Basic Information:

  VIRBase ID:  

HHID00072294

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3150a-3p:  MIMAT0015023          GNB2:  NM_005273     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3150a-3p	GNB2
miRBase Accession/Entrez ID	MIMAT0015023	2783
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3150a-3p	rs1005806635 chr8:95072962    C/CT rs372692847 chr8:95072962    C/T

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	GNB2	chr7:100271197-100271198(+) m6A 5'UTR       24981863 chr7:100271239-100271240(+) m6A 5'UTR//intron       24981863 chr7:100271491-100271492(+) m6A 5'UTR//intron       24209618//25456834//24981863//27773536 chr7:100273911-100273912(+) m6A CDS//exon//intron       24284625//24209618 chr7:100273934-100273935(+) m6A CDS//exon//intron       24284625//24209618 chr7:100274179-100274180(+) m6A 5'UTR//CDS//exon//intron       24284625//24209618 chr7:100274331-100274332(+) m6A 5'UTR//CDS//exon//intron       24284625//24209618 chr7:100274357-100274358(+) m6A CDS//exon//intron       24284625 chr7:100274366-100274367(+) m6A CDS//exon//intron       24284625 chr7:100274411-100274412(+) m6A CDS//exon//intron       24284625 chr7:100274889-100274890(+) m6A exon//intron       - chr7:100275018-100275019(+) m6A 5'UTR//CDS//exon//intron       24284625 chr7:100275181-100275182(+) m6A CDS//exon       24284625//22575960 chr7:100275205-100275206(+) m6A CDS//exon       24284625//22575960 chr7:100275234-100275235(+) m6A CDS//exon       24284625//22575960 chr7:100275348-100275349(+) m6A exon//intron       24284625//22575960 chr7:100275731-100275732(+) m6A CDS//exon       22575960 chr7:100275739-100275740(+) m6A CDS//exon       22575960 chr7:100275751-100275752(+) m6A CDS//exon       22575960 chr7:100275768-100275769(+) m6A CDS//exon       22575960 chr7:100275883-100275884(+) m6A CDS//exon       22575960 chr7:100276398-100276399(+) m6A CDS//exon       22575960 chr7:100276409-100276410(+) Am CDS//exon       - chr7:100276419-100276420(+) m6A CDS//exon       22575960 chr7:100276701-100276702(+) m6A 3'UTR//exon       - chr7:100276725-100276726(+) m6A 3'UTR//exon       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3150a-3p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	GNB2	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3150a-3p
Interactor2: GNB2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.