Detail Information

Basic Information:


  VIRBase ID:  

HHID00073033

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3609:           MKNK1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3609 MKNK1
miRBase
Accession/Entrez ID		 MIMAT0017986 8569
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - MNK1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3609
rs1201010739 chr7:98881721    C/A
rs1379314154 chr7:98881711    G/T
rs1433840969 chr7:98881723    G/A
rs1360895354 chr7:98881703    A/C
rs955400524 chr7:98881707    A/G
rs955400524 chr7:98881707    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MKNK1
chr1:47037119(-) A-I      NonSyn:Thr->Ala
chr1:47030286(-) A-I      intronic
chr1:47030293(-) A-I      intronic
chr1:47030305(-) A-I      intronic
chr1:47032797(-) A-I      intronic
chr1:47030321(-) A-I      intronic
chr1:47052749(-) A-I      intronic
chr1:47052657(-) A-I      intronic
chr1:47030371(-) A-I      intronic
chr1:47030324(-) A-I      intronic
chr1:47059327(-) A-I      intronic
chr1:47059326(-) A-I      intronic
chr1:47059027(-) A-I      intronic
chr1:47052728(-) A-I      intronic
chr1:47052601(-) A-I      intronic
chr1:47052569(-) A-I      intronic
chr1:47052577(-) A-I      intronic
chr1:47059339(-) A-I      intronic
chr1:47037106(-) A-I      NonSyn:Gln->Arg
chr1:47052531(-) A-I      intronic
chr1:47032803(-) A-I      intronic
chr1:47054315(-) A-I      intronic
chr1:47059446(-) A-I      intronic
chr1:47059406(-) A-I      intronic
chr1:47059388(-) A-I      intronic
chr1:47059314(-) A-I      intronic
chr1:47059065(-) A-I      intronic
chr1:47059003(-) A-I      intronic
chr1:47058968(-) A-I      intronic
chr1:47057908(-) A-I      intronic
chr1:47057738(-) A-I      intronic
chr1:47054392(-) A-I      intronic
chr1:47054369(-) A-I      intronic
chr1:47054331(-) A-I      intronic
chr1:47054330(-) A-I      intronic
chr1:47053403(-) A-I      intronic
chr1:47054312(-) A-I      intronic
chr1:47053450(-) A-I      intronic
chr1:47053407(-) A-I      intronic
chr1:47033545(-) A-I      intronic
chr1:47032890(-) A-I      intronic
chr1:47032887(-) A-I      intronic
chr1:47032881(-) A-I      intronic
chr1:47032858(-) A-I      intronic
chr1:47032815(-) A-I      intronic
chr1:47032752(-) A-I      intronic
chr1:47030393(-) A-I      intronic
chr1:47067984(-) A-I      intronic
chr1:47032742(-) A-I      intronic
chr1:47032711(-) A-I      intronic
chr1:47053402(-) A-I      intronic
chr1:47053389(-) A-I      intronic
chr1:47053377(-) A-I      intronic
chr1:47053365(-) A-I      intronic
chr1:47032679(-) A-I      intronic
chr1:47030420(-) A-I      intronic
chr1:47030419(-) A-I      intronic
chr1:47060415(-) A-I      intronic
chr1:47060432(-) A-I      intronic
chr1:47060576(-) A-I      intronic
chr1:47067879(-) A-I      intronic
chr1:47067881(-) A-I      intronic
chr1:47030389(-) A-I      intronic
chr1:47030350(-) A-I      intronic
chr1:47029654(-) A-I      intronic
chr1:47029605(-) A-I      intronic
chr1:47029536(-) A-I      intronic
chr1:47029528(-) A-I      intronic
chr1:47029524(-) A-I      intronic
chr1:47029492(-) A-I      intronic
chr1:47029475(-) A-I      intronic
chr1:47029474(-) A-I      intronic
chr1:47029473(-) A-I      intronic
chr1:47052628(-) A-I      intronic
chr1:47053317(-) A-I      intronic
chr1:47053273(-) A-I      intronic
chr1:47053246(-) A-I      intronic
chr1:47052714(-) A-I      intronic
chr1:47052709(-) A-I      intronic
chr1:47052686(-) A-I      intronic
chr1:47052683(-) A-I      intronic
chr1:47052661(-) A-I      intronic
chr1:47052660(-) A-I      intronic
chr1:47052651(-) A-I      intronic
chr1:47052612(-) A-I      intronic
chr1:47052586(-) A-I      intronic
chr1:47052519(-) A-I      intronic
chr1:47043005(-) A-I      intronic
chr1:47043004(-) A-I      intronic
chr1:47042988(-) A-I      intronic
chr1:47038022(-) A-I      intronic
chr1:47033792(-) A-I      intronic
chr1:47033685(-) A-I      intronic
