Detail Information

Basic Information:


  VIRBase ID:  

HHID00073032

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3609:           TFEB:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3609 TFEB
miRBase
Accession/Entrez ID		 MIMAT0017986 7942
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ALPHATFEB//BHLHE35//TCFEB

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3609
rs1201010739 chr7:98881721    C/A
rs1379314154 chr7:98881711    G/T
rs1433840969 chr7:98881723    G/A
rs1360895354 chr7:98881703    A/C
rs955400524 chr7:98881707    A/G
rs955400524 chr7:98881707    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TFEB
chr6:41693770(-) A-I      intronic
chr6:41693844(-) A-I      intronic
chr6:41694279(-) A-I      intronic
chr6:41694287(-) A-I      intronic
chr6:41694346(-) A-I      intronic
chr6:41694348(-) A-I      intronic
chr6:41695348(-) A-I      intronic
chr6:41695344(-) A-I      intronic
chr6:41695178(-) A-I      intronic
chr6:41694428(-) A-I      intronic
chr6:41693765(-) A-I      intronic
chr6:41695347(-) A-I      intronic
chr6:41693800(-) A-I      intronic
chr6:41694249(-) A-I      intronic
chr6:41694298(-) A-I      intronic
chr6:41694278(-) A-I      intronic
chr6:41693752(-) A-I      intronic
chr6:41694311(-) A-I      intronic
chr6:41694247(-) A-I      intronic
chr6:41657885(-) A-I      intronic
chr6:41694347(-) A-I      intronic
chr6:41689832(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TFEB
chr6:41664401(-) A-G intron -    22484847
chr6:41665146(-) G-T intron -    22484847
chr6:41683414(-) C-T intron -    22484847
chr6:41686085(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TFEB
chr6:41651729-41651730(-) m6A 3'UTR       -
chr6:41651911-41651912(-) m6A 3'UTR       24284625//25456834//24981863//28052920//27371828
chr6:41651986-41651987(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27371828//27773536
chr6:41652192-41652193(-) m6A 3'UTR       24284625//24981863//28052920//27371828
chr6:41652311-41652312(-) m6A 3'UTR       24284625//28052920//27371828
chr6:41652466-41652467(-) m6A CDS       24284625//25456834//24981863//28052920//27773535//27371828//27773536
chr6:41652522-41652523(-) m6A CDS       24284625//25456834//24981863//28052920//27371828//27773536
chr6:41652583-41652584(-) m6A CDS       24284625//24981863//28052920//27371828//27773536
chr6:41652757-41652758(-) m6A CDS       24284625//27371828
chr6:41659012-41659013(-) m6A CDS//intron       27371828//27773536
chr6:41703108-41703109(-) m6A 5'UTR//intron       24209618
chr6:41703149-41703150(-) m6A 5'UTR//intron       24209618

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3609
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)     -
TFEB
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3609
Interactor2: TFEB

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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