Detail Information

Basic Information:


  VIRBase ID:  

HHID00072965

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3607-3p KLHL9
miRBase
Accession/Entrez ID		 MIMAT0017985 55958
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR KLHL9
chr9:21330918(-) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase KLHL9
chr9:21331375-21331376(-) m6A 3'UTR       24284625//24981863//26404942//22608085
chr9:21331410-21331411(-) m6A 3'UTR       24284625//24981863//26404942//22608085
chr9:21331418-21331419(-) m6A 3'UTR       24284625//24981863//26404942//22608085
chr9:21331452-21331453(-) m6A 3'UTR       24284625//24981863//26404942//22608085
chr9:21331627-21331628(-) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr9:21331650-21331651(-) m6A 3'UTR       24284625//24981863//28052920//26404942//27773535//22608085
chr9:21331726-21331727(-) m6A 3'UTR       24284625//24981863//28052920//27773535//22608085
chr9:21331770-21331771(-) m6A 3'UTR       24284625//24981863//22608085
chr9:21331775-21331776(-) m6A 3'UTR       24284625//24981863//22608085
chr9:21333059-21333060(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr9:21333282-21333283(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr9:21333342-21333343(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr9:21333534-21333535(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr9:21333556-21333557(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr9:21333622-21333623(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr9:21333661-21333662(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr9:21333768-21333769(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr9:21333818-21333819(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr9:21333987-21333988(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085
chr9:21334074-21334075(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr9:21334092-21334093(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr9:21334178-21334179(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr9:21334216-21334217(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr9:21334222-21334223(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr9:21334282-21334283(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr9:21334319-21334320(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr9:21334487-21334488(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr9:21334499-21334500(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr9:21334516-21334517(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr9:21334562-21334563(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr9:21334597-21334598(-) m6A CDS       24284625//24209618//24981863//26404942//22608085
chr9:21334791-21334792(-) m6A CDS       24284625//22608085
chr9:21334917-21334918(-) m6A 5'UTR       24284625//25456834//24981863//22575960//22608085
chr9:21334936-21334937(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr9:21335118-21335119(-) m6A 5'UTR       24284625//25456834//24981863//27773536//22575960//22608085
chr9:21335156-21335157(-) m6A 5'UTR       24284625//24981863//27773536//22575960//22608085
chr9:21335221-21335222(-) m6A 5'UTR       27773536//22575960//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3607-3p
Exosome Plasma     23663360
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Microvesicle Fibroblasts|Mesenchymal stem cells     -
KLHL9
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-3607-3p
Gemcitabine 60750 Drug interaction    RC00008306
5-Fluorouracil 3385 Drug interaction    RC00008305
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00008304
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719 Drug interaction    RC00008307
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-3607-3p
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719       26456124

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3607-3p
Interactor2: KLHL9

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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