Basic Information:

  VIRBase ID:  

HHID00073030

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3609:  MIMAT0017986          MSMO1:  NM_006745     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3609	MSMO1
miRBase Accession/Entrez ID	MIMAT0017986	6307
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	DESP4//ERG25//MCCPD//SC4MOL

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3609	rs1201010739 chr7:98881721    C/A rs1379314154 chr7:98881711    G/T rs1433840969 chr7:98881723    G/A rs1360895354 chr7:98881703    A/C rs955400524 chr7:98881707    A/G rs955400524 chr7:98881707    A/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MSMO1	chr4:166252398(+) A-I      intronic chr4:166252308(+) A-I      intronic chr4:166252307(+) A-I      intronic chr4:166252295(+) A-I      intronic chr4:166263756(+) A-I      3'UTR chr4:166263791(+) A-I      3'UTR chr4:166263718(+) A-I      3'UTR chr4:166263729(+) A-I      3'UTR chr4:166263783(+) A-I      3'UTR chr4:166263771(+) A-I      3'UTR chr4:166263792(+) A-I      3'UTR chr4:166263730(+) A-I      3'UTR chr4:166263706(+) A-I      3'UTR chr4:166263770(+) A-I      3'UTR chr4:166252350(+) A-I      intronic chr4:166251906(+) A-I      intronic chr4:166251862(+) A-I      intronic chr4:166251876(+) A-I      intronic chr4:166252201(+) A-I      intronic chr4:166251928(+) A-I      intronic chr4:166252327(+) A-I      intronic chr4:166252207(+) A-I      intronic chr4:166252315(+) A-I      intronic chr4:166250988(+) A-I      intronic chr4:166252306(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MSMO1	chr4:166250872(+) A-G intron -    22484847 chr4:166250887(+) A-G intron -    22484847 chr4:166252376(+) A-G intron -    22484847 chr4:166263517(+) T-A intron -    22484847 chr4:166263518(+) A-T intron -    22484847 chr4:166263519(+) T-A intron -    22484847 chr4:166263751(+) T-C intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MSMO1	chr4:166248862-166248863(+) m6A 5'UTR       24981863 chr4:166249070-166249071(+) m6A 5'UTR//intron       25456834//24981863 chr4:166249146-166249147(+) m6A 5'UTR//intron       24981863 chr4:166249196-166249197(+) m6A 5'UTR//intron       24981863 chr4:166261429-166261430(+) m6A CDS       24284625 chr4:166261510-166261511(+) m6A CDS       24284625//24209618//27773535//22608085 chr4:166261611-166261612(+) m6A 3'UTR//intron       24284625//24209618//27773535//22608085 chr4:166261761-166261762(+) m6A 3'UTR//intron       24284625//24981863 chr4:166262982-166262983(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr4:166262994-166262995(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr4:166263035-166263036(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr4:166263089-166263090(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr4:166263111-166263112(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr4:166263148-166263149(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22608085 chr4:166263217-166263218(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22608085 chr4:166263251-166263252(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22608085 chr4:166263339-166263340(+) m6A 3'UTR       27773535 chr4:166263410-166263411(+) m6A 3'UTR       27773535 chr4:166263531-166263532(+) m6A 3'UTR       27773535 chr4:166263821-166263822(+) m6A 3'UTR       27773535 chr4:166263865-166263866(+) m6A 3'UTR       27773535 chr4:166263928-166263929(+) m6A 3'UTR       26404942//27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3609	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)     -
	MSMO1	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3609
Interactor2: MSMO1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.