Basic Information:

  VIRBase ID:  

HHID00072840

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3200-5p:  MIMAT0017392          RACK1:  NM_006098     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3200-5p	RACK1
miRBase Accession/Entrez ID	MIMAT0017392	10399
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	Gnb2-rs1//GNB2L1//H12.3//HLC-7//PIG21

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3200-5p	rs1011470740 chr22:30731589    G/A rs1053414636 chr22:30731580    G/T rs1166967029 chr22:30731587    A/G rs1365077870 chr22:30731585    C/A rs1379215136 chr22:30731586    A/G rs891727946 chr22:30731581    C/T rs931335163 chr22:30731582    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RACK1	chr5:180667784(-) A-I      intronic chr5:180669832(-) A-I      intronic chr5:180669779(-) A-I      intronic chr5:180669815(-) A-I      intronic chr5:180667722(-) A-I      intronic chr5:180669620(-) A-I      intronic chr5:180669634(-) A-I      intronic chr5:180669664(-) A-I      intronic chr5:180669715(-) A-I      intronic chr5:180669736(-) A-I      intronic chr5:180669763(-) A-I      intronic chr5:180667957(-) A-I      ncRNA chr5:180669695(-) A-I      intronic chr5:180667912(-) A-I      intronic chr5:180667894(-) A-I      intronic chr5:180667778(-) A-I      intronic chr5:180669834(-) A-I      intronic chr5:180667800(-) A-I      intronic chr5:180669666(-) A-I      intronic chr5:180667733(-) A-I      intronic chr5:180667404(-) A-I      intronic chr5:180669786(-) A-I      intronic chr5:180669772(-) A-I      intronic chr5:180667966(-) A-I      ncRNA chr5:180667961(-) A-I      ncRNA chr5:180668002(-) A-I      ncRNA chr5:180668041(-) A-I      ncRNA

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3200-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	RACK1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Exosome Blood     - Membrane K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3200-5p
Interactor2: RACK1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.