Basic Information:

  VIRBase ID:  

HHID00072660

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3179:  MIMAT0015056          KNSTRN:  NM_033286     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3179	KNSTRN
miRBase Accession/Entrez ID	MIMAT0015056	90417
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	C15orf23//HSD11//SKAP//TRAF4AF1

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3179	rs1229893475 chr16:14901579    G/A rs1340262765 chr16:14901578    C/T rs1351100204 chr16:14901559    A/G rs1555527332 chr16:16300220    A/T rs1398613616 chr16:14901562    A/G rs1555527331 chr16:16300216    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	KNSTRN	chr15:40680044(+) A-I      intronic chr15:40680733(+) A-I      intronic chr15:40680056(+) A-I      intronic chr15:40680049(+) A-I      intronic chr15:40680057(+) A-I      intronic chr15:40680088(+) A-I      intronic chr15:40680089(+) A-I      intronic chr15:40680094(+) A-I      intronic chr15:40681430(+) A-I      intronic chr15:40680742(+) A-I      intronic chr15:40680102(+) A-I      intronic chr15:40680038(+) A-I      intronic chr15:40684725(+) A-I      intronic chr15:40681626(+) A-I      intronic chr15:40680066(+) A-I      intronic chr15:40684953(+) A-I      intronic chr15:40681515(+) A-I      intronic chr15:40680150(+) A-I      intronic chr15:40681413(+) A-I      intronic chr15:40681414(+) A-I      intronic chr15:40681632(+) A-I      intronic chr15:40684676(+) A-I      intronic chr15:40681476(+) A-I      intronic chr15:40681516(+) A-I      intronic chr15:40680775(+) A-I      intronic chr15:40680158(+) A-I      intronic chr15:40680053(+) A-I      intronic chr15:40679994(+) A-I      intronic chr15:40684719(+) A-I      intronic chr15:40680058(+) A-I      intronic chr15:40680164(+) A-I      intronic chr15:40685074(+) A-I      intronic chr15:40680115(+) A-I      intronic chr15:40680711(+) A-I      intronic chr15:40684938(+) A-I      intronic chr15:40681505(+) A-I      intronic chr15:40679999(+) A-I      intronic chr15:40681477(+) A-I      intronic chr15:40684929(+) A-I      intronic chr15:40681427(+) A-I      intronic chr15:40681512(+) A-I      intronic chr15:40680062(+) A-I      intronic chr15:40681540(+) A-I      intronic chr15:40680647(+) A-I      intronic chr15:40684912(+) A-I      intronic chr15:40681614(+) A-I      intronic chr15:40681475(+) A-I      intronic chr15:40684795(+) A-I      intronic chr15:40680070(+) A-I      intronic chr15:40681489(+) A-I      intronic chr15:40684937(+) A-I      intronic chr15:40681586(+) A-I      intronic chr15:40680141(+) A-I      intronic chr15:40680124(+) A-I      intronic chr15:40680757(+) A-I      intronic chr15:40684750(+) A-I      intronic chr15:40679947(+) A-I      intronic chr15:40684803(+) A-I      intronic chr15:40679976(+) A-I      intronic chr15:40681604(+) A-I      intronic chr15:40679975(+) A-I      intronic chr15:40682532(+) A-I      intronic chr15:40679960(+) A-I      intronic chr15:40681419(+) A-I      intronic chr15:40684786(+) A-I      intronic chr15:40680749(+) A-I      intronic chr15:40680745(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	KNSTRN	chr15:40675147-40675148(+) m6A 5'UTR//CDS//exon       24981863 chr15:40675217-40675218(+) m6A 5'UTR//CDS//exon       24284625//24981863 chr15:40675229-40675230(+) m6A 5'UTR//CDS//exon       24284625//24981863 chr15:40675471-40675472(+) m6A CDS//exon       24284625//24981863 chr15:40678994-40678995(+) m6A exon//intron       - chr15:40681712-40681713(+) m6A 3'UTR//CDS       - chr15:40681750-40681751(+) m6A 3'UTR//CDS       - chr15:40681756-40681757(+) m6A 3'UTR//CDS       - chr15:40681806-40681807(+) m6A 3'UTR//CDS       - chr15:40682049-40682050(+) m6A 3'UTR//CDS//exon       22575960 chr15:40684194-40684195(+) m6A 3'UTR//CDS//exon       27773535 chr15:40685719-40685720(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22608085 chr15:40685726-40685727(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22608085 chr15:40685834-40685835(+) Y 3'UTR       26075521 chr15:40685860-40685861(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr15:40685887-40685888(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr15:40685909-40685910(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr15:40685925-40685926(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr15:40685933-40685934(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr15:40686110-40686111(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr15:40686115-40686116(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr15:40686202-40686203(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr15:40686241-40686242(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr15:40686294-40686295(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr15:40686368-40686369(+) m6A 3'UTR       24284625//24981863//27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3179	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	KNSTRN	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3179
Interactor2: KNSTRN

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.