Basic Information:

  VIRBase ID:  

HHID00073021

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3609:  MIMAT0017986          LIF:  NM_001257135     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3609	LIF
miRBase Accession/Entrez ID	MIMAT0017986	3976
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CDF//DIA//HILDA//MLPLI

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3609	rs1201010739 chr7:98881721    C/A rs1379314154 chr7:98881711    G/T rs1433840969 chr7:98881723    G/A rs1360895354 chr7:98881703    A/C rs955400524 chr7:98881707    A/G rs955400524 chr7:98881707    A/T

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	LIF	chr22:30636813-30636814(-) m6A 3'UTR       24284625//27773535 chr22:30636949-30636950(-) m6A 3'UTR       24284625//24209618//24981863//27773535 chr22:30637024-30637025(-) m6A 3'UTR       24284625//24209618//24981863//27773535 chr22:30637080-30637081(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27371828 chr22:30637169-30637170(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr22:30637184-30637185(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr22:30637251-30637252(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr22:30637315-30637316(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr22:30637327-30637328(-) m6A 3'UTR       25456834//27371828//22575960 chr22:30637331-30637332(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr22:30637406-30637407(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr22:30637670-30637671(-) m6A 3'UTR       24209618 chr22:30637797-30637798(-) m6A 3'UTR       24209618//24981863 chr22:30637869-30637870(-) m6A 3'UTR       24284625//24209618//25456834//24981863 chr22:30637875-30637876(-) m6A 3'UTR       24284625//24209618//25456834//24981863 chr22:30637937-30637938(-) m6A 3'UTR       24284625//24209618//25456834//24981863 chr22:30637957-30637958(-) m6A 3'UTR       24284625//24209618//24981863 chr22:30637994-30637995(-) m6A 3'UTR       24284625//24209618//24981863 chr22:30638056-30638057(-) m6A 3'UTR       24284625//24209618 chr22:30638124-30638125(-) m6A 3'UTR       24284625 chr22:30638687-30638688(-) m6A 3'UTR       27773535 chr22:30638805-30638806(-) m6A 3'UTR       24209618//27773535 chr22:30638878-30638879(-) m6A 3'UTR       24209618 chr22:30638978-30638979(-) m6A 3'UTR       24209618//27371828 chr22:30639067-30639068(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942 chr22:30639081-30639082(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942 chr22:30639169-30639170(-) m6A 3'UTR       24284625//24209618//25456834//24981863 chr22:30639204-30639205(-) m6A 3'UTR       24284625//24209618//25456834//24981863 chr22:30639258-30639259(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27371828//22608085 chr22:30639280-30639281(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr22:30639325-30639326(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr22:30639375-30639376(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr22:30639394-30639395(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr22:30639448-30639449(-) m6A 3'UTR       24209618//25456834//24981863//27371828//22608085 chr22:30639516-30639517(-) m6A 3'UTR       24209618//25456834//24981863 chr22:30639539-30639540(-) m6A 3'UTR       24209618//25456834//24981863 chr22:30639613-30639614(-) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr22:30639883-30639884(-) m6A CDS       24284625//24209618//24981863//26404942//27371828//22575960//22608085 chr22:30639985-30639986(-) m6A CDS       24284625//24209618//24981863//26404942//27773535 chr22:30640012-30640013(-) m6A CDS       24284625//24209618//24981863//26404942//27773535 chr22:30640804-30640805(-) m6A CDS//intron       24284625//27773535 chr22:30640887-30640888(-) m6A CDS//intron       24284625 chr22:30642733-30642734(-) m6A 5'UTR       24284625 chr22:30642743-30642744(-) m6A 5'UTR       24284625 chr22:30642831-30642832(-) m6A 5'UTR       24209618

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3609	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)     -
	LIF	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3609
Interactor2: LIF

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.