chr1:47033628(-) A-I      intronic
chr1:47033605(-) A-I      intronic
chr1:47061526(-) A-I      intronic
chr1:47059274(-) A-I      intronic
chr1:47059009(-) A-I      intronic
chr1:47058947(-) A-I      intronic
chr1:47053247(-) A-I      intronic
chr1:47059031(-) A-I      intronic
chr1:47057849(-) A-I      intronic
chr1:47053426(-) A-I      intronic
chr1:47059465(-) A-I      intronic
chr1:47061593(-) A-I      intronic
chr1:47052755(-) A-I      intronic
chr1:47054235(-) A-I      intronic
chr1:47059416(-) A-I      intronic
chr1:47060590(-) A-I      intronic
chr1:47066861(-) A-I      intronic
chr1:47044720(-) A-I      intronic
chr1:47052664(-) A-I      intronic
chr1:47053476(-) A-I      intronic
chr1:47059343(-) A-I      intronic
chr1:47052654(-) A-I      intronic
chr1:47053488(-) A-I      intronic
chr1:47060577(-) A-I      intronic
chr1:47053327(-) A-I      intronic
chr1:47058923(-) A-I      intronic
chr1:47057829(-) A-I      intronic
chr1:47057898(-) A-I      intronic
chr1:47059268(-) A-I      intronic
chr1:47058936(-) A-I      intronic
chr1:47033686(-) A-I      intronic
chr1:47061647(-) A-I      intronic
chr1:47061595(-) A-I      intronic
chr1:47059019(-) A-I      intronic
chr1:47058999(-) A-I      intronic
chr1:47052546(-) A-I      intronic
chr1:47061521(-) A-I      intronic
chr1:47052685(-) A-I      intronic
chr1:47064669(-) A-I      intronic
chr1:47032738(-) A-I      intronic
chr1:47059522(-) A-I      intronic
chr1:47054367(-) A-I      intronic
chr1:47053367(-) A-I      intronic
chr1:47060408(-) A-I      intronic
chr1:47053406(-) A-I      intronic
chr1:47052608(-) A-I      intronic
chr1:47066862(-) A-I      intronic
chr1:47042894(-) A-I      intronic
chr1:47053286(-) A-I      intronic
chr1:47042949(-) A-I      intronic
chr1:47064328(-) A-I      intronic
chr1:47053340(-) A-I      intronic
chr1:47052008(-) A-I      intronic
chr1:47057677(-) A-I      intronic
chr1:47052591(-) A-I      intronic
chr1:47064322(-) A-I      intronic
chr1:47059471(-) A-I      intronic
chr1:47058981(-) A-I      intronic
chr1:47052746(-) A-I      intronic
chr1:47052506(-) A-I      intronic
chr1:47058943(-) A-I      intronic
chr1:47044609(-) A-I      intronic
chr1:47060573(-) A-I      intronic
chr1:47052595(-) A-I      intronic
chr1:47052618(-) A-I      intronic
chr1:47038009(-) A-I      intronic
chr1:47061486(-) A-I      intronic
chr1:47059428(-) A-I      intronic
chr1:47059030(-) A-I      intronic
chr1:47060475(-) A-I      intronic
chr1:47052585(-) A-I      intronic
chr1:47032725(-) A-I      intronic
chr1:47061500(-) A-I      intronic
chr1:47059039(-) A-I      intronic
chr1:47052733(-) A-I      intronic
chr1:47057354(-) A-I      intronic
chr1:47053245(-) A-I      intronic
chr1:47057906(-) A-I      intronic
chr1:47053324(-) A-I      intronic
chr1:47052565(-) A-I      intronic
chr1:47052514(-) A-I      intronic
chr1:47030406(-) A-I      intronic
chr1:47057071(-) A-I      intronic
chr1:47057800(-) A-I      intronic
chr1:47053224(-) A-I      intronic
chr1:47052513(-) A-I      intronic
chr1:47043070(-) A-I      intronic
chr1:47059481(-) A-I      intronic
chr1:47066870(-) A-I      intronic
chr1:47044606(-) A-I      intronic
chr1:47061491(-) A-I      intronic
chr1:47064730(-) A-I      intronic
chr1:47061545(-) A-I      intronic
chr1:47060597(-) A-I      intronic
chr1:47061693(-) A-I      intronic
chr1:47052754(-) A-I      intronic
chr1:47053361(-) A-I      intronic
chr1:47057740(-) A-I      intronic
chr1:47060410(-) A-I      intronic
chr1:47059452(-) A-I      intronic
chr1:47057799(-) A-I      intronic
chr1:47057655(-) A-I      intronic
chr1:47064503(-) A-I      intronic
chr1:47052771(-) A-I      intronic
chr1:47059379(-) A-I      intronic
chr1:47052644(-) A-I      intronic
chr1:47059502(-) A-I      intronic
chr1:47059445(-) A-I      intronic
chr1:47059384(-) A-I      intronic
chr1:47053437(-) A-I      intronic
chr1:47061596(-) A-I      intronic
