Basic Information:

  VIRBase ID:  

HHID00072655

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3179:  MIMAT0015056          PRR3:  NM_025263     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3179	PRR3
miRBase Accession/Entrez ID	MIMAT0015056	80742
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CAT56

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3179	rs1229893475 chr16:14901579    G/A rs1340262765 chr16:14901578    C/T rs1351100204 chr16:14901559    A/G rs1555527332 chr16:16300220    A/T rs1398613616 chr16:14901562    A/G rs1555527331 chr16:16300216    G/A

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PRR3	chr6:30524674-30524675(+) m6A 5'UTR       - chr6:30524680-30524681(+) m6A 5'UTR       - chr6:30524743-30524744(+) m6A 5'UTR       24284625//24981863//22608085 chr6:30525054-30525055(+) m6A 5'UTR       24284625//25456834//24981863//22608085 chr6:30525116-30525117(+) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//27371828//22608085 chr6:30525196-30525197(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27371828//22608085 chr6:30525969-30525970(+) m6A CDS//exon//intron       24284625//25456834//24981863//22608085 chr6:30529110-30529111(+) m6A exon//intron       24284625 chr6:30529180-30529181(+) m6A exon//intron       24284625//24209618//24981863//22608085 chr6:30529205-30529206(+) m6A exon//intron       24284625//24209618//24981863//27773535//22608085 chr6:30529240-30529241(+) m6A exon//intron       24284625//24209618//24981863//27773535//22608085 chr6:30529266-30529267(+) m6A exon//intron       24284625//24209618//24981863//27773535//22608085 chr6:30529282-30529283(+) m6A exon//intron       24284625//24209618//24981863//27773535//22608085 chr6:30529314-30529315(+) m6A exon//intron       24284625//24209618//24981863//27773535//22608085 chr6:30529324-30529325(+) m6A exon//intron       24284625//24981863//22608085 chr6:30529641-30529642(+) m6A CDS//exon       24284625 chr6:30529761-30529762(+) m6A CDS//exon       24284625 chr6:30529818-30529819(+) m6A CDS//exon       24284625 chr6:30529826-30529827(+) m6A CDS//exon       24284625 chr6:30530225-30530226(+) m6A CDS//exon       24284625//24209618//24981863//22575960//22608085 chr6:30530259-30530260(+) m6A CDS//exon       24284625//24209618//24981863//22575960//22608085 chr6:30530273-30530274(+) m6A 3'UTR//exon       24284625//24209618//24981863//22575960//22608085 chr6:30530486-30530487(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr6:30530499-30530500(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr6:30530563-30530564(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr6:30530570-30530571(+) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr6:30530737-30530738(+) m6A 3'UTR//exon       24284625//27773535 chr6:30530894-30530895(+) m6A 3'UTR//exon       24284625//24209618//27773535//22608085 chr6:30531003-30531004(+) m6A 3'UTR//exon       24284625//24209618//24981863//22608085 chr6:30531036-30531037(+) m6A 3'UTR//exon       24284625//24209618//24981863//22608085 chr6:30531048-30531049(+) m6A 3'UTR//exon       24284625//24209618//24981863//22608085 chr6:30531105-30531106(+) m6A 3'UTR//exon       24284625//24209618//24981863//22608085 chr6:30531177-30531178(+) m6A 3'UTR//exon       24284625//27773535 chr6:30531257-30531258(+) m6A 3'UTR//exon       24284625//27773535 chr6:30531323-30531324(+) m6A 3'UTR//exon       27773535 chr6:30531333-30531334(+) m6A 3'UTR//exon       27773535 chr6:30531349-30531350(+) m6A 3'UTR//exon       27773535 chr6:30531414-30531415(+) m6A 3'UTR//exon       24981863 chr6:30531483-30531484(+) m6A 3'UTR//exon       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3179	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	PRR3	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3179
Interactor2: PRR3

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.