Detail Information

Basic Information:


  VIRBase ID:  

HHID00072623

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3179:           NME6:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3179 NME6
miRBase
Accession/Entrez ID		 MIMAT0015056 10201
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - IPIA-ALPHA//NDK 6//NM23-H6

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3179
rs1229893475 chr16:14901579    G/A
rs1340262765 chr16:14901578    C/T
rs1351100204 chr16:14901559    A/G
rs1555527332 chr16:16300220    A/T
rs1398613616 chr16:14901562    A/G
rs1555527331 chr16:16300216    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR NME6
chr3:48337047(-) A-I      intronic
chr3:48337295(-) A-I      intronic
chr3:48342294(-) A-I      intronic
chr3:48342452(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED NME6
chr3:48342294(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase NME6
chr3:48334755-48334756(-) m6A 3'UTR       24981863//22608085
chr3:48334783-48334784(-) m6A 3'UTR       24981863//22608085
chr3:48334792-48334793(-) m6A 3'UTR       24981863//22608085
chr3:48334801-48334802(-) m6A 3'UTR       24981863//22608085
chr3:48334815-48334816(-) m6A 3'UTR       24981863//22608085
chr3:48334866-48334867(-) m6A 3'UTR       22608085
chr3:48335245-48335246(-) m6A 3'UTR       27773535
chr3:48335274-48335275(-) m6A 3'UTR       27773535
chr3:48335304-48335305(-) m6A 3'UTR       27773535
chr3:48335393-48335394(-) m6A 3'UTR       27773535//22608085
chr3:48335456-48335457(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr3:48335530-48335531(-) m6A 3'UTR       24284625//24981863//27773535//27371828//22608085
chr3:48335660-48335661(-) m6A 3'UTR//exon       24284625//25456834//24981863//27773535//27371828//22608085
chr3:48335756-48335757(-) m6A 3'UTR//exon       24284625//24981863//22608085
chr3:48335779-48335780(-) m6A 3'UTR//exon       24284625//24981863//22608085
chr3:48335893-48335894(-) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22608085
chr3:48336010-48336011(-) Y 3'UTR//exon       26075521
chr3:48336054-48336055(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr3:48336067-48336068(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr3:48336081-48336082(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr3:48336092-48336093(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr3:48336110-48336111(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr3:48336135-48336136(-) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr3:48336149-48336150(-) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr3:48336237-48336238(-) m6A 3'UTR//CDS//exon       24284625//27371828
chr3:48338256-48338257(-) Gm CDS//exon//intron       -
chr3:48339331-48339332(-) m6A exon//intron       25456834
chr3:48339393-48339394(-) m6A exon//intron       25456834
chr3:48339431-48339432(-) m6A exon//intron       25456834
chr3:48339475-48339476(-) m6A exon//intron       25456834
chr3:48341875-48341876(-) m6A 5'UTR//intron       27773535
chr3:48341884-48341885(-) m6A 5'UTR//intron       27773535
chr3:48342942-48342943(-) m6A 5'UTR       24981863
chr3:48342948-48342949(-) m6A 5'UTR       24981863
chr3:48343002-48343003(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3179
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
NME6
Chromatin K562 cells     -
Exosome Blood     -
Nucleus K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3179
Interactor2: NME6

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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