chr1:47052576(-) A-I      intronic
chr1:47060511(-) A-I      intronic
chr1:47058938(-) A-I      intronic
chr1:47058967(-) A-I      intronic
chr1:47052588(-) A-I      intronic
chr1:47052763(-) A-I      intronic
chr1:47061692(-) A-I      intronic
chr1:47059068(-) A-I      intronic
chr1:47061552(-) A-I      intronic
chr1:47044676(-) A-I      intronic
chr1:47060572(-) A-I      intronic
chr1:47058982(-) A-I      intronic
chr1:47043911(-) A-I      intronic
chr1:47053278(-) A-I      intronic
chr1:47057768(-) A-I      intronic
chr1:47043114(-) A-I      intronic
chr1:47061695(-) A-I      intronic
chr1:47053233(-) A-I      intronic
chr1:47057910(-) A-I      intronic
chr1:47053217(-) A-I      intronic
chr1:47059364(-) A-I      intronic
chr1:47060633(-) A-I      intronic
chr1:47059367(-) A-I      intronic
chr1:47052675(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED MKNK1
chr1:47052514(-) A-I intron -    22327324
chr1:47059019(-) A-I intron -    22327324
chr1:47042949(-) A-G intron -    22484847
chr1:47052514(-) A-G intron -    22484847
chr1:47052565(-) A-G intron -    22484847
chr1:47052618(-) A-G intron -    22484847
chr1:47052685(-) A-G intron -    22484847
chr1:47052733(-) A-G intron -    22484847
chr1:47052746(-) A-G intron -    22484847
chr1:47052771(-) A-G intron -    22484847
chr1:47053367(-) A-G intron -    22484847
chr1:47053406(-) A-G intron -    22484847
chr1:47053476(-) A-G intron -    22484847
chr1:47053488(-) A-G intron -    22484847
chr1:47054367(-) A-G intron -    22484847
chr1:47057906(-) A-G intron -    22484847
chr1:47057910(-) A-G intron -    22484847
chr1:47058943(-) A-G intron -    22484847
chr1:47058981(-) A-G intron -    22484847
chr1:47058999(-) A-G intron -    22484847
chr1:47059009(-) A-G intron -    22484847
chr1:47059019(-) A-G intron -    22484847
chr1:47059030(-) A-G intron -    22484847
chr1:47059031(-) A-G intron -    22484847
chr1:47059068(-) A-G intron -    22484847
chr1:47059268(-) A-G intron -    22484847
chr1:47059367(-) A-G intron -    22484847
chr1:47059416(-) A-G intron -    22484847
chr1:47059445(-) A-G intron -    22484847
chr1:47059465(-) A-G intron -    22484847
chr1:47059481(-) A-G intron -    22484847
chr1:47059522(-) A-G intron -    22484847
chr1:47060572(-) A-G intron -    22484847
chr1:47060573(-) A-G intron -    22484847
chr1:47060577(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MKNK1
chr1:47024271-47024272(-) m6A 3'UTR//CDS       27371828
chr1:47024387-47024388(-) m6A 3'UTR//CDS       24981863//27371828
chr1:47024454-47024455(-) m6A 3'UTR//CDS//exon       24981863//27773535//27371828
chr1:47024469-47024470(-) m6A 3'UTR//CDS//exon       24981863//27773535//27371828
chr1:47025931-47025932(-) m6A 3'UTR//CDS//intron       27773535//27371828
chr1:47027191-47027192(-) m6A 3'UTR//CDS//exon//intron       27371828
chr1:47030755-47030756(-) m6A 3'UTR//CDS//exon       27773535
chr1:47030760-47030761(-) m6A 3'UTR//CDS//exon       27773535
chr1:47037765-47037766(-) Y 3'UTR//CDS//exon       26075521
chr1:47040496-47040497(-) m6A exon//intron       27773535
chr1:47040504-47040505(-) m6A exon//intron       27773535
chr1:47040542-47040543(-) m6A exon//intron       27773535
chr1:47040578-47040579(-) m6A exon//intron       27773535
chr1:47040591-47040592(-) m6A exon//intron       27773535
chr1:47040689-47040690(-) m6A 3'UTR//CDS//exon//intron       27773535
chr1:47040751-47040752(-) m6A exon//intron       27773535
chr1:47042249-47042250(-) m6A 3'UTR//CDS//exon       27773535
chr1:47042314-47042315(-) m6A 3'UTR//CDS//exon       27773535
chr1:47046138-47046139(-) m6A 3'UTR//intron       27773535
chr1:47048984-47048985(-) m6A 3'UTR//5'UTR//CDS//exon       27773535
chr1:47050215-47050216(-) m6A exon//intron       27773535
chr1:47059869-47059870(-) m6A 5'UTR//CDS//exon       -
chr1:47059889-47059890(-) m6A 5'UTR//CDS//exon       -
chr1:47059925-47059926(-) m6A 5'UTR//CDS//exon       -
chr1:47073615-47073616(-) m6A intron       -
