Basic Information:

  VIRBase ID:  

HHID00072454

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3174:  MIMAT0015051          ADRB2:  NM_000024     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3174	ADRB2
miRBase Accession/Entrez ID	MIMAT0015051	154
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	ADRB2R//ADRBR//B2AR//BAR//BETA2AR

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3174	rs1159846130 chr15:90006777    A/G rs1295514792 chr15:90006764    T/TGTTAGAGATGC rs775051847 chr15:90006779    G/C

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ADRB2	chr5:148206691-148206692(+) m6A CDS       24284625//24981863//22608085 chr5:148206721-148206722(+) m6A CDS       24284625//24981863//22608085 chr5:148206760-148206761(+) m6A CDS       24284625//24981863//22608085 chr5:148206958-148206959(+) m6A CDS       24284625//22608085 chr5:148206980-148206981(+) m6A CDS       24284625//22608085 chr5:148207124-148207125(+) m6A CDS       24284625//25456834//24981863//22608085 chr5:148207164-148207165(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr5:148207500-148207501(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr5:148207518-148207519(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr5:148207532-148207533(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr5:148207550-148207551(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr5:148207658-148207659(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr5:148207676-148207677(+) m6A 3'UTR       24284625//24981863//22608085 chr5:148207683-148207684(+) m6A 3'UTR       24284625//24981863//22608085 chr5:148207710-148207711(+) m6A 3'UTR       24981863//22608085 chr5:148208019-148208020(+) m6A 3'UTR       24284625//24981863//22608085 chr5:148208043-148208044(+) m6A 3'UTR       24284625//24981863//22608085 chr5:148208058-148208059(+) m6A 3'UTR       24284625//24981863//22608085 chr5:148208064-148208065(+) m6A 3'UTR       24284625//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3174	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	ADRB2	Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3174
Interactor2: ADRB2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.