Detail Information

Basic Information:


  VIRBase ID:  

HHID00072522

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3174:           PARP14:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3174 PARP14
miRBase
Accession/Entrez ID		 MIMAT0015051 54625
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ARTD8//BAL2//PARP-14//pART8

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3174
rs1159846130 chr15:90006777    A/G
rs1295514792 chr15:90006764    T/TGTTAGAGATGC
rs775051847 chr15:90006779    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PARP14
chr3:122441883(+) A-I      intronic
chr3:122441912(+) A-I      intronic
chr3:122441917(+) A-I      intronic
chr3:122441918(+) A-I      intronic
chr3:122441919(+) A-I      intronic
chr3:122441882(+) A-I      intronic
chr3:122413601(+) A-I      intronic
chr3:122413516(+) A-I      intronic
chr3:122412504(+) A-I      intronic
chr3:122412559(+) A-I      intronic
chr3:122413564(+) A-I      intronic
chr3:122421143(+) A-I      intronic
chr3:122413485(+) A-I      intronic
chr3:122443429(+) A-I      intronic
chr3:122431583(+) A-I      intronic
chr3:122431171(+) A-I      intronic
chr3:122426124(+) A-I      intronic
chr3:122412643(+) A-I      intronic
chr3:122412534(+) A-I      intronic
chr3:122421752(+) A-I      intronic
chr3:122412453(+) A-I      intronic
chr3:122421716(+) A-I      intronic
chr3:122412537(+) A-I      intronic
chr3:122426522(+) A-I      intronic
chr3:122412528(+) A-I      intronic
chr3:122412487(+) A-I      intronic
chr3:122431540(+) A-I      intronic
chr3:122413576(+) A-I      intronic
chr3:122412431(+) A-I      intronic
chr3:122404498(+) A-I      intronic
chr3:122421163(+) A-I      intronic
chr3:122426524(+) A-I      intronic
chr3:122443215(+) A-I      intronic
chr3:122413508(+) A-I      intronic
chr3:122421698(+) A-I      intronic
chr3:122412637(+) A-I      intronic
chr3:122401822(+) A-I      intronic
chr3:122401823(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED PARP14
chr3:122412487(+) A-G intron -    22484847
chr3:122413508(+) A-G intron -    22484847
chr3:122416060(+) T-C intron -    22484847
chr3:122421163(+) A-G intron -    22484847
chr3:122421164(+) A-G intron -    22484847
chr3:122421698(+) A-G intron -    22484847
chr3:122431103(+) C-T intron -    22484847
chr3:122431199(+) C-T intron -    22484847
chr3:122431365(+) A-G intron -    22484847
chr3:122440232(+) A-G intron -    22484847
chr3:122440276(+) C-A intron -    22484847
chr3:122440334(+) T-C intron -    22484847
chr3:122440366(+) A-G intron -    22484847
chr3:122440411(+) T-G intron -    22484847
chr3:122441903(+) G-C intron -    22484847
chr3:122443330(+) G-T intron -    22484847
chr3:122443429(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PARP14
chr3:122399628-122399629(+) m6A 5'UTR       24981863
chr3:122399794-122399795(+) m6A CDS       24981863
chr3:122399800-122399801(+) m6A CDS       24981863
chr3:122411255-122411256(+) m6A CDS//intron       24981863
chr3:122411303-122411304(+) m6A CDS//intron       24981863//22575960
chr3:122418531-122418532(+) m6A CDS       24981863//27773535//22575960
chr3:122418544-122418545(+) m6A CDS       24981863//27773535//22575960
chr3:122418632-122418633(+) m6A CDS       24284625//24981863//26404942//27773535//22575960
chr3:122418863-122418864(+) m6A CDS       24981863
chr3:122418936-122418937(+) m6A CDS       24981863
chr3:122419004-122419005(+) m6A CDS       24981863
chr3:122419049-122419050(+) m6A CDS       24981863
chr3:122419272-122419273(+) m6A CDS       24209618//24981863//27773535
chr3:122419289-122419290(+) m6A CDS       24209618//24981863//27773535
chr3:122419321-122419322(+) m6A CDS       24209618//24981863//27773535
chr3:122419369-122419370(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960
chr3:122419398-122419399(+) m6A CDS//exon       24284625//24981863//26404942//27773535//22575960
chr3:122419403-122419404(+) m6A CDS//exon       24284625//24981863//26404942//27773535//22575960
chr3:122419419-122419420(+) m6A CDS//exon       24284625//24981863//26404942//27773535//22575960
chr3:122419462-122419463(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960
chr3:122419529-122419530(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960
chr3:122419564-122419565(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960
chr3:122419586-122419587(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960
chr3:122419722-122419723(+) m6A CDS//exon       24284625//24209618//24981863//22575960
chr3:122419786-122419787(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960
chr3:122419877-122419878(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960
chr3:122419974-122419975(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960
chr3:122420206-122420207(+) m6A CDS//exon       24284625//24209618//24981863
chr3:122420231-122420232(+) m6A CDS//exon       24284625//24209618//24981863
chr3:122420253-122420254(+) m6A CDS//exon       24284625//24209618//24981863//26404942
chr3:122420296-122420297(+) m6A CDS//exon       24284625//24209618//24981863//26404942//22575960
chr3:122420326-122420327(+) m6A CDS//exon       24284625//24981863//22575960
chr3:122420401-122420402(+) m6A CDS//exon       24284625//24981863//22575960
chr3:122422671-122422672(+) m6A CDS//exon       24981863
chr3:122422694-122422695(+) m6A CDS//exon       24981863
chr3:122422704-122422705(+) m6A CDS//exon       24981863
chr3:122422741-122422742(+) m6A CDS//exon       24981863
chr3:122422760-122422761(+) m6A CDS//exon       24981863
chr3:122437267-122437268(+) m6A CDS//exon       24209618//24981863//22575960
chr3:122437340-122437341(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960
chr3:122437356-122437357(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960
chr3:122437394-122437395(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960
chr3:122437463-122437464(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960
chr3:122437473-122437474(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960
chr3:122437566-122437567(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960
chr3:122437693-122437694(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960
chr3:122437733-122437734(+) m6A CDS//exon       24209618//24981863//27773535
chr3:122437739-122437740(+) m6A CDS//exon       24209618//24981863//27773535
chr3:122437757-122437758(+) m6A CDS//exon       24209618//24981863//27773535
chr3:122446712-122446713(+) m6A 3'UTR//CDS       24981863
chr3:122446736-122446737(+) m6A 3'UTR//CDS       24981863
chr3:122446766-122446767(+) m6A 3'UTR//CDS       24981863
chr3:122447174-122447175(+) m6A 3'UTR//CDS       24981863//22575960
chr3:122447224-122447225(+) m6A 3'UTR//CDS       24981863//22575960
chr3:122447322-122447323(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22575960
chr3:122447500-122447501(+) m6A 3'UTR       24981863
chr3:122447614-122447615(+) m6A 3'UTR       26404942
chr3:122447692-122447693(+) m6A 3'UTR       24981863//26404942
chr3:122447714-122447715(+) m6A 3'UTR       26404942
chr3:122447757-122447758(+) m6A 3'UTR       26404942
chr3:122449290-122449291(+) m6A 3'UTR       24981863
chr3:122449306-122449307(+) m6A 3'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3174
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
PARP14
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol K562 cells     -
Exosome Blood     -
Insoluble cytoplasm K562 cells     -
Nucleus Colon cancer cells     24393600
Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -
Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3174
Interactor2: PARP14

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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