chr1:47073653-47073654(-) m6A intron       -
chr1:47073801-47073802(-) m6A intron       24284625//24981863//27773535
chr1:47073813-47073814(-) m6A intron       24284625//24981863//27773535//27371828
chr1:47073882-47073883(-) m6A intron       25456834//24981863//27773535//27371828
chr1:47073925-47073926(-) m6A intron       25456834//24981863//27773535//27371828
chr1:47073953-47073954(-) m6A intron       25456834//24981863//27773535//27371828
chr1:47073999-47074000(-) m6A intron       24981863//27773535//27371828
chr1:47074059-47074060(-) m6A intron       27773535//27371828
chr1:47074071-47074072(-) m6A intron       27773535//27371828
chr1:47074087-47074088(-) m6A intron       27773535//27371828
chr1:47074147-47074148(-) m6A intron       24284625//24981863//27773535//27371828
chr1:47074256-47074257(-) m6A intron       24284625//24981863//27773535
chr1:47074310-47074311(-) m6A intron       24284625//24981863//27773535
chr1:47074323-47074324(-) m6A intron       24284625//24981863
chr1:47074385-47074386(-) m6A intron       24284625//24981863
chr1:47075096-47075097(-) m6A intron       27773535//27371828
chr1:47075117-47075118(-) m6A intron       27773535//27371828
chr1:47075197-47075198(-) m6A intron       24284625//24209618//25456834//24981863//27773535//27371828
chr1:47075260-47075261(-) m6A intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr1:47075283-47075284(-) m6A intron       24284625//24209618//25456834//24981863//27371828//22575960//22608085
chr1:47075313-47075314(-) m6A intron       24284625//24209618//25456834//24981863//27371828//22575960//22608085
chr1:47075695-47075696(-) m6A intron       24284625//25456834//24981863//27371828//22608085
chr1:47075857-47075858(-) m6A intron       24284625//27773535
chr1:47078625-47078626(-) m6A intron       24284625//27371828
chr1:47078740-47078741(-) m6A intron       24209618//25456834//24981863//27371828//22575960
chr1:47078796-47078797(-) m6A intron       24209618//25456834//24981863//27371828//22575960
chr1:47078829-47078830(-) m6A intron       24284625//24209618//24981863//27371828//22575960
chr1:47078865-47078866(-) m6A intron       24284625//27371828
chr1:47078958-47078959(-) m6A intron       24284625//25456834//27371828//27773536
chr1:47079017-47079018(-) m6A intron       24284625//25456834//27371828//27773536
chr1:47079175-47079176(-) m6A intron       25456834//27371828
chr1:47079190-47079191(-) m6A intron       25456834//24981863//27371828
chr1:47079224-47079225(-) m6A intron       25456834//24981863
chr1:47079247-47079248(-) m6A intron       25456834//24981863
chr1:47079265-47079266(-) m6A intron       25456834//24981863
chr1:47079516-47079517(-) m6A intron       25456834
chr1:47079573-47079574(-) m6A intron       -
chr1:47080566-47080567(-) m6A intron       -
chr1:47080622-47080623(-) m6A intron       -
chr1:47080697-47080698(-) m6A intron       -
chr1:47080717-47080718(-) m6A intron       -
chr1:47080896-47080897(-) m6A intron       -
chr1:47080948-47080949(-) m1A intron       26863196
chr1:47080993-47080994(-) m6A intron       27773535
chr1:47081117-47081118(-) m6A intron       -
chr1:47082385-47082386(-) m6A 5'UTR       24209618//25456834//24981863
chr1:47082442-47082443(-) m6A 5'UTR       24209618//25456834//24981863//27371828
chr1:47082456-47082457(-) m6A 5'UTR       24209618//25456834//24981863//27371828
chr1:47082476-47082477(-) m6A 5'UTR       24209618//25456834//24981863//27371828
chr1:47082488-47082489(-) m6A 5'UTR       24209618//25456834//24981863//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3609
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)     -
MKNK1
Chromatin K562 cells     -
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Membrane K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3609
Interactor2: MKNK1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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