Basic Information:

  VIRBase ID:  

HHID00073031

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3609:  MIMAT0017986          SNRPB2:  NM_198220     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3609	SNRPB2
miRBase Accession/Entrez ID	MIMAT0017986	6629
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	Msl1//U2B''

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3609	rs1201010739 chr7:98881721    C/A rs1379314154 chr7:98881711    G/T rs1433840969 chr7:98881723    G/A rs1360895354 chr7:98881703    A/C rs955400524 chr7:98881707    A/G rs955400524 chr7:98881707    A/T

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SNRPB2	chr20:16712876-16712877(+) m6A CDS//exon       27773535 chr20:16712917-16712918(+) m6A CDS//exon       27773535 chr20:16712944-16712945(+) m6A CDS//exon       27773535 chr20:16712974-16712975(+) m6A CDS//exon       27773535 chr20:16713034-16713035(+) m6A exon//intron       27773535 chr20:16713060-16713061(+) m6A exon//intron       27773535 chr20:16717923-16717924(+) m6A CDS       24981863//27773535//22608085 chr20:16717956-16717957(+) m6A CDS       24981863//27773535//22608085 chr20:16718001-16718002(+) m6A CDS       24981863//27773535//22608085 chr20:16718009-16718010(+) m6A CDS       24981863//27773535//22608085 chr20:16718029-16718030(+) m6A CDS       24981863//27773535//22608085 chr20:16719499-16719500(+) m6A CDS       24981863//27773535//22608085 chr20:16720988-16720989(+) m6A CDS       27773535 chr20:16721023-16721024(+) m6A CDS       27773535 chr20:16721675-16721676(+) m6A 3'UTR       27773535 chr20:16721772-16721773(+) m6A 3'UTR       27773535 chr20:16721807-16721808(+) m6A 3'UTR       27773535 chr20:16721843-16721844(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3609	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)     -
	SNRPB2	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleus HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3609
Interactor2: SNRPB2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.