Basic Information:

  VIRBase ID:  

HHID00072649

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3179:  MIMAT0015056          SEMA4A:  NM_001193300     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3179	SEMA4A
miRBase Accession/Entrez ID	MIMAT0015056	64218
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CORD10//RP35//SEMAB//SEMB

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3179	rs1229893475 chr16:14901579    G/A rs1340262765 chr16:14901578    C/T rs1351100204 chr16:14901559    A/G rs1555527332 chr16:16300220    A/T rs1398613616 chr16:14901562    A/G rs1555527331 chr16:16300216    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SEMA4A	chr1:156135754(+) A-I      intronic chr1:156133462(+) A-I      intronic chr1:156133613(+) A-I      intronic chr1:156133650(+) A-I      intronic chr1:156133809(+) A-I      intronic chr1:156136847(+) A-I      intronic chr1:156134731(+) A-I      intronic chr1:156139695(+) A-I      intronic chr1:156136921(+) A-I      intronic chr1:156134766(+) A-I      intronic chr1:156134767(+) A-I      intronic chr1:156134860(+) A-I      intronic chr1:156140094(+) A-I      intronic chr1:156135746(+) A-I      intronic chr1:156139701(+) A-I      intronic chr1:156135762(+) A-I      intronic chr1:156139705(+) A-I      intronic chr1:156140653(+) A-I      intronic chr1:156135784(+) A-I      intronic chr1:156137170(+) A-I      intronic chr1:156136626(+) A-I      intronic chr1:156135791(+) A-I      intronic chr1:156135797(+) A-I      intronic chr1:156141421(+) A-I      intronic chr1:156135798(+) A-I      intronic chr1:156135837(+) A-I      intronic chr1:156137743(+) A-I      intronic chr1:156139761(+) A-I      intronic chr1:156135853(+) A-I      intronic chr1:156139304(+) A-I      intronic chr1:156135878(+) A-I      intronic chr1:156139859(+) A-I      intronic chr1:156136024(+) A-I      intronic chr1:156139888(+) A-I      intronic chr1:156139418(+) A-I      intronic chr1:156139639(+) A-I      intronic chr1:156136669(+) A-I      intronic chr1:156141837(+) A-I      intronic chr1:156136825(+) A-I      intronic chr1:156140069(+) A-I      intronic chr1:156136822(+) A-I      intronic chr1:156133251(+) A-I      intronic chr1:156133280(+) A-I      intronic chr1:156137196(+) A-I      intronic chr1:156145817(+) A-I      intronic chr1:156136599(+) A-I      intronic chr1:156145918(+) A-I      intronic chr1:156137160(+) A-I      intronic chr1:156139669(+) A-I      intronic chr1:156134648(+) A-I      intronic chr1:156145928(+) A-I      intronic chr1:156145950(+) A-I      intronic chr1:156136857(+) A-I      intronic chr1:156136792(+) A-I      intronic chr1:156136908(+) A-I      intronic chr1:156136442(+) A-I      intronic chr1:156139737(+) A-I      intronic chr1:156141509(+) A-I      intronic chr1:156133337(+) A-I      intronic chr1:156137098(+) A-I      intronic chr1:156137047(+) A-I      intronic chr1:156137129(+) A-I      intronic chr1:156136804(+) A-I      intronic chr1:156140667(+) A-I      intronic chr1:156136849(+) A-I      intronic chr1:156133264(+) A-I      intronic chr1:156121577(+) A-I      intronic chr1:156133382(+) A-I      intronic chr1:156121009(+) A-I      intronic chr1:156142026(+) A-I      intronic chr1:156139562(+) A-I      intronic chr1:156141497(+) A-I      intronic chr1:156139932(+) A-I      intronic chr1:156133393(+) A-I      intronic chr1:156139967(+) A-I      intronic chr1:156133649(+) A-I      intronic chr1:156128918(+) A-I      intronic chr1:156133352(+) A-I      intronic chr1:156145924(+) A-I      intronic chr1:156137187(+) A-I      intronic chr1:156133736(+) A-I      intronic chr1:156139696(+) A-I      intronic chr1:156136834(+) A-I      