Basic Information:

  VIRBase ID:  

HHID00072654

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3179:  MIMAT0015056          RNF34:  NM_194271     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3179	RNF34
miRBase Accession/Entrez ID	MIMAT0015056	80196
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CARP-1//CARP1//hRFI//RFI//RIF//RIFF

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3179	rs1229893475 chr16:14901579    G/A rs1340262765 chr16:14901578    C/T rs1351100204 chr16:14901559    A/G rs1555527332 chr16:16300220    A/T rs1398613616 chr16:14901562    A/G rs1555527331 chr16:16300216    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RNF34	chr12:121841993(+) A-I      intronic chr12:121842394(+) A-I      intronic chr12:121848261(+) A-I      intronic chr12:121850320(+) A-I      intronic chr12:121848164(+) A-I      intronic chr12:121848978(+) A-I      intronic chr12:121846966(+) A-I      intronic chr12:121850322(+) A-I      intronic chr12:121852553(+) A-I      intronic chr12:121848934(+) A-I      intronic chr12:121848873(+) A-I      intronic chr12:121848156(+) A-I      intronic chr12:121852742(+) A-I      intronic chr12:121846160(+) A-I      intronic chr12:121848866(+) A-I      intronic chr12:121846882(+) A-I      intronic chr12:121846963(+) A-I      intronic chr12:121852779(+) A-I      intronic chr12:121848130(+) A-I      intronic chr12:121848113(+) A-I      intronic chr12:121848815(+) A-I      intronic chr12:121848092(+) A-I      intronic chr12:121846043(+) A-I      intronic chr12:121850155(+) A-I      intronic chr12:121847837(+) A-I      intronic chr12:121846876(+) A-I      intronic chr12:121847827(+) A-I      intronic chr12:121848812(+) A-I      intronic chr12:121847819(+) A-I      intronic chr12:121845894(+) A-I      intronic chr12:121846019(+) A-I      intronic chr12:121847811(+) A-I      intronic chr12:121847798(+) A-I      intronic chr12:121847794(+) A-I      intronic chr12:121848807(+) A-I      intronic chr12:121846084(+) A-I      intronic chr12:121846948(+) A-I      intronic chr12:121848272(+) A-I      intronic chr12:121845994(+) A-I      intronic chr12:121846224(+) A-I      intronic chr12:121850314(+) A-I      intronic chr12:121848252(+) A-I      intronic chr12:121846079(+) A-I      intronic chr12:121848220(+) A-I      intronic chr12:121847005(+) A-I      intronic chr12:121846177(+) A-I      intronic chr12:121848193(+) A-I      intronic chr12:121846900(+) A-I      intronic chr12:121842329(+) A-I      intronic chr12:121848189(+) A-I      intronic chr12:121850123(+) A-I      intronic chr12:121846883(+) A-I      intronic chr12:121845989(+) A-I      intronic chr12:121849005(+) A-I      intronic chr12:121847004(+) A-I      intronic chr12:121848175(+) A-I      intronic chr12:121846980(+) A-I      intronic chr12:121848993(+) A-I      intronic chr12:121845877(+) A-I      intronic chr12:121844350(+) A-I      intronic chr12:121844329(+) A-I      intronic chr12:121844256(+) A-I      intronic chr12:121844226(+) A-I      intronic chr12:121844216(+) A-I      intronic chr12:121844207(+) A-I      intronic chr12:121843798(+) A-I      intronic chr12:121843778(+) A-I      intronic chr12:121843739(+) A-I      intronic chr12:121843738(+) A-I      intronic chr12:121843736(+) A-I      intronic chr12:121843726(+) A-I      intronic chr12:121843701(+) A-I      intronic chr12:121843690(+) A-I      intronic chr12:121843561(+) A-I      intronic chr12:121843549(+) A-I      intronic chr12:121843452(+) A-I      intronic chr12:121843416(+) A-I      intronic chr12:121843387(+) A-I      intronic chr12:121842448(+) A-I      intronic chr12:121842319(+) A-I      intronic chr12:121842262(+) A-I      intronic chr12:121841149(+) A-I      intronic chr12:121841144(+) A-I      intronic chr12:121841120(+) A-I      intronic chr12:121841105(+) A-I      intronic chr12:121841084(+) A-I      intronic chr12:121841078(+) A-I      intronic chr12:121841022(+) A-I      intronic chr12:121841020(+) A-I      intronic chr12:121841016(+) A-I      intronic chr12:121841012(+) A-I      intronic chr12:121840021(+) A-I      intronic chr12:121839972(+) A-I      intronic chr12:121856780(+) A-I      intronic chr12:121856629(+) A-I      intronic chr12:121856604(+) A-I      intronic chr12:121856555(+) A-I      intronic chr12:121853340(+) A-I      intronic chr12:121853339(+) A-I      intronic chr12:121846124(+) A-I      intronic chr12:121850172(+) A-I      intronic chr12:121853304(+) A-I      intronic chr12:121853277(+) A-I      intronic chr12:121853269(+) A-I      intronic chr12:121853265(+) A-I      intronic chr12:121853262(+) A-I      intronic chr12:121853240(+) A-I      intronic chr12:121853182(+) A-I      intronic chr12:121853162(+) A-I      intronic chr12:121853152(+) A-I      intronic chr12:121852805(+) A-I      intronic chr12:121842259(+) A-I      intronic chr12:121845840(+) A-I      intronic chr12:121853278(+) A-I      intronic chr12:121848243(+) A-I      intronic chr12:121847838(+) A-I      intronic chr12:121844160(+) A-I      intronic chr12:121853195(+) A-I      intronic chr12:121852736(+) A-I      intronic chr12:121848876(+) A-I      intronic chr12:121846125(+) A-I      intronic chr12:121853344(+) A-I      intronic chr12:121844114(+) A-I      intronic chr12:121847697(+) A-I      intronic chr12:121848219(+) A-I      intronic chr12:121848122(+) A-I      intronic chr12:121844155(+) A-I      intronic chr12:121856694(+) A-I      intronic chr12:121850182(+) A-I      intronic chr12:121846114(+) A-I      intronic chr12:121856572(+) A-I      intronic chr12:121847948(+) A-I      intronic chr12:121841088(+) A-I      intronic chr12:121844358(+) A-I      intronic chr12:121842009(+) A-I      intronic chr12:121853298(+) A-I      intronic chr12:121844190(+) A-I      intronic chr12:121848923(+) A-I      intronic chr12:121842403(+) A-I      intronic chr12:121841947(+) A-I      intronic chr12:121851092(+) A-I      intronic chr12:121845880(+) A-I      intronic chr12:121847889(+) A-I      intronic chr12:121848154(+) A-I      intronic chr12:121842078(+) A-I      intronic chr12:121848838(+) A-I      intronic chr12:121848087(+) A-I      intronic chr12:121856625(+) A-I      intronic chr12:121842267(+) A-I      intronic chr12:121853169(+) A-I      intronic chr12:121841845(+) A-I      intronic chr12:121845859(+) A-I      intronic chr12:121853299(+) A-I      intronic chr12:121844208(+) A-I      intronic chr12:121841879(+) A-I      intronic chr12:121841850(+) A-I      intronic chr12:121848777(+) A-I      intronic chr12:121845832(+) A-I      intronic chr12:121844146(+) A-I      intronic chr12:121852737(+) A-I      intronic chr12:121848831(+) A-I      intronic chr12:121846884(+) A-I      intronic chr12:121848917(+) A-I      intronic chr12:121840950(+) A-I      intronic chr12:121848086(+) A-I      intronic chr12:121843380(+) A-I      intronic chr12:121845853(+) A-I      intronic chr12:121843803(+) A-I      intronic chr12:121848769(+) A-I      intronic chr12:121847003(+) A-I      intronic chr12:121848878(+) A-I      intronic chr12:121846912(+) A-I      intronic chr12:121844229(+) A-I      intronic chr12:121843426(+) A-I      intronic chr12:121853273(+) A-I      intronic chr12:121846794(+) A-I      intronic chr12:121842307(+) A-I      intronic chr12:121841887(+) A-I      intronic chr12:121848761(+) A-I      intronic chr12:121841990(+) A-I      intronic chr12:121856593(+) A-I      intronic chr12:121847947(+) A-I      intronic chr12:121848837(+) A-I      intronic chr12:121842010(+) A-I      intronic chr12:121844325(+) A-I      intronic chr12:121840944(+) A-I      intronic chr12:121845854(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RNF34	chr12:121840950(+) A-I intron -    22327324 chr12:121841887(+) A-I intron -    22327324 chr12:121845840(+) A-I intron -    22327324 chr12:121856522(+) A-I intron -    21960545

