Basic Information:

  VIRBase ID:  

HHID00073036

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3609:  MIMAT0017986          NUP58:  NM_014089     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3609	NUP58
miRBase Accession/Entrez ID	MIMAT0017986	9818
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	NUP45//NUPL1//PRO2463

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3609	rs1201010739 chr7:98881721    C/A rs1379314154 chr7:98881711    G/T rs1433840969 chr7:98881723    G/A rs1360895354 chr7:98881703    A/C rs955400524 chr7:98881707    A/G rs955400524 chr7:98881707    A/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	NUP58	chr13:25915046(+) A-I      3'UTR chr13:25915013(+) A-I      3'UTR chr13:25892407(+) A-I      intronic chr13:25892147(+) A-I      intronic chr13:25904100(+) A-I      intronic chr13:25892102(+) A-I      intronic chr13:25892131(+) A-I      intronic chr13:25915045(+) A-I      3'UTR chr13:25892386(+) A-I      intronic chr13:25878141(+) A-I      intronic chr13:25891088(+) A-I      intronic chr13:25899988(+) A-I      intronic chr13:25879555(+) A-I      intronic chr13:25888718(+) A-I      intronic chr13:25902077(+) A-I      intronic chr13:25902135(+) A-I      intronic chr13:25902153(+) A-I      intronic chr13:25879560(+) A-I      intronic chr13:25902176(+) A-I      intronic chr13:25902183(+) A-I      intronic chr13:25902187(+) A-I      intronic chr13:25902190(+) A-I      intronic chr13:25892387(+) A-I      intronic chr13:25902595(+) A-I      intronic chr13:25902614(+) A-I      intronic chr13:25902673(+) A-I      intronic chr13:25888572(+) A-I      intronic chr13:25888226(+) A-I      intronic chr13:25880289(+) A-I      intronic chr13:25881451(+) A-I      intronic chr13:25892398(+) A-I      intronic chr13:25892021(+) A-I      intronic chr13:25881454(+) A-I      intronic chr13:25888153(+) A-I      intronic chr13:25888305(+) A-I      intronic chr13:25888333(+) A-I      intronic chr13:25888578(+) A-I      intronic chr13:25888633(+) A-I      intronic chr13:25902735(+) A-I      intronic chr13:25892053(+) A-I      intronic chr13:25888650(+) A-I      intronic chr13:25892088(+) A-I      intronic chr13:25902634(+) A-I      intronic chr13:25892493(+) A-I      intronic chr13:25895830(+) A-I      intronic chr13:25888713(+) A-I      intronic chr13:25888657(+) A-I      intronic chr13:25888765(+) A-I      intronic chr13:25888624(+) A-I      intronic chr13:25892355(+) A-I      intronic chr13:25892120(+) A-I      intronic chr13:25880463(+) A-I      intronic chr13:25878889(+) A-I      intronic chr13:25878929(+) A-I      intronic chr13:25879508(+) A-I      intronic chr13:25888785(+) A-I      intronic chr13:25899950(+) A-I      intronic chr13:25888778(+) A-I      intronic chr13:25914919(+) A-I      3'UTR chr13:25891057(+) A-I      intronic chr13:25881455(+) A-I      intronic chr13:25881392(+) A-I      intronic chr13:25892114(+) A-I      intronic chr13:25888353(+) A-I      intronic chr13:25879346(+) A-I      intronic chr13:25880455(+) A-I      intronic chr13:25891055(+) A-I      intronic chr13:25902089(+) A-I      intronic chr13:25880449(+) A-I      intronic chr13:25892363(+) A-I      intronic chr13:25902803(+) A-I      intronic chr13:25879351(+) A-I      intronic chr13:25888068(+) A-I      intronic chr13:25888345(+) A-I      intronic chr13:25879561(+) A-I      intronic chr13:25891637(+) A-I      intronic chr13:25891636(+) A-I      intronic chr13:25902084(+) A-I      intronic chr13:25892119(+) A-I      intronic chr13:25891087(+) A-I      intronic chr13:25891680(+) A-I      intronic chr13:25899972(+) A-I      intronic chr13:25891706(+) A-I      intronic chr13:25892213(+) A-I      intronic chr13:25880464(+) A-I      intronic chr13:25892144(+) A-I      intronic chr13:25891640(+) A-I      intronic chr13:25902724(+) A-I      intronic chr13:25880511(+) A-I      intronic chr13:25879543(+) A-I      intronic chr13:25888579(+) A-I      intronic chr13:25878755(+) A-I      intronic chr13:25891058(+) A-I      intronic chr13:25902699(+) A-I      intronic chr13:25880396(+) A-I      intronic chr13:25892082(+) A-I      intronic chr13:25895932(+) A-I      intronic chr13:25902177(+) A-I      intronic chr13:25892052(+) A-I      intronic chr13:25891676(+) A-I      intronic chr13:25891666(+) A-I      intronic chr13:25880422(+) A-I      intronic chr13:25888686(+) A-I      intronic chr13:25902709(+) A-I      intronic chr13:25891036(+) A-I      intronic chr13:25888208(+) A-I      intronic chr13:25880420(+) A-I      intronic chr13:25888694(+) A-I      intronic chr13:25879213(+) A-I      intronic chr13:25892141(+) A-I      intronic chr13:25888712(+) A-I      intronic chr13:25892411(+) A-I      intronic chr13:25888291(+) A-I      intronic chr13:25892345(+) A-I      intronic chr13:25891653(+) A-I      intronic chr13:25892421(+) A-I      intronic chr13:25914976(+) A-I      3'UTR chr13:25914965(+) A-I      3'UTR chr13:25914971(+) A-I      3'UTR chr13:25914933(+) A-I      3'UTR chr13:25914840(+) A-I      3'UTR chr13:25914977(+) A-I      3'UTR

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	NUP58	chr13:25875870-25875871(+) m6A 5'UTR//exon       24981863 chr13:25875909-25875910(+) m6A 5'UTR//exon       24981863 chr13:25906220-25906221(+) m6A 3'UTR//intron       24981863 chr13:25906240-25906241(+) m6A 3'UTR//intron       24981863 chr13:25914209-25914210(+) m6A CDS//intron       25456834//24981863 chr13:25914217-25914218(+) m6A CDS//intron       25456834//24981863 chr13:25914238-25914239(+) m6A CDS//intron       25456834//24981863 chr13:25914252-25914253(+) m6A CDS//intron       25456834//24981863 chr13:25914272-25914273(+) m6A 3'UTR//intron       25456834//24981863 chr13:25914860-25914861(+) m6A 3'UTR//intron       - chr13:25914879-25914880(+) m6A 3'UTR//intron       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3609	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)     -
	NUP58	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3609
Interactor2: NUP58

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.