Detail Information

Basic Information:


  VIRBase ID:  

HHID00073014

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3609:           GLRX:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3609 GLRX
miRBase
Accession/Entrez ID		 MIMAT0017986 2745
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - GRX//GRX1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3609
rs1201010739 chr7:98881721    C/A
rs1379314154 chr7:98881711    G/T
rs1433840969 chr7:98881723    G/A
rs1360895354 chr7:98881703    A/C
rs955400524 chr7:98881707    A/G
rs955400524 chr7:98881707    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR GLRX
chr5:95135488(-) A-I      intronic
chr5:95141825(-) A-I      intronic
chr5:95118331(-) A-I      ncRNA
chr5:95118510(-) A-I      ncRNA
chr5:95118382(-) A-I      ncRNA
chr5:95118323(-) A-I      ncRNA
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED GLRX
chr5:95153063(-) T-C intron -    22484847
chr5:95156285(-) A-C intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase GLRX
chr5:95149797-95149798(-) m6A 3'UTR//exon//intron       24284625//28052920
chr5:95149853-95149854(-) m6A 3'UTR//exon//intron       24981863
chr5:95149865-95149866(-) m6A 3'UTR//exon//intron       24981863
chr5:95149898-95149899(-) m6A 3'UTR//exon//intron       24981863
chr5:95149922-95149923(-) m6A 3'UTR//exon//intron       24981863
chr5:95149961-95149962(-) m6A 3'UTR//exon//intron       24981863
chr5:95154402-95154403(-) m6A exon//intron       27773535
chr5:95154516-95154517(-) m6A exon//intron       27773535
chr5:95158249-95158250(-) m6A CDS       24284625//27371828//22608085
chr5:95158346-95158347(-) m6A CDS       24284625//24981863//27371828//22608085
chr5:95158381-95158382(-) m6A 5'UTR       24284625//25456834//24981863//27371828//22608085
chr5:95158483-95158484(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3609
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)     -
GLRX
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Endoplasmic reticulum Human fibrosarcoma cells (HT1080)     25753659
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3609
Interactor2: GLRX

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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