intronic chr1:156137116(+) A-I      intronic chr1:156127184(+) A-I      intronic chr1:156135775(+) A-I      intronic chr1:156133714(+) A-I      intronic chr1:156134775(+) A-I      intronic chr1:156139275(+) A-I      intronic chr1:156139745(+) A-I      intronic chr1:156133573(+) A-I      intronic chr1:156137121(+) A-I      intronic chr1:156135827(+) A-I      intronic chr1:156134772(+) A-I      intronic chr1:156137054(+) A-I      intronic chr1:156137134(+) A-I      intronic chr1:156145991(+) A-I      intronic chr1:156145873(+) A-I      intronic chr1:156135932(+) A-I      intronic chr1:156140662(+) A-I      intronic chr1:156121433(+) A-I      intronic chr1:156137184(+) A-I      intronic chr1:156137166(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SEMA4A	chr1:156137054(+) A-I intron -    22327324 chr1:156133264(+) A-G intron -    22484847 chr1:156133352(+) A-G intron -    22484847 chr1:156134772(+) A-G intron -    22484847 chr1:156134775(+) A-G intron -    22484847 chr1:156135716(+) G-T intron -    22484847 chr1:156135717(+) A-T intron -    22484847 chr1:156135775(+) A-G intron -    22484847 chr1:156136442(+) A-G intron -    22484847 chr1:156136804(+) A-G intron -    22484847 chr1:156136834(+) A-G intron -    22484847 chr1:156137054(+) A-G intron -    22484847 chr1:156137116(+) A-G intron -    22484847 chr1:156137184(+) A-G intron -    22484847 chr1:156137187(+) A-G intron -    22484847 chr1:156139562(+) A-G intron -    22484847 chr1:156139696(+) A-G intron -    22484847 chr1:156139745(+) A-G intron -    22484847 chr1:156140662(+) A-G intron -    22484847 chr1:156140667(+) A-G intron -    22484847 chr1:156141509(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SEMA4A	chr1:156124611-156124612(+) m6A exon//intron       25456834 chr1:156124617-156124618(+) m6A exon//intron       25456834 chr1:156124642-156124643(+) m6A exon//intron       25456834 chr1:156124666-156124667(+) m6A exon//intron       25456834 chr1:156124678-156124679(+) m6A exon//intron       25456834 chr1:156124727-156124728(+) m6A exon//intron       25456834 chr1:156132747-156132748(+) m6A CDS//exon       - chr1:156146423-156146424(+) m6A CDS//exon       25456834 chr1:156146432-156146433(+) m6A CDS//exon       25456834 chr1:156146437-156146438(+) m6A CDS//exon       25456834 chr1:156146457-156146458(+) m6A CDS       25456834 chr1:156146662-156146663(+) m6A CDS       - chr1:156146731-156146732(+) m6A CDS       25456834 chr1:156146788-156146789(+) m6A 3'UTR       25456834//22608085 chr1:156146884-156146885(+) m6A 3'UTR       25456834 chr1:156146976-156146977(+) m6A 3'UTR       25456834//22608085 chr1:156147029-156147030(+) m6A 3'UTR       25456834//22608085 chr1:156147055-156147056(+) m6A 3'UTR       25456834//22608085 chr1:156147092-156147093(+) m6A 3'UTR       24981863//22608085 chr1:156147103-156147104(+) m6A 3'UTR       24981863//22608085 chr1:156147120-156147121(+) m6A 3'UTR       24981863//22608085 chr1:156147130-156147131(+) m6A 3'UTR       24981863//22608085 chr1:156147146-156147147(+) m6A 3'UTR       24981863//22608085 chr1:156147161-156147162(+) m6A 3'UTR       24981863//22608085 chr1:156147168-156147169(+) m6A 3'UTR       24981863//22608085 chr1:156147176-156147177(+) m6A 3'UTR       24981863//22608085 chr1:156147207-156147208(+) m6A 3'UTR       24981863//22608085 chr1:156147233-156147234(+) m6A 3'UTR       24981863//22608085 chr1:156147368-156147369(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3179	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	SEMA4A	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3179
Interactor2: SEMA4A

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.