Basic Information:

  VIRBase ID:  

HHID00073041

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3609:  MIMAT0017986          VTI1B:  NM_006370     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3609	VTI1B
miRBase Accession/Entrez ID	MIMAT0017986	10490
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	v-SNARE//VTI1//VTI1-LIKE//vti1-rp1//VTI1L//VTI2

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3609	rs1201010739 chr7:98881721    C/A rs1379314154 chr7:98881711    G/T rs1433840969 chr7:98881723    G/A rs1360895354 chr7:98881703    A/C rs955400524 chr7:98881707    A/G rs955400524 chr7:98881707    A/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	VTI1B	chr14:68131382(-) A-I      intronic chr14:68136089(-) A-I      intronic chr14:68129509(-) A-I      intronic chr14:68136587(-) A-I      intronic chr14:68136279(-) A-I      intronic chr14:68139427(-) A-I      intronic chr14:68139432(-) A-I      intronic chr14:68132189(-) A-I      intronic chr14:68129497(-) A-I      intronic chr14:68137378(-) A-I      intronic chr14:68132228(-) A-I      intronic chr14:68132240(-) A-I      intronic chr14:68131412(-) A-I      intronic chr14:68131384(-) A-I      intronic chr14:68139439(-) A-I      intronic chr14:68125202(-) A-I      intronic chr14:68132250(-) A-I      intronic chr14:68136079(-) A-I      intronic chr14:68134659(-) A-I      intronic chr14:68137422(-) A-I      intronic chr14:68136674(-) A-I      intronic chr14:68132121(-) A-I      intronic chr14:68131705(-) A-I      intronic chr14:68137998(-) A-I      intronic chr14:68134549(-) A-I      intronic chr14:68128523(-) A-I      intronic chr14:68130226(-) A-I      intronic chr14:68134539(-) A-I      intronic chr14:68132158(-) A-I      intronic chr14:68138903(-) A-I      intronic chr14:68125192(-) A-I      intronic chr14:68128761(-) A-I      intronic chr14:68139339(-) A-I      intronic chr14:68128285(-) A-I      intronic chr14:68131351(-) A-I      intronic chr14:68137434(-) A-I      intronic chr14:68136230(-) A-I      intronic chr14:68137449(-) A-I      intronic chr14:68128524(-) A-I      intronic chr14:68129429(-) A-I      intronic chr14:68128765(-) A-I      intronic chr14:68140055(-) A-I      intronic chr14:68128829(-) A-I      intronic chr14:68137344(-) A-I      intronic chr14:68129453(-) A-I      intronic chr14:68140047(-) A-I      intronic chr14:68130279(-) A-I      intronic chr14:68130388(-) A-I      intronic chr14:68134537(-) A-I      intronic chr14:68137302(-) A-I      intronic chr14:68129537(-) A-I      intronic chr14:68139998(-) A-I      intronic chr14:68132168(-) A-I      intronic chr14:68139985(-) A-I      intronic chr14:68131387(-) A-I      intronic chr14:68139877(-) A-I      intronic chr14:68130307(-) A-I      intronic chr14:68136560(-) A-I      intronic chr14:68139354(-) A-I      intronic chr14:68139348(-) A-I      intronic chr14:68139292(-) A-I      intronic chr14:68132153(-) A-I      intronic chr14:68130309(-) A-I      intronic chr14:68139284(-) A-I      intronic chr14:68131244(-) A-I      intronic chr14:68131676(-) A-I      intronic chr14:68131346(-) A-I      intronic chr14:68139252(-) A-I      intronic chr14:68131708(-) A-I      intronic chr14:68131386(-) A-I      intronic chr14:68131787(-) A-I      intronic chr14:68131247(-) A-I      intronic chr14:68131849(-) A-I      intronic chr14:68139215(-) A-I      intronic chr14:68138199(-) A-I      intronic chr14:68138197(-) A-I      intronic chr14:68130328(-) A-I      intronic chr14:68138191(-) A-I      intronic chr14:68131834(-) A-I      intronic chr14:68136111(-) A-I      intronic chr14:68137516(-) A-I      intronic chr14:68129512(-) A-I      intronic chr14:68139378(-) A-I      intronic chr14:68139192(-) A-I      intronic chr14:68137415(-) A-I      intronic chr14:68137357(-) A-I      intronic chr14:68129486(-) A-I      intronic chr14:68136730(-) A-I      intronic