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RNF34	chr12:121840587-121840588(+) m6A 5'UTR//exon//intron       24284625//24209618//24981863 chr12:121840593-121840594(+) m6A 5'UTR//exon//intron       24284625//24209618//24981863 chr12:121842662-121842663(+) m6A 5'UTR//intron       24284625//24981863 chr12:121847508-121847509(+) m6A 5'UTR//intron       - chr12:121854018-121854019(+) m6A CDS//exon//intron       24209618 chr12:121854085-121854086(+) m6A CDS//exon//intron       - chr12:121855402-121855403(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22608085 chr12:121855445-121855446(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr12:121855505-121855506(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:121855536-121855537(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:121855559-121855560(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:121855591-121855592(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:121855625-121855626(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:121855682-121855683(+) m6A CDS//exon//intron       24284625//24209618//22608085 chr12:121855687-121855688(+) m6A CDS//exon//intron       24284625//24209618//22608085 chr12:121858069-121858070(+) m6A CDS//exon//intron       24209618//24981863 chr12:121858525-121858526(+) m6A CDS//exon//intron       24209618//24981863 chr12:121858542-121858543(+) m6A CDS//exon//intron       24209618//24981863 chr12:121858569-121858570(+) m6A CDS//exon//intron       24209618//24981863 chr12:121861380-121861381(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:121861399-121861400(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:121861413-121861414(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:121861446-121861447(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:121861484-121861485(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:121861509-121861510(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:121861537-121861538(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:121861572-121861573(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:121861620-121861621(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr12:121861681-121861682(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22608085 chr12:121861729-121861730(+) m6A 3'UTR//exon//intron       24284625//24981863 chr12:121861747-121861748(+) m6A 3'UTR//exon//intron       24284625//24981863 chr12:121867899-121867900(+) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr12:121867945-121867946(+) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr12:121867965-121867966(+) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr12:121868089-121868090(+) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr12:121868131-121868132(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr12:121868136-121868137(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr12:121868146-121868147(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr12:121868161-121868162(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr12:121868242-121868243(+) m6A CDS       24284625//24209618//22608085 chr12:121868336-121868337(+) m6A 3'UTR       24284625

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3179	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	RNF34	Chromatin K562 cells     - Cytosol K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3179
Interactor2: RNF34

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.