Basic Information:

  VIRBase ID:  

HHID00072645

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3179:  MIMAT0015056          TDP1:  NM_001008744     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3179	TDP1
miRBase Accession/Entrez ID	MIMAT0015056	55775
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3179	rs1229893475 chr16:14901579    G/A rs1340262765 chr16:14901578    C/T rs1351100204 chr16:14901559    A/G rs1555527332 chr16:16300220    A/T rs1398613616 chr16:14901562    A/G rs1555527331 chr16:16300216    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TDP1	chr14:90472749(+) A-I      intronic chr14:90497881(+) A-I      intronic chr14:90505062(+) A-I      intronic chr14:90497236(+) A-I      intronic chr14:90497235(+) A-I      intronic chr14:90497189(+) A-I      intronic chr14:90487370(+) A-I      intronic chr14:90487314(+) A-I      intronic chr14:90474104(+) A-I      intronic chr14:90497880(+) A-I      intronic chr14:90474030(+) A-I      intronic chr14:90473826(+) A-I      intronic chr14:90473700(+) A-I      intronic chr14:90473699(+) A-I      intronic chr14:90473020(+) A-I      intronic chr14:90443345(+) A-I      intronic chr14:90469110(+) A-I      intronic chr14:90469043(+) A-I      intronic chr14:90443918(+) A-I      intronic chr14:90443904(+) A-I      intronic chr14:90443876(+) A-I      intronic chr14:90443842(+) A-I      intronic chr14:90443807(+) A-I      intronic chr14:90443746(+) A-I      intronic chr14:90443741(+) A-I      intronic chr14:90443719(+) A-I      intronic chr14:90443698(+) A-I      intronic chr14:90443448(+) A-I      intronic chr14:90442468(+) A-I      intronic chr14:90443390(+) A-I      intronic chr14:90443351(+) A-I      intronic chr14:90443339(+) A-I      intronic chr14:90468994(+) A-I      intronic chr14:90443327(+) A-I      intronic chr14:90443303(+) A-I      intronic chr14:90443288(+) A-I      intronic chr14:90443278(+) A-I      intronic chr14:90443007(+) A-I      intronic chr14:90442936(+) A-I      intronic chr14:90500317(+) A-I      intronic chr14:90442682(+) A-I      intronic chr14:90442680(+) A-I      intronic chr14:90442519(+) A-I      intronic chr14:90500331(+) A-I      intronic chr14:90442696(+) A-I      intronic chr14:90468936(+) A-I      intronic chr14:90503377(+) A-I      intronic chr14:90443742(+) A-I      intronic chr14:90443722(+) A-I      intronic chr14:90443376(+) A-I      intronic chr14:90443745(+) A-I      intronic chr14:90443312(+) A-I      intronic chr14:90473799(+) A-I      intronic chr14:90497227(+) A-I      intronic chr14:90505097(+) A-I      intronic chr14:90504976(+) A-I      intronic chr14:90503266(+) A-I      intronic chr14:90487320(+) A-I      intronic chr14:90503260(+) A-I      intronic chr14:90503254(+) A-I      intronic chr14:90503253(+) A-I      intronic chr14:90503233(+) A-I      intronic chr14:90497946(+) A-I      intronic chr14:90497942(+) A-I      intronic chr14:90497824(+) A-I      intronic chr14:90503240(+) A-I      intronic chr14:90497781(+) A-I      intronic chr14:90497933(+) A-I      intronic chr14:90473695(+) A-I      intronic chr14:90497214(+) A-I      intronic chr14:90503177(+) A-I      intronic chr14:90497244(+) A-I      intronic chr14:90497378(+) A-I      intronic chr14:90443388(+) A-I      intronic chr14:90443362(+) A-I      intronic chr14:90443454(+) A-I      intronic chr14:90474120(+) A-I      intronic chr14:90497240(+) A-I      intronic chr14:90443248(+) A-I      intronic chr14:90497190(+) A-I      intronic chr14:90503433(+) A-I      intronic chr14:90497800(+) A-I      intronic chr14:90503293(+) A-I      intronic chr14:90497760(+) A-I      intronic chr14:90497872(+) A-I      intronic chr14:90479097(+) A-I      intronic chr14:90443299(+) A-I      intronic chr14:90469057(+) A-I      intronic chr14:90478726(+) A-I      intronic chr14:90473806(+) A-I      intronic chr14:90497958(+) A-I      intronic chr14:90443706(+) A-I      intronic chr14:90442982(+) A-I      intronic chr14:90487375(+) A-I      intronic chr14:90468967(+) A-I      intronic chr14:90443449(+) A-I      intronic chr14:90473677(+) A-I      intronic chr14:90472754(+) A-I      intronic chr14:90503231(+) A-I      intronic chr14:90473691(+) A-I      intronic chr14:90468952(+) A-I      intronic chr14:90443419(+) A-I      intronic chr14:90473921(+) A-I      intronic chr14:90443464(+) A-I      intronic chr14:90468959(+) A-I      intronic chr14:90442981(+) A-I      intronic chr14:90469012(+) A-I      intronic chr14:90505102(+) A-I      intronic chr14:90473920(+) A-I      intronic chr14:90469137(+) A-I      intronic chr14:90497921(+) A-I      intronic chr14:90437380(+) A-I      intronic chr14:90497289(+) A-I      intronic chr14:90442944(+) A-I      intronic chr14:90497886(+) A-I      intronic chr14:90443797(+) A-I      intronic chr14:90474024(+) A-I      intronic chr14:90473989(+) A-I      intronic chr14:90469106(+) A-I      intronic chr14:90443379(+) A-I      intronic chr14:90497351(+) A-I      intronic chr14:90474092(+) A-I      intronic chr14:90497210(+) A-I      intronic chr14:90443242(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	TDP1	chr14:90478726(+) A-G intron -    22484847 chr14:90479097(+) A-G intron -    22484847 chr14:90497190(+) A-G intron -    22484847 chr14:90497378(+) A-G intron -    22484847 chr14:90497958(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TDP1	chr14:90429488-90429489(+) m6A CDS//intron       - chr14:90429529-90429530(+) m6A CDS//intron       24981863 chr14:90429534-90429535(+) m6A CDS//intron       24284625//24981863 chr14:90429708-90429709(+) m6A 5'UTR//CDS//intron       24284625//25456834//24981863//22608085 chr14:90429801-90429802(+) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr14:90429836-90429837(+) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr14:90429896-90429897(+) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr14:90429915-90429916(+) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr14:90429924-90429925(+) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr14:90429942-90429943(+) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr14:90510868-90510869(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3179	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	TDP1	Chromatin K562 cells     - Cytosol K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3179
Interactor2: TDP1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.