Detail Information

Basic Information:


  VIRBase ID:  

HHID00072626

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3179:           HSPH1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3179 HSPH1
miRBase
Accession/Entrez ID		 MIMAT0015056 10808
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - HSP105//HSP105A//HSP105B//NY-CO-25

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3179
rs1229893475 chr16:14901579    G/A
rs1340262765 chr16:14901578    C/T
rs1351100204 chr16:14901559    A/G
rs1555527332 chr16:16300220    A/T
rs1398613616 chr16:14901562    A/G
rs1555527331 chr16:16300216    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR HSPH1
chr13:31720050(-) A-I      intronic
chr13:31720086(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase HSPH1
chr13:31711376-31711377(-) m6A 3'UTR//exon//intron       24981863//26404942//27773535
chr13:31711458-31711459(-) m6A 3'UTR//CDS//exon//intron       24284625//24981863//26404942//27773535//27371828//22608085
chr13:31711464-31711465(-) m6A 3'UTR//CDS//exon//intron       24284625//24981863//26404942//27773535//27371828//22608085
chr13:31711520-31711521(-) m6A 3'UTR//CDS//exon       24284625//24981863//26404942//27773535//27371828//22608085
chr13:31711536-31711537(-) m6A 3'UTR//CDS//exon       24284625//24981863//26404942//27773535//27371828//22608085
chr13:31711542-31711543(-) m6A 3'UTR//CDS//exon       24284625//24981863//26404942//27773535//27371828//22608085
chr13:31711588-31711589(-) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//27371828//22608085
chr13:31711598-31711599(-) m6A 3'UTR//CDS//exon       24981863//27773535//22608085
chr13:31711619-31711620(-) m6A 3'UTR//CDS//exon       24981863//27773535//22608085
chr13:31711640-31711641(-) m6A 3'UTR//CDS//exon       24981863//27773535//22575960//22608085
chr13:31711653-31711654(-) m6A 3'UTR//CDS//exon       24981863//27773535//22575960//22608085
chr13:31712554-31712555(-) m6A 3'UTR//CDS//exon       24981863//27773535//22575960//22608085
chr13:31712947-31712948(-) Y 3'UTR//CDS//exon       26075521
chr13:31712965-31712966(-) m6A 3'UTR//CDS//exon       27773535
chr13:31712971-31712972(-) m6A 3'UTR//CDS//exon       27773535
chr13:31713169-31713170(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr13:31713179-31713180(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr13:31713191-31713192(-) Am 3'UTR//CDS//exon       -
chr13:31713203-31713204(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr13:31713210-31713211(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr13:31713223-31713224(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr13:31714347-31714348(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr13:31714360-31714361(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr13:31715263-31715264(-) m6A 3'UTR//CDS//exon       24981863//26404942//27773535//22575960
chr13:31715286-31715287(-) m6A 3'UTR//CDS//exon       24981863//26404942//27773535//22575960
chr13:31717950-31717951(-) m6A 3'UTR//CDS//exon//intron       24981863
chr13:31717967-31717968(-) m6A 3'UTR//CDS//exon//intron       24981863
chr13:31717993-31717994(-) m6A 3'UTR//CDS//exon//intron       24981863
chr13:31718008-31718009(-) m6A 3'UTR//CDS//exon//intron       24981863
chr13:31718026-31718027(-) m6A 3'UTR//CDS//exon//intron       24981863
chr13:31718043-31718044(-) m6A 3'UTR//CDS//exon//intron       24981863
chr13:31725143-31725144(-) m6A 3'UTR//CDS//exon       26404942
chr13:31725175-31725176(-) m6A 3'UTR//CDS//exon       26404942
chr13:31728793-31728794(-) m6A CDS//exon//intron       26404942//22575960
chr13:31728806-31728807(-) m6A CDS//exon//intron       26404942//22575960
chr13:31728816-31728817(-) m6A CDS//exon//intron       26404942//22575960
chr13:31728871-31728872(-) m6A CDS//exon//intron       26404942//22575960
chr13:31729699-31729700(-) m6A CDS//exon       26404942
chr13:31729774-31729775(-) m6A CDS//exon       24981863//26404942
chr13:31732968-31732969(-) m6A CDS//exon       24209618//24981863//27773535//27371828
chr13:31735646-31735647(-) m6A CDS//intron       24209618//24981863//27773535//27371828//27773536//22575960
chr13:31735732-31735733(-) m6A 5'UTR//intron       24209618//25456834//24981863//27371828//27773536//22575960
chr13:31735749-31735750(-) m6A 5'UTR//intron       24209618//25456834//24981863//27371828//27773536//22575960
chr13:31735755-31735756(-) m6A 5'UTR//intron       24209618//25456834//24981863//27371828//27773536//22575960
chr13:31735833-31735834(-) m6A 5'UTR//intron       24209618//25456834//24981863//27371828//27773536//22575960
chr13:31735932-31735933(-) Y 5'UTR//intron       26075521
chr13:31736052-31736053(-) m6A 5'UTR//intron       24284625//24209618//24981863//27371828
chr13:31736079-31736080(-) Y intron       26075521
chr13:31736160-31736161(-) m1A CDS//exon       26863196//26863410
chr13:31736204-31736205(-) m6A CDS       24981863
chr13:31736383-31736384(-) m6A 5'UTR       24981863
chr13:31736481-31736482(-) m6A 5'UTR       24981863
chr13:31736507-31736508(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3179
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
HSPH1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -
Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3179
Interactor2: HSPH1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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