Basic Information:

  VIRBase ID:  

HHID00072607

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3179:  MIMAT0015056          DGKD:  NM_152879     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3179	DGKD
miRBase Accession/Entrez ID	MIMAT0015056	8527
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	DGK-delta//dgkd-2//DGKdelta

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3179	rs1229893475 chr16:14901579    G/A rs1340262765 chr16:14901578    C/T rs1351100204 chr16:14901559    A/G rs1555527332 chr16:16300220    A/T rs1398613616 chr16:14901562    A/G rs1555527331 chr16:16300216    G/A

RNA Editing:

Resource	Symbol	Editing Position
Lncediting	DGKD	chr2: 234300856     chr2: 234300873     chr2: 234300854

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	DGKD	chr2:234312510(+) A-I      intronic chr2:234270654(+) A-I      intronic chr2:234270678(+) A-I      intronic chr2:234312517(+) A-I      intronic chr2:234283757(+) A-I      intronic chr2:234286476(+) A-I      intronic chr2:234283816(+) A-I      intronic chr2:234270627(+) A-I      intronic chr2:234271132(+) A-I      intronic chr2:234336223(+) A-I      intronic chr2:234283826(+) A-I      intronic chr2:234283843(+) A-I      intronic chr2:234283857(+) A-I      intronic chr2:234283858(+) A-I      intronic chr2:234285846(+) A-I      intronic chr2:234285921(+) A-I      intronic chr2:234286507(+) A-I      intronic chr2:234310293(+) A-I      intronic chr2:234307538(+) A-I      intronic chr2:234302483(+) A-I      intronic chr2:234290867(+) A-I      intronic chr2:234290786(+) A-I      intronic chr2:234287504(+) A-I      intronic chr2:234287473(+) A-I      intronic chr2:234286526(+) A-I      intronic chr2:234286524(+) A-I      intronic chr2:234312366(+) A-I      intronic chr2:234269237(+) A-I      intronic chr2:234336231(+) A-I      intronic chr2:234312386(+) A-I      intronic chr2:234277052(+) A-I      intronic chr2:234312305(+) A-I      intronic chr2:234312041(+) A-I      intronic chr2:234283344(+) A-I      intronic chr2:234283414(+) A-I      intronic chr2:234270347(+) A-I      intronic chr2:234312403(+) A-I      intronic chr2:234312462(+) A-I      intronic chr2:234316315(+) A-I      intronic chr2:234316338(+) A-I      intronic chr2:234269255(+) A-I      intronic chr2:234270503(+) A-I      intronic chr2:234270541(+) A-I      intronic chr2:234270545(+) A-I      intronic chr2:234270575(+) A-I      intronic chr2:234270706(+) A-I      intronic chr2:234271095(+) A-I      intronic chr2:234271110(+) A-I      intronic chr2:234312020(+) A-I      intronic chr2:234312015(+) A-I      intronic chr2:234270519(+) A-I      intronic chr2:234312010(+) A-I      intronic chr2:234271135(+) A-I      intronic chr2:234271177(+) A-I      intronic chr2:234275992(+) A-I      intronic chr2:234276016(+) A-I      intronic chr2:234276084(+) A-I      intronic chr2:234276899(+) A-I      intronic chr2:234277047(+) A-I      intronic chr2:234270704(+) A-I      intronic chr2:234270338(+) A-I      intronic chr2:234271265(+) A-I      intronic chr2:234275968(+) A-I      intronic chr2:234275906(+) A-I      intronic chr2:234271226(+) A-I      intronic chr2:234310311(+) A-I      intronic chr2:234311935(+) A-I      intronic chr2:234287566(+) A-I      intronic chr2:234270635(+) A-I      intronic chr2:234287130(+) A-I      intronic chr2:234287131(+) A-I      intronic chr2:234311944(+) A-I      intronic chr2:234270641(+) A-I      intronic chr2:234314044(+) A-I      intronic chr2:234283839(+) A-I      intronic chr2:234312497(+) A-I      intronic chr2:234374214(+) A-I      intronic chr2:234282877(+) A-I      intronic chr2:234310360(+) A-I      intronic chr2:234270462(+) A-I      intronic chr2:234287536(+) A-I      intronic chr2:234307357(+) A-I      intronic chr2:234270472(+) A-I      intronic chr2:234287579(+) A-I      intronic chr2:234312548(+) A-I      intronic chr2:234283421(+) A-I      intronic chr2:234286951(+) A-I      intronic chr2:234303454(+) A-I      intronic chr2:234302562(+) A-I      intronic chr2:234312562(+) A-I      intronic chr2:234268996(+) A-I      intronic chr2:234287642(+) A-I      intronic chr2:234271242(+) A-I      intronic chr2:234271217(+) A-I      intronic chr2:234286911(+) A-I      intronic chr2:234270363(+) A-I      intronic chr2:234269124(+) A-I      intronic chr2:234270649(+) A-I      intronic chr2:234312415(+) A-I      intronic chr2:234312471(+) A-I      intronic chr2:234271176(+) A-I      intronic chr2:234312533(+) A-I      intronic chr2:234310390(+) A-I      intronic chr2:234271087(+) A-I      intronic chr2:234312148(+) A-I      intronic chr2:234323706(+) A-I      intronic chr2:234282836(+) A-I      intronic