chr14:68136677(-) A-I      intronic chr14:68136250(-) A-I      intronic chr14:68132117(-) A-I      intronic chr14:68136119(-) A-I      intronic chr14:68132034(-) A-I      intronic chr14:68128423(-) A-I      intronic chr14:68137419(-) A-I      intronic chr14:68138077(-) A-I      intronic chr14:68139176(-) A-I      intronic chr14:68121864(-) A-I      intronic chr14:68131285(-) A-I      intronic chr14:68129499(-) A-I      intronic chr14:68139856(-) A-I      intronic chr14:68128422(-) A-I      intronic chr14:68128310(-) A-I      intronic chr14:68139298(-) A-I      intronic chr14:68132133(-) A-I      intronic chr14:68121087(-) A-I      intronic chr14:68136629(-) A-I      intronic chr14:68139939(-) A-I      intronic chr14:68128413(-) A-I      intronic chr14:68136806(-) A-I      intronic chr14:68137374(-) A-I      intronic chr14:68131324(-) A-I      intronic chr14:68136768(-) A-I      intronic chr14:68132127(-) A-I      intronic chr14:68128680(-) A-I      intronic chr14:68129378(-) A-I      intronic chr14:68131756(-) A-I      intronic chr14:68139979(-) A-I      intronic chr14:68121133(-) A-I      intronic chr14:68138896(-) A-I      intronic chr14:68136124(-) A-I      intronic chr14:68139324(-) A-I      intronic chr14:68139415(-) A-I      intronic chr14:68132140(-) A-I      intronic chr14:68132033(-) A-I      intronic chr14:68136572(-) A-I      intronic chr14:68130201(-) A-I      intronic chr14:68130134(-) A-I      intronic chr14:68140014(-) A-I      intronic chr14:68128617(-) A-I      intronic chr14:68131720(-) A-I      intronic chr14:68132257(-) A-I      intronic chr14:68138237(-) A-I      intronic chr14:68120881(-) A-I      intronic chr14:68120982(-) A-I      intronic chr14:68128869(-) A-I      intronic chr14:68137416(-) A-I      intronic chr14:68136098(-) A-I      intronic chr14:68139091(-) A-I      intronic chr14:68131409(-) A-I      intronic chr14:68139225(-) A-I      intronic chr14:68139888(-) A-I      intronic chr14:68136084(-) A-I      intronic chr14:68138143(-) A-I      intronic chr14:68127045(-) A-I      intronic chr14:68139903(-) A-I      intronic chr14:68132263(-) A-I      intronic chr14:68139108(-) A-I      intronic chr14:68127122(-) A-I      intronic chr14:68132194(-) A-I      intronic chr14:68139353(-) A-I      intronic chr14:68139855(-) A-I      intronic chr14:68138080(-) A-I      intronic chr14:68139013(-) A-I      intronic chr14:68128373(-) A-I      intronic chr14:68139082(-) A-I      intronic chr14:68137384(-) A-I      intronic chr14:68136712(-) A-I      intronic chr14:68139894(-) A-I      intronic chr14:68136648(-) A-I      intronic chr14:68121976(-) A-I      intronic chr14:68128377(-) A-I      intronic chr14:68128419(-) A-I      intronic chr14:68138063(-) A-I      intronic chr14:68131378(-) A-I      intronic chr14:68138974(-) A-I      intronic chr14:68139000(-) A-I      intronic chr14:68136049(-) A-I      intronic chr14:68121077(-) A-I      intronic chr14:68138904(-) A-I      intronic chr14:68128629(-) A-I      intronic chr14:68136717(-) A-I      intronic chr14:68131381(-) A-I      intronic chr14:68131419(-) A-I      intronic chr14:68136158(-) A-I      intronic chr14:68128470(-) A-I      intronic chr14:68128501(-) A-I      intronic chr14:68137423(-) A-I      intronic chr14:68136256(-) A-I      intronic chr14:68137992(-) A-I      intronic chr14:68129458(-) A-I      intronic chr14:68128424(-) A-I      intronic chr14:68139011(-) A-I      intronic chr14:68129513(-) A-I      intronic chr14:68139018(-) A-I      intronic chr14:68130269(-) A-I      intronic chr14:68136210(-) A-I      intronic chr14:68136125(-) A-I      intronic chr14:68139336(-) A-I      intronic chr14:68131218(-) A-I      intronic chr14:68128610(-) A-I      intronic chr14:68137439(-) A-I      intronic chr14:68128509(-) A-I      intronic chr14:68138121(-) A-I      intronic chr14:68137370(-) A-I      intronic chr14:68138944(-) A-I      