Basic Information:

  VIRBase ID:  

HHID00072306

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3150a-3p:  MIMAT0015023          ZFP36:  NM_003407     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3150a-3p	ZFP36
miRBase Accession/Entrez ID	MIMAT0015023	7538
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	G0S24//GOS24//NUP475//RNF162A//TIS11//TTP//zfp-36

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3150a-3p	rs1005806635 chr8:95072962    C/CT rs372692847 chr8:95072962    C/T

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ZFP36	chr19:39897641-39897642(+) m6A CDS//intron       24981863 chr19:39897729-39897730(+) m6A CDS//intron       24981863 chr19:39898093-39898094(+) m6A CDS//intron       25456834//24981863 chr19:39898100-39898101(+) m6A CDS//intron       25456834//24981863 chr19:39898115-39898116(+) m6A CDS//intron       25456834 chr19:39898433-39898434(+) m6A 3'UTR//CDS       25456834 chr19:39898465-39898466(+) m6A 3'UTR//CDS       24284625 chr19:39898673-39898674(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942 chr19:39898688-39898689(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942 chr19:39898792-39898793(+) m6A 3'UTR//CDS       24284625//25456834//24981863//26404942 chr19:39898869-39898870(+) m6A CDS       24284625//24209618//25456834//24981863//26404942 chr19:39898943-39898944(+) m6A CDS       24284625//24209618//25456834//24981863 chr19:39899028-39899029(+) m6A CDS       24284625//25456834//24981863 chr19:39899088-39899089(+) m6A CDS       24284625//25456834//24981863 chr19:39899168-39899169(+) m6A CDS       24284625//24981863 chr19:39899413-39899414(+) m6A 3'UTR       25456834//24981863//26404942 chr19:39899430-39899431(+) m6A 3'UTR       25456834//24981863//26404942 chr19:39899439-39899440(+) m6A 3'UTR       25456834//24981863//26404942 chr19:39899703-39899704(+) m6A 3'UTR       27773535 chr19:39899735-39899736(+) m6A 3'UTR       27773535 chr19:39899804-39899805(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3150a-3p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	ZFP36	Exosome Blood     - Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3150a-3p
Interactor2: ZFP36

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.