Basic Information:

  VIRBase ID:  

HHID00072643

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3179:  MIMAT0015056          PEX26:  NM_017929     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3179	PEX26
miRBase Accession/Entrez ID	MIMAT0015056	55670
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	PBD7A//PBD7B//PEX26M1T//Pex26pM1T

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3179	rs1229893475 chr16:14901579    G/A rs1340262765 chr16:14901578    C/T rs1351100204 chr16:14901559    A/G rs1555527332 chr16:16300220    A/T rs1398613616 chr16:14901562    A/G rs1555527331 chr16:16300216    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PEX26	chr22:18571387(+) A-I      3'UTR chr22:18572707(+) A-I      3'UTR chr22:18571325(+) A-I      3'UTR chr22:18571451(+) A-I      3'UTR chr22:18571395(+) A-I      3'UTR chr22:18568949(+) A-I      intronic chr22:18568966(+) A-I      intronic chr22:18568986(+) A-I      intronic chr22:18569858(+) A-I      intronic chr22:18569967(+) A-I      intronic chr22:18568921(+) A-I      intronic chr22:18567208(+) A-I      intronic chr22:18567216(+) A-I      intronic chr22:18567575(+) A-I      intronic chr22:18567694(+) A-I      intronic chr22:18568820(+) A-I      intronic chr22:18568888(+) A-I      intronic chr22:18568899(+) A-I      intronic chr22:18568904(+) A-I      intronic chr22:18568911(+) A-I      intronic chr22:18571483(+) A-I      3'UTR chr22:18574228(+) A-I      3'UTR chr22:18574221(+) A-I      3'UTR chr22:18574192(+) A-I      3'UTR chr22:18571413(+) A-I      3'UTR chr22:18571393(+) A-I      3'UTR chr22:18572711(+) A-I      3'UTR chr22:18572715(+) A-I      3'UTR chr22:18572537(+) A-I      3'UTR chr22:18572542(+) A-I      3'UTR chr22:18572744(+) A-I      3'UTR chr22:18571427(+) A-I      3'UTR chr22:18574135(+) A-I      3'UTR chr22:18572548(+) A-I      3'UTR chr22:18572523(+) A-I      3'UTR chr22:18572567(+) A-I      3'UTR chr22:18572594(+) A-I      3'UTR chr22:18571492(+) A-I      3'UTR chr22:18572604(+) A-I      3'UTR chr22:18572691(+) A-I      3'UTR chr22:18572699(+) A-I      3'UTR chr22:18570592(+) A-I      intronic chr22:18567062(+) A-I      intronic chr22:18568944(+) A-I      intronic chr22:18570021(+) A-I      intronic chr22:18569865(+) A-I      intronic chr22:18569014(+) A-I      intronic chr22:18568802(+) A-I      intronic chr22:18568943(+) A-I      intronic chr22:18569066(+) A-I      intronic chr22:18569045(+) A-I      intronic chr22:18570535(+) A-I      intronic chr22:18572633(+) A-I      3'UTR chr22:18572728(+) A-I      3'UTR chr22:18571457(+) A-I      3'UTR chr22:18571444(+) A-I      3'UTR chr22:18574212(+) A-I      3'UTR chr22:18572729(+) A-I      3'UTR chr22:18574144(+) A-I      3'UTR chr22:18571345(+) A-I      3'UTR chr22:18572742(+) A-I      3'UTR chr22:18571431(+) A-I      3'UTR chr22:18571344(+) A-I      3'UTR chr22:18572572(+) A-I      3'UTR chr22:18574149(+) A-I      3'UTR chr22:18573908(+) A-I      3'UTR chr22:18574189(+) A-I      3'UTR chr22:18571384(+) A-I      3'UTR chr22:18574222(+) A-I      3'UTR chr22:18571462(+) A-I      3'UTR chr22:18571386(+) A-I      3'UTR chr22:18571474(+) A-I      3'UTR chr22:18574165(+) A-I      3'UTR chr22:18571374(+) A-I      3'UTR chr22:18572751(+) A-I      3'UTR chr22:18572609(+) A-I      3'UTR chr22:18574166(+) A-I      3'UTR chr22:18571380(+) A-I      3'UTR chr22:18571398(+) A-I      3'UTR chr22:18571271(+) A-I      3'UTR chr22:18572650(+) A-I      3'UTR chr22:18571290(+) A-I      3'UTR chr22:18572675(+) A-I      3'UTR chr22:18571335(+) A-I      3'UTR chr22:18571385(+) A-I      3'UTR chr22:18571306(+) A-I      3'UTR chr22:18572719(+) A-I      3'UTR chr22:18572607(+) A-I      3'UTR chr22:18571359(+) A-I      3'UTR chr22:18571358(+) A-I      3'UTR chr22:18571392(+) A-I      3'UTR chr22:18572597(+) A-I      3'UTR chr22:18571402(+) A-I      3'UTR