chr2:234277038(+) A-I      intronic chr2:234276977(+) A-I      intronic chr2:234266257(+) A-I      intronic chr2:234283808(+) A-I      intronic chr2:234283417(+) A-I      intronic chr2:234312389(+) A-I      intronic chr2:234310455(+) A-I      intronic chr2:234270339(+) A-I      intronic chr2:234312468(+) A-I      intronic chr2:234283774(+) A-I      intronic chr2:234310481(+) A-I      intronic chr2:234270666(+) A-I      intronic chr2:234279510(+) A-I      intronic chr2:234276072(+) A-I      intronic chr2:234286510(+) A-I      intronic chr2:234286688(+) A-I      intronic chr2:234283729(+) A-I      intronic chr2:234276014(+) A-I      intronic chr2:234286646(+) A-I      intronic chr2:234286501(+) A-I      intronic chr2:234283771(+) A-I      intronic chr2:234312485(+) A-I      intronic chr2:234271247(+) A-I      intronic chr2:234282838(+) A-I      intronic chr2:234291949(+) A-I      intronic chr2:234269270(+) A-I      intronic chr2:234291921(+) A-I      intronic chr2:234270625(+) A-I      intronic chr2:234316230(+) A-I      intronic chr2:234310364(+) A-I      intronic chr2:234283794(+) A-I      intronic chr2:234282959(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	DGKD	chr2:234316138(+) A-I intron -    21960545 chr2:234270624(+) A-G intron -    22484847 chr2:234270625(+) A-G intron -    22484847 chr2:234270635(+) A-G intron -    22484847 chr2:234270641(+) A-G intron -    22484847 chr2:234270649(+) A-G intron -    22484847 chr2:234271087(+) A-G intron -    22484847 chr2:234271138(+) A-G intron -    22484847 chr2:234275906(+) A-G intron -    22484847 chr2:234275968(+) A-G intron -    22484847 chr2:234276900(+) A-G intron -    22484847 chr2:234276977(+) A-G intron -    22484847 chr2:234283235(+) T-C intron -    22484847 chr2:234283421(+) A-G intron -    22484847 chr2:234283435(+) A-G intron -    22484847 chr2:234283729(+) A-G intron -    22484847 chr2:234283794(+) A-G intron -    22484847 chr2:234286937(+) A-G intron -    22484847 chr2:234286951(+) A-G intron -    22484847 chr2:234287566(+) A-G intron -    22484847 chr2:234287579(+) A-G intron -    22484847 chr2:234302241(+) T-C intron -    22484847 chr2:234311944(+) A-G intron -    22484847 chr2:234312148(+) A-G intron -    22484847 chr2:234312389(+) A-G intron -    22484847 chr2:234312390(+) A-G intron -    22484847 chr2:234312425(+) A-G intron -    22484847 chr2:234312468(+) A-G intron -    22484847 chr2:234312471(+) A-G intron -    22484847 chr2:234312485(+) A-G intron -    22484847 chr2:234312488(+) A-G intron -    22484847 chr2:234312497(+) A-G intron -    22484847 chr2:234312533(+) A-G intron -    22484847 chr2:234312548(+) A-G intron -    22484847 chr2:234316292(+) A-G intron -    22484847 chr2:234351315(+) G-A intron -    22484847 chr2:234351477(+) C-T intron -    22484847 chr2:234351493(+) G-T intron -    22484847 chr2:234351509(+) C-A intron -    22484847 chr2:234351518(+) G-T intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DGKD	chr2:234263962-234263963(+) Tm intron       - chr2:234294605-234294606(+) m6A CDS//intron       - chr2:234343109-234343110(+) Cm CDS//exon       - chr2:234363437-234363438(+) m6A 3'UTR//CDS//exon       26404942 chr2:234363479-234363480(+) m6A 3'UTR//CDS//exon       26404942 chr2:234365551-234365552(+) m6A 3'UTR//CDS//exon       26404942 chr2:234365558-234365559(+) m6A 3'UTR//CDS//exon       26404942 chr2:234365584-234365585(+) m6A 3'UTR//CDS//exon       26404942 chr2:234365605-234365606(+) m6A 3'UTR//CDS//exon       26404942 chr2:234365615-234365616(+) m6A 3'UTR//CDS//exon       26404942 chr2:234366261-234366262(+) m6A exon//intron       24284625 chr2:234366362-234366363(+) m6A exon//intron       24284625 chr2:234371345-234371346(+) Gm 3'UTR//CDS       - chr2:234378305-234378306(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22575960//22608085 chr2:234378330-234378331(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22575960//22608085 chr2:234378614-234378615(+) m6A 3'UTR       24284625//24981863 chr2:234379211-234379212(+) m6A 3'UTR       24284625 chr2:234380155-234380156(+) m6A 3'UTR       25456834//24981863 chr2:234380176-234380177(+) m6A 3'UTR       25456834//24981863 chr2:234380193-234380194(+) m6A 3'UTR       25456834//24981863 chr2:234380208-234380209(+) m6A 3'UTR       25456834//24981863 chr2:234380230-234380231(+) m6A 3'UTR       25456834//24981863 chr2:234380645-234380646(+) m6A 3'UTR       27773535 chr2:234380721-234380722(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3179	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	DGKD	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3179
Interactor2: DGKD

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.