intronic chr14:68129526(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	VTI1B	chr14:68128617(-) A-G intron -    22484847 chr14:68131849(-) A-G intron -    22484847 chr14:68137384(-) A-G intron -    22484847 chr14:68137423(-) A-G intron -    22484847 chr14:68137992(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	VTI1B	chr14:68113801-68113802(-) m6A 3'UTR       27773535 chr14:68113866-68113867(-) m6A 3'UTR       27773535 chr14:68113913-68113914(-) m6A 3'UTR       27773535//22608085 chr14:68113927-68113928(-) m6A 3'UTR       27773535//22608085 chr14:68113957-68113958(-) m6A 3'UTR       27773535//22608085 chr14:68114021-68114022(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr14:68114030-68114031(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr14:68114056-68114057(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr14:68114067-68114068(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr14:68114157-68114158(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr14:68115971-68115972(-) m6A 3'UTR       - chr14:68116975-68116976(-) m6A 3'UTR       27773535 chr14:68116994-68116995(-) m6A 3'UTR       27773535 chr14:68117334-68117335(-) m6A 3'UTR       27773535 chr14:68117350-68117351(-) m6A 3'UTR       27773535 chr14:68117359-68117360(-) m6A 3'UTR       27773535 chr14:68117422-68117423(-) m6A 3'UTR       27773535 chr14:68117569-68117570(-) m6A 3'UTR       27773535 chr14:68117594-68117595(-) m6A 3'UTR       27773535 chr14:68117658-68117659(-) m6A 3'UTR       27773535 chr14:68117720-68117721(-) m6A 3'UTR       27773535 chr14:68117774-68117775(-) m6A 3'UTR       27773535 chr14:68117819-68117820(-) m6A 3'UTR       27773535 chr14:68117829-68117830(-) m6A 3'UTR       27773535 chr14:68117913-68117914(-) m6A 3'UTR       24981863//28052920//27773535//22608085 chr14:68117927-68117928(-) m6A 3'UTR       24981863//28052920//27773535//22608085 chr14:68117946-68117947(-) m6A 3'UTR       24981863//28052920//27773535//22608085 chr14:68118070-68118071(-) m6A 3'UTR//CDS       24284625//24981863//28052920//27773535//22575960//22608085 chr14:68118076-68118077(-) m6A 3'UTR//CDS       24284625//24981863//28052920//27773535//22575960//22608085 chr14:68118100-68118101(-) m6A 3'UTR//CDS       24284625//24981863//27773535//22608085 chr14:68123157-68123158(-) m6A 3'UTR//CDS       - chr14:68123165-68123166(-) m6A 3'UTR//CDS       - chr14:68123206-68123207(-) m6A 3'UTR//CDS//exon       - chr14:68123253-68123254(-) m6A 3'UTR//CDS//exon       27773535//22575960 chr14:68126487-68126488(-) m6A 3'UTR//CDS//exon       27773535 chr14:68126543-68126544(-) m6A 3'UTR//CDS//exon       27773535//27371828 chr14:68126553-68126554(-) m6A 3'UTR//CDS//exon       27773535//27371828 chr14:68126565-68126566(-) m6A 3'UTR//CDS//exon       27773535//27371828 chr14:68126589-68126590(-) m6A 3'UTR//CDS//exon       24981863//27773535//27371828//27773536 chr14:68126674-68126675(-) m6A exon//intron       28052920//27773535//27371828//27773536 chr14:68126706-68126707(-) m6A exon//intron       27773535//27371828//27773536 chr14:68129764-68129765(-) m6A 3'UTR//intron       24981863//28052920//27773535//27371828//27773536 chr14:68129780-68129781(-) m6A 3'UTR//intron       24981863//28052920//27773535//27371828//27773536 chr14:68129859-68129860(-) m6A 3'UTR//intron       24981863//27773535//27371828//27773536 chr14:68141094-68141095(-) m6A CDS       27773535//27371828//27773536 chr14:68141135-68141136(-) m6A CDS       27371828//27773536 chr14:68141356-68141357(-) m6A 5'UTR       24981863//27773536//22608085 chr14:68141517-68141518(-) m6A 5'UTR       25456834//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3609	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)     -
	VTI1B	Chromatin K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3609
Interactor2: VTI1B

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.