chr22:18572730(+) A-I      3'UTR chr22:18571438(+) A-I      3'UTR chr22:18571289(+) A-I      3'UTR chr22:18571298(+) A-I      3'UTR chr22:18571448(+) A-I      3'UTR chr22:18571394(+) A-I      3'UTR chr22:18572585(+) A-I      3'UTR chr22:18571383(+) A-I      3'UTR chr22:18571475(+) A-I      3'UTR chr22:18571476(+) A-I      3'UTR chr22:18574143(+) A-I      3'UTR chr22:18571312(+) A-I      3'UTR chr22:18572653(+) A-I      3'UTR chr22:18568917(+) A-I      intronic chr22:18568588(+) A-I      intronic chr22:18568420(+) A-I      intronic chr22:18569015(+) A-I      intronic chr22:18569772(+) A-I      intronic chr22:18568456(+) A-I      intronic chr22:18569867(+) A-I      intronic chr22:18568990(+) A-I      intronic chr22:18570024(+) A-I      intronic chr22:18568501(+) A-I      intronic chr22:18567150(+) A-I      intronic chr22:18568419(+) A-I      intronic chr22:18568831(+) A-I      intronic chr22:18568449(+) A-I      intronic chr22:18567550(+) A-I      intronic chr22:18567582(+) A-I      intronic chr22:18569820(+) A-I      intronic chr22:18563176(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PEX26	chr22:18571201(+) A-I exon 3'UTR    15342557 chr22:18571277(+) A-I exon 3'UTR    15342557 chr22:18571289(+) A-I exon 3'UTR    15342557 chr22:18571290(+) A-I exon 3'UTR    15342557 chr22:18572892(+) A-I exon 3'UTR    15342557 chr22:18571368(+) A-I intron -    22327324 chr22:18571369(+) A-I intron -    22327324 chr22:18571419(+) A-I intron -    21960545   //22327324 chr22:18571421(+) A-I intron -    21960545   //22327324 chr22:18571431(+) A-I intron -    21960545   //22327324 chr22:18571474(+) A-I intron -    22327324 chr22:18571477(+) A-I intron -    22327324 chr22:18572675(+) A-I intron -    21960545   //22327324 chr22:18572730(+) A-I intron -    22327324 chr22:18571271(+) A-I intron -    21960545 chr22:18571343(+) A-I intron -    21960545 chr22:18571345(+) A-I intron -    21960545 chr22:18572653(+) A-I intron -    21960545 chr22:18567289(+) A-G intron -    22484847 chr22:18568456(+) A-G intron -    22484847 chr22:18569970(+) A-G intron -    22484847 chr22:18571277(+) A-G intron -    22484847 chr22:18571281(+) A-G intron -    22484847 chr22:18571338(+) A-G intron -    22484847 chr22:18571343(+) A-G intron -    22484847 chr22:18571345(+) A-G intron -    22484847 chr22:18571346(+) A-G intron -    22484847 chr22:18571367(+) A-G intron -    22484847 chr22:18571368(+) A-G intron -    22484847 chr22:18571369(+) A-G intron -    22484847 chr22:18571383(+) A-G intron -    22484847 chr22:18571385(+) A-G intron -    22484847 chr22:18571389(+) A-G intron -    22484847 chr22:18571390(+) C-A intron -    22484847 chr22:18571402(+) A-G intron -    22484847 chr22:18571421(+) A-G intron -    22484847 chr22:18571431(+) A-G intron -    22484847 chr22:18571453(+) A-G intron -    22484847 chr22:18571454(+) A-G intron -    22484847 chr22:18571457(+) A-G intron -    22484847 chr22:18571462(+) A-G intron -    22484847 chr22:18571474(+) A-G intron -    22484847 chr22:18571475(+) A-G intron -    22484847 chr22:18571477(+) A-G intron -    22484847 chr22:18572572(+) A-G intron -    22484847 chr22:18572585(+) A-G intron -    22484847 chr22:18572597(+) A-G intron -    22484847 chr22:18572633(+) A-G intron -    22484847 chr22:18572650(+) A-G intron -    22484847 chr22:18572653(+) A-G intron -    22484847 chr22:18572675(+) A-G intron -    22484847 chr22:18572728(+) A-G intron -    22484847 chr22:18572729(+) A-G intron -    22484847 chr22:18572730(+) A-G intron -    22484847 chr22:18572742(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PEX26	chr22:18560717-18560718(+) m6A 5'UTR       24981863 chr22:18560934-18560935(+) m6A 5'UTR//intron       24284625//25456834//24981863//22608085 chr22:18561042-18561043(+) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr22:18561116-18561117(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr22:18561129-18561130(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr22:18561135-18561136(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr22:18561192-18561193(+) m6A CDS       24284625//24209618//22575960 chr22:18561248-18561249(+) m6A CDS       24284625//24209618//22575960//22608085 chr22:18561290-18561291(+) m6A CDS       24284625//22608085 chr22:18561310-18561311(+) m6A CDS       24284625//22608085 chr22:18561360-18561361(+) m6A CDS       24284625//22608085 chr22:18566451-18566452(+) m6A CDS//intron       24284625 chr22:18566457-18566458(+) m6A CDS//intron       24284625 chr22:18566489-18566490(+) m6A CDS//intron       24284625 chr22:18567931-18567932(+) m6A CDS//intron       24284625 chr22:18570939-18570940(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr22:18571033-18571034(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr22:18571043-18571044(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr22:18571067-18571068(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr22:18571115-18571116(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr22:18571121-18571122(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr22:18571135-18571136(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr22:18571251-18571252(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr22:18571345-18571346(+) m6A 3'UTR//intron       24981863 chr22:18571368-18571369(+) m6A 3'UTR//intron       - chr22:18572086-18572087(+) m6A 3'UTR//intron       24981863 chr22:18572138-18572139(+) m6A 3'UTR//intron       24981863 chr22:18572160-18572161(+) m6A 3'UTR//intron       24981863 chr22:18572168-18572169(+) m6A 3'UTR//intron       - chr22:18572801-18572802(+) m6A 3'UTR//intron       - chr22:18573293-18573294(+) m6A 3'UTR//intron       24284625 chr22:18573570-18573571(+) m6A 3'UTR//intron       24981863 chr22:18573616-18573617(+) m6A 3'UTR//intron       24981863 chr22:18574772-18574773(+) m6A 3'UTR//intron       - chr22:18574801-18574802(+) m6A 3'UTR//intron       24284625//22575960 chr22:18574917-18574918(+) m6A 3'UTR//intron       24284625//25456834//24981863//22575960//22608085 chr22:18575044-18575045(+) m6A 3'UTR//intron       24284625//25456834//22608085 chr22:18575106-18575107(+) m6A 3'UTR//intron       24284625//25456834//22608085 chr22:18575140-18575141(+) m6A 3'UTR//intron       24284625//25456834//22608085 chr22:18575222-18575223(+) m6A 3'UTR//intron       25456834 chr22:18575255-18575256(+) m6A 3'UTR//intron       25456834 chr22:18575635-18575636(+) m6A 3'UTR//intron       27773535 chr22:18575646-18575647(+) m6A 3'UTR//intron       27773535 chr22:18583600-18583601(+) m6A 3'UTR//intron       - chr22:18583609-18583610(+) m6A 3'UTR//intron       - chr22:18583913-18583914(+) m6A 3'UTR//intron       - chr22:18583921-18583922(+) m6A 3'UTR//intron       - chr22:18583943-18583944(+) m6A 3'UTR//intron       - chr22:18583972-18583973(+) m6A 3'UTR//intron       - chr22:18584874-18584875(+) m6A 3'UTR//intron       24284625 chr22:18584883-18584884(+) m6A 3'UTR//intron       24284625 chr22:18609332-18609333(+) m6A 3'UTR       24284625//24981863//22575960//22608085 chr22:18609358-18609359(+) m6A 3'UTR       24284625//24981863//22575960//22608085 chr22:18609391-18609392(+) m6A 3'UTR       24284625//24981863//22575960//22608085 chr22:18609496-18609497(+) m6A 3'UTR       24284625//22608085 chr22:18609513-18609514(+) m6A 3'UTR       24284625//22608085 chr22:18609596-18609597(+) m6A 3'UTR       24284625 chr22:18609668-18609669(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3179	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	PEX26	Cytosol K562 cells     - Exosome Blood     - Insoluble cytoplasm K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3179
Interactor2: PEX26

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.