Detail Information

Basic Information:


  VIRBase ID:  

HHID00073038

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3609:           WDR1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3609 WDR1
miRBase
Accession/Entrez ID		 MIMAT0017986 9948
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - AIP1//HEL-S-52//NORI-1//PFITS

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3609
rs1201010739 chr7:98881721    C/A
rs1379314154 chr7:98881711    G/T
rs1433840969 chr7:98881723    G/A
rs1360895354 chr7:98881703    A/C
rs955400524 chr7:98881707    A/G
rs955400524 chr7:98881707    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR WDR1
chr4:10114850(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED WDR1
chr4:10087572(-) A-I intron -    21960545
chr4:10089146(-) A-I intron -    21960545
chr4:10075985(-) T-A exon 3'UTR    21725310

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase WDR1
chr4:10076719-10076720(-) m6A 3'UTR       24981863//27773535
chr4:10076735-10076736(-) m6A 3'UTR       24981863//27773535
chr4:10076752-10076753(-) m6A 3'UTR       27773535
chr4:10076775-10076776(-) m6A 3'UTR//exon       27773535
chr4:10076816-10076817(-) m6A 3'UTR//exon       27773535
chr4:10076940-10076941(-) m6A 3'UTR//exon       24284625//24981863//28052920//26404942//27773535//27371828//22575960
chr4:10076962-10076963(-) m6A 3'UTR//exon       24284625//24981863//28052920//26404942//27773535//27371828//27773536//22575960
chr4:10076974-10076975(-) m6A 3'UTR//exon       24284625//24981863//28052920//26404942//27773535//27371828//27773536//22575960
chr4:10077015-10077016(-) m6A CDS//exon       24284625//24981863//28052920//26404942//27773535//27371828//27773536//22575960
chr4:10077390-10077391(-) m6A exon//intron       24284625//27371828//27773536//22575960
chr4:10077404-10077405(-) m6A exon//intron       24284625
chr4:10077730-10077731(-) m6A exon//intron       27371828
chr4:10077756-10077757(-) m6A exon//intron       27371828
chr4:10078766-10078767(-) m6A exon//intron       22575960
chr4:10078936-10078937(-) Am CDS//exon       -
chr4:10078945-10078946(-) m6A CDS//exon       22575960
chr4:10078963-10078964(-) m6A CDS//exon       22575960
chr4:10078983-10078984(-) m6A CDS//exon       22575960
chr4:10079006-10079007(-) m6A CDS//exon       22575960
chr4:10079013-10079014(-) m6A CDS//exon       22575960
chr4:10079051-10079052(-) m6A CDS//exon       22575960
chr4:10079067-10079068(-) m6A CDS//exon       22575960
chr4:10080536-10080537(-) m6A CDS//exon       24284625//27773536//22575960
chr4:10082983-10082984(-) m6A CDS//exon       24284625//22575960
chr4:10083049-10083050(-) m6A CDS//exon       24284625//27773535//22575960
chr4:10083064-10083065(-) m6A CDS//exon       24284625//27773535//22575960
chr4:10084651-10084652(-) m6A CDS//exon       24284625//27773535//22575960
chr4:10084744-10084745(-) m6A CDS//exon       24284625//24981863//26404942//27773535//22575960
chr4:10086073-10086074(-) m6A CDS//exon       24981863//26404942//27773535//22575960
chr4:10089361-10089362(-) m6A CDS//exon       27773535//22575960
chr4:10089367-10089368(-) m6A CDS//exon       27773535//22575960
chr4:10089412-10089413(-) m6A CDS//exon       -
chr4:10089442-10089443(-) m6A CDS//exon       -
chr4:10089975-10089976(-) m6A CDS//exon       27773535//22575960
chr4:10090318-10090319(-) m6A CDS//exon       27773535//22575960
chr4:10093160-10093161(-) m6A exon//intron       27773535
chr4:10093167-10093168(-) m6A exon//intron       27773535
chr4:10093174-10093175(-) m6A exon//intron       27773535
chr4:10093352-10093353(-) m6A exon//intron       25456834//27371828
chr4:10093377-10093378(-) m6A exon//intron       25456834//27371828
chr4:10093410-10093411(-) m6A exon//intron       25456834//27371828
chr4:10093417-10093418(-) m6A exon//intron       25456834//27371828
chr4:10093427-10093428(-) m6A exon//intron       25456834
chr4:10093436-10093437(-) m6A exon//intron       25456834
chr4:10098237-10098238(-) m6A exon//intron       24981863//27773535//27371828
chr4:10099364-10099365(-) m6A CDS//exon//intron       24981863//27773535//27371828
chr4:10099434-10099435(-) m6A CDS//exon//intron       24981863//26404942//27773535//27371828//22575960
chr4:10099460-10099461(-) m6A CDS//exon//intron       24981863//26404942//27773535//27371828//22575960
chr4:10100654-10100655(-) m6A CDS//exon//intron       26404942//27773535//22575960
chr4:10100661-10100662(-) m6A CDS//exon//intron       26404942//27773535//22575960
chr4:10100672-10100673(-) m6A CDS//exon//intron       26404942//27773535//22575960
chr4:10108074-10108075(-) m6A exon//intron       27773535//22575960
chr4:10117743-10117744(-) m6A CDS//exon       27371828//27773536//22575960
chr4:10117940-10117941(-) m6A 5'UTR//intron       24981863//27371828//27773536
chr4:10118109-10118110(-) m6A exon//intron       24981863
chr4:10118429-10118430(-) m6A 5'UTR//exon       24981863//27371828//27773536
chr4:10118508-10118509(-) m6A 5'UTR       24981863//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3609
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)     -
WDR1
Chromatin K562 cells     -
Cytosol HeLa-S3 cells|K562 cells     -
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3609
Interactor2: WDR1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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