I      intronic chr1:84959056(+) A-I      intronic chr1:84959110(+) A-I      intronic chr1:84959128(+) A-I      intronic chr1:84952059(+) A-I      intronic chr1:84952021(+) A-I      intronic chr1:84950486(+) A-I      intronic chr1:84950502(+) A-I      intronic chr1:84952113(+) A-I      intronic chr1:84950607(+) A-I      intronic chr1:84952002(+) A-I      intronic chr1:84950578(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RPF1	chr1:84944961-84944962(+) m6A 5'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr1:84945035-84945036(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr1:84945139-84945140(+) m6A CDS       24981863//22575960 chr1:84945176-84945177(+) m6A CDS       24981863//27773535 chr1:84946661-84946662(+) m6A CDS       24981863//27773535 chr1:84948621-84948622(+) m6A CDS       24981863//27773535 chr1:84948651-84948652(+) m6A CDS       24981863 chr1:84948661-84948662(+) m6A CDS       24981863 chr1:84961965-84961966(+) m6A CDS       27773535 chr1:84961971-84961972(+) m6A CDS       27773535 chr1:84962011-84962012(+) m6A CDS       27773535 chr1:84963185-84963186(+) m6A 3'UTR       26404942//27773535 chr1:84963200-84963201(+) m6A 3'UTR       26404942//27773535 chr1:84963261-84963262(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3613-5p	Exosome Pooled sera     27278097 Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	RPF1	Chromatin K562 cells     - Exosome Blood     - Nucleus HCC cell line (HepG2)     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3613-5p
Interactor2: RPF1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.