Detail Information

Basic Information:


  VIRBase ID:  

HHID00072985

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3607-3p ADO
miRBase
Accession/Entrez ID		 MIMAT0017985 84890
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C10orf22

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ADO
chr10:64564760-64564761(+) m6A 5'UTR       24209618//25456834//27371828//27773536
chr10:64564829-64564830(+) m6A CDS       24284625//24209618//25456834//27371828//27773536
chr10:64564967-64564968(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr10:64565012-64565013(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr10:64565018-64565019(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr10:64565219-64565220(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr10:64565387-64565388(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr10:64565435-64565436(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr10:64565474-64565475(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr10:64565566-64565567(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr10:64565601-64565602(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr10:64565778-64565779(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr10:64565887-64565888(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085
chr10:64566425-64566426(+) m6A 3'UTR       24981863
chr10:64566852-64566853(+) m6A 3'UTR       26404942
chr10:64566864-64566865(+) m6A 3'UTR       26404942

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3607-3p
Exosome Plasma     23663360
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Microvesicle Fibroblasts|Mesenchymal stem cells     -
ADO
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-3607-3p
Gemcitabine 60750 Drug interaction    RC00008306
5-Fluorouracil 3385 Drug interaction    RC00008305
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00008304
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719 Drug interaction    RC00008307
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-3607-3p
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719       26456124

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3607-3p
Interactor2: ADO

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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