Detail Information

Basic Information:


  VIRBase ID:  

HHID00072992

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3607-3p SLAIN1
miRBase
Accession/Entrez ID		 MIMAT0017985 122060
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C13orf32

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SLAIN1
chr13:78288585(+) A-I      intronic
chr13:78288589(+) A-I      intronic
chr13:78288582(+) A-I      intronic
chr13:78288558(+) A-I      intronic
chr13:78289103(+) A-I      intronic
chr13:78289212(+) A-I      intronic
chr13:78288636(+) A-I      intronic
chr13:78289190(+) A-I      intronic
chr13:78288587(+) A-I      intronic
chr13:78289142(+) A-I      intronic
chr13:78289083(+) A-I      intronic
chr13:78289104(+) A-I      intronic
chr13:78289203(+) A-I      intronic
chr13:78288641(+) A-I      intronic
chr13:78288568(+) A-I      intronic
chr13:78288588(+) A-I      intronic
chr13:78289183(+) A-I      intronic
chr13:78288625(+) A-I      intronic
chr13:78289144(+) A-I      intronic
chr13:78288565(+) A-I      intronic
chr13:78288668(+) A-I      intronic
chr13:78289192(+) A-I      intronic
chr13:78289132(+) A-I      intronic
chr13:78288513(+) A-I      intronic
chr13:78288563(+) A-I      intronic
chr13:78289248(+) A-I      intronic
chr13:78289186(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SLAIN1
chr13:78338016(+) A-I exon 3'UTR    19478186

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SLAIN1
chr13:78272138-78272139(+) m1A CDS//intron       26863410
chr13:78320691-78320692(+) m6A CDS//exon//intron       22608085
chr13:78320731-78320732(+) m6A CDS//exon//intron       22608085
chr13:78320857-78320858(+) m6A CDS//exon//intron       24981863//22608085
chr13:78320956-78320957(+) m6A CDS//intron       24981863//22608085
chr13:78320980-78320981(+) m6A CDS//intron       24981863//22608085
chr13:78334975-78334976(+) m6A CDS       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3607-3p
Exosome Plasma     23663360
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Microvesicle Fibroblasts|Mesenchymal stem cells     -
SLAIN1
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-3607-3p
Gemcitabine 60750 Drug interaction    RC00008306
5-Fluorouracil 3385 Drug interaction    RC00008305
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00008304
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719 Drug interaction    RC00008307
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-3607-3p
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719       26456124

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3607-3p
Interactor2: SLAIN1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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