Basic Information:

  VIRBase ID:  

HHID00072667

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3179:  MIMAT0015056          MICU3:  NM_001349810     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3179	MICU3
miRBase Accession/Entrez ID	MIMAT0015056	286097
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	EFHA2

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3179	rs1229893475 chr16:14901579    G/A rs1340262765 chr16:14901578    C/T rs1351100204 chr16:14901559    A/G rs1555527332 chr16:16300220    A/T rs1398613616 chr16:14901562    A/G rs1555527331 chr16:16300216    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MICU3	chr8:16886917(+) A-I      intronic chr8:16931669(+) A-I      intronic chr8:16896230(+) A-I      intronic chr8:16888928(+) A-I      intronic chr8:16889033(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MICU3	chr8:16977807-16977808(+) m6A 3'UTR       24981863 chr8:16977942-16977943(+) m6A 3'UTR       24981863 chr8:16977955-16977956(+) m6A 3'UTR       24981863 chr8:16977962-16977963(+) m6A 3'UTR       24981863 chr8:16978036-16978037(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3179	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	MICU3	Cytosol HCC cell line (HepG2)     - Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3179
Interactor